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  • Open Access

    ARTICLE

    Promotion of Growth of True Pulmonary Arteries as a First Step in Staged Repair of Pulmonary Atresia, Ventricular Septal Defect and Major Aorto-Pulmonary Collateral Arteries

    Pieter C. van de Woestijne1,*, Ingrid M. van Beynum2, Kevin M. Veen3, Ad J. J. C Bogers1

    Congenital Heart Disease, Vol.19, No.6, pp. 593-601, 2024, DOI:10.32604/chd.2025.060607 - 27 January 2025

    Abstract Background: Construction of a central shunt by connection of hypoplastic true pulmonary arteries to the ascending aorta (AO) can be performed as a first step in staged repair of pulmonary atresia with ventricular septal defect and major aorto-pulmonary collateral arteries (PA-VSD-MAPCAs) intended to promote growth and development of the central pulmonary arteries. Methods: To determine early and intermediate-term growth of true pulmonary arteries after their connection to the AO as a first step in staged repair of PA-VSD-MAPCAs, we reviewed all angiographic studies and CT imaging of patients, treated in our tertiary referral center in… More >

  • Open Access

    REVIEW

    Tetralogy of Fallot: Anatomy, Physiology, and Outcomes

    Edo Bedzra1,*, Eli Contorno2, Herra Javed2, Amna Qasim3, James St. Louis4, Taufiek Konrad Rajab2

    Congenital Heart Disease, Vol.19, No.6, pp. 541-562, 2024, DOI:10.32604/chd.2025.059788 - 27 January 2025

    Abstract Since the first identification of Tetralogy of Fallot in 1671, consisting of a combination of anatomical defects including biventricular origin of the aorta, maligned ventricular septal defect, overriding aorta, and narrowing or atresia of the pulmonary outflow tract. The first successful operation consisted of a shunt between the left subclavian artery and pulmonary artery. Following this palliative procedure, complete repair is performed once the patient reaches indicative criteria. Since the first attempts at surgical palliation and repair, techniques and outcomes have improved drastically. Definitive repair of Tetralogy of Fallot consists of a multi-patch closure of More >

  • Open Access

    CASE REPORT

    Case Report: Laubry-Pezzi Syndrome: Confronting the Lethal Nexus of Life-Threatening Complications in Resource Constrained Settings

    Hayatu Uma1,*, Abdulaziz Aminu1, Raghu Cherukupalli2, Femi Akindotun Akintomide1, Abdul Habu3, Aisha Aminu Lawal1, Adamu Mohammad1

    Congenital Heart Disease, Vol.19, No.6, pp. 635-645, 2024, DOI:10.32604/chd.2025.056641 - 27 January 2025

    Abstract Laubry-Pezzi syndrome (L-PS) is a rare congenital heart disease characterized by a ventricular septal defect (VSD) and aortic valve prolapse. These cardiac lesions predispose individuals to infective endocarditis (IE), a life-threatening complication, especially in resource-constrained settings. A 17-year-old male presented with a three-week history of fever and headache, and a one-week history of abdominal pain, vomiting, and diarrhea. On presentation, he appeared toxic, was febrile, tachypneic, tachycardic, and blood pressure of 120/30 mmHg, and heart sounds were S1, S2. Abdominal examination revealed generalized tenderness. A provisional diagnosis of typhoid sepsis with intestinal perforation was considered.… More >

  • Open Access

    ARTICLE

    Long-Term Follow-Up Study on Electrophysiology Guidance for Transcatheter Closure of Perimembranous Ventricular Septal Defect in Adults

    Wenrui Li1, Nanshan Xie1, Xianzhang Zhan1, Ziyang Yang2, Hezhi Li1, Caojin Zhang1,*

    Congenital Heart Disease, Vol.19, No.5, pp. 445-455, 2024, DOI:10.32604/chd.2024.053604 - 31 December 2024

    Abstract Objectives: To explore the feasibility and efficacy of electrophysiology guidance for transcatheter closure of perimembranous ventricular septal defect (PmVSD) in adults. Methods: Adult patients with PmVSD who underwent transcatheter in Guangdong Provincial People’s Hospital, Guangdong Cardiovascular Institute from February 2016 to January 2018 were selected. The distribution of the His-Purkinje system (HPS) close to the margins of PmVSD in the left ventricle was identified using three-dimensional (3D) electro-anatomic mapping and near-field HPS was further confirmed by different pacing protocols. The follow-up protocol included electrocardiogram (ECG)and transthoracic echocardiography at 6, 24, 72 h, 1, 3, 6… More >

  • Open Access

    REVIEW

    Right Axillary Thoracotomy Should Be the Standard of Care for Repair of Non-Complex Congenital Heart Defects in Infants and Children

    Sameh M. Said1,2,*, Yasin Essa1

    Congenital Heart Disease, Vol.19, No.4, pp. 407-417, 2024, DOI:10.32604/chd.2024.055636 - 31 October 2024

    Abstract Minimally invasive approaches for cardiac surgery in children have been lagging in comparison to the adult world. A wide range of the most common congenital heart defects in infants and children can be repaired successfully through a variety of non-sternotomy incisions. This has been shown to be associated with superior cosmetic results, shorter hospital stays, and rapid return to full activity compared to sternotomy. These approaches have been around for decades, but they have not been widely adopted for a variety of reasons. Right axillary thoracotomy is one of these approaches that we believe should More >

  • Open Access

    ARTICLE

    Surgical Repair of Ventricular Septal Defect in Neonates: Indications and Outcomes

    Jae Hong Lee1, Sungkyu Cho2,*, Jae Gun Kwak2, Hye Won Kwon2, Woong-Han Kim2, Mi Kyoung Song3, Sang-Yun Lee3, Gi Beom Kim3, Eun Jung Bae3

