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  • Open Access

    ARTICLE

    Puerarin inactivates NLRP3-mediated pyroptotic cell death to alleviate cerebral ischemia/reperfusion (I/R) injury through modulating the LncRNA DUXAP8/miR-223-3p axis

    ZHENGUO SHI#,*, QIAOYUN WU#, HAIYAN SHI, SONGTIE YING, LIANG TAO

    BIOCELL, Vol.46, No.4, pp. 979-988, 2022, DOI:10.32604/biocell.2022.015345

    Abstract NLRP3 inflammasome-mediated cell pyroptosis aggravates the development of cerebral ischemia/reperfusion (I/R) injury, and the aim of this study is to investigate the potential utilization of the Chinese medicine, Puerarin, in treating this disease. Through conducting in vitro and in vivo experiments, the present study illustrated that Puerarin regulated LncRNA double homeobox A pseudogene 8 (DUXAP8)/miR-223-3p axis to inactivate NLRP3-mediated pyroptotic cell death, resulting in the attenuation of I/R injury. Specifically, the cerebral I/R injury in rat models and hypoxia/reoxygenation (H/R) in primary hippocampus neuron (PHN) cells were inducted, which were subsequently exposed to Puerarin treatment. As expected, we validated that… More >

  • Open Access

    