    Congenital Heart Disease, Vol.19, No.1, pp. 69-83, 2024, DOI:10.32604/chd.2024.045137 - 20 March 2024

    Abstract Background: The optimal surgical timing and clinical outcomes of ventricular septal defect (VSD) closure in neonates remain unclear. We aimed to evaluate the clinical outcomes of VSD closure in neonates (age ≤ 30 days). Methods: We retrospectively reviewed 50 consecutive neonates who underwent VSD closure for isolated VSDs between August 2003 and June 2021. Indications for the procedure included congestive heart failure/failure to thrive and pulmonary hypertension. Major adverse events (MAEs) were defined as the composite of all-cause mortality, reoperation, persistent atrioventricular block, and significant (≥grade 2) valvular dysfunction. Results: The median age and body weight… More >

  • Open Access

    ARTICLE

    Mortality Rates of Ventricular Septal Defect for Children in Kazakhstan: Spatio-Temporal Epidemiological Appraisal

    Akkerbez Adilbekova1,3,*, Shukhrat Marassulov1, Bakhytzhan Nurkeev1, Saken Kozhakhmetov2, Aikorkem Badambekova3

    Congenital Heart Disease, Vol.18, No.4, pp. 447-459, 2023, DOI:10.32604/chd.2023.028742 - 15 September 2023

    Abstract Objective: The aim is to study the trends in ventricular septal defect (VSD) mortality in children in Kazakhstan. Methods: The retrospective study was done for the period 2011–2020. Descriptive and analytical methods of epidemiology were applied. The universally acknowledged methodology used in sanitary statistics is used to calculate the extensive, crude, and age-specific mortality rates. Results: Kazakhstan is thought to be seeing an increase in mortality from VSDs in children. As a result, this study for the years 2011 to 2020 was conducted to retrospectively assess data from the central registration of the Bureau of National… More > Graphic Abstract

    Mortality Rates of Ventricular Septal Defect for Children in Kazakhstan: Spatio-Temporal Epidemiological Appraisal

  • Open Access

    ARTICLE

    Quantitative Parameters Analysis for Prenatally Echocardiographic Diagnosis of Atrioventricular Septal Defects

    Xiaoxue Zhou1, Tingyang Yang2, Ye Zhang1, Yanping Ruan1, Jiancheng Han1, Xiaowei Liu1, Ying Zhao1, Xiaoyan Gu1, Tingting Liu1, Hairui Wang1, Yihua He1,*

    Congenital Heart Disease, Vol.18, No.3, pp. 387-397, 2023, DOI:10.32604/chd.2023.029060 - 09 June 2023

    Abstract Background: Atrioventricular septal defects (AVSDs) are screened and diagnosed usually rely on the imaging characteristics of fetal echocardiography (FE). However, diagnosis on images is heavily depended on sonographers’ experience and the quantitative data are rarely studied. Objective: This study aimed to realize the prenatal diagnosis of AVSDs by analyzing the quantitative data on FE. Methods: One hundred and thirteen cardiac quantitative data was analyzed in 370 normal and 49 AVSDs fetuses retrospectively. The top six with the highest diagnostic accuracy rate were acquired according to the area under the curve (AUC), and the diagnostic value of… More >

  • Open Access

    ARTICLE

    Transcatheter Ventricular Septal Defect Closure with Nit-Occlud Lê VSD Device—Five Years’ Experience and Literature Review

    Ivana B. Cerović1, Vladislav A. Vukomanović1,2, Jovan Lj. Košutić1,2, Mila S. Stajević1,2, Sanja S. Ninić1, Saša S. Popović1, Ivan D. Dizdarević1, Staša D. Krasić1, Sergej M. Prijić1,2,*

    Congenital Heart Disease, Vol.18, No.3, pp. 361-371, 2023, DOI:10.32604/chd.2023.026533 - 09 June 2023

    Abstract Introduction: Transcatheter closure is an alternative to ventricular septal defect (VSD) occlusion surgery. Nit-Occlud Lê VSD coil is a new device yet to be evaluated. The study aimed to evaluate immediate and midterm results after transcatheter closure with the Nit-Occlud Lê VSD device. Methods: The retrospective analysis included 30 patients with VSD referred for closure during the period from October 2015 to December 2020. Results: At the time of intervention, the patients’ mean age and body weights were 7.5 ± 5.6 years and 29.3 ± 19.1 kg. The majority of the defects had perimembranous location (24/30), four defects had muscular and… More >

  • Open Access

    ARTICLE

    Effects of General Anesthesia on the Results of Cardiac Catheterization in Pediatric Patients with Ventricular Septal Defect

    Kiyotaka Go1,2, Taichi Kato2,*, Machiko Kito1, Yoshihito Morimoto1,2, Satoru Kawai1, Hidenori Yamamoto2, Yoshie Fukasawa2, Kazushi Yasuda1

    Congenital Heart Disease, Vol.18, No.2, pp. 235-243, 2023, DOI:10.32604/chd.2023.027590 - 15 March 2023

    Abstract Background: There is no gold standard sedation method for pediatric cardiac catheterization. In congenital heart diseases with intracardiac shunts, hemodynamic parameters are prone to change depending on the ventilation conditions and anesthetics, although few studies have examined these effects. The purpose of this study was to investigate the effects of two different sedation methods on the hemodynamic parameters. Methods: This study retrospectively evaluated consecutive patients with ventricular septal defect (VSD) below 1 year of age who underwent cardiac catheterization at Aichi Children’s Health and Medical Center, who were divided into age- and VSD diameter-matched general anesthesia… More >

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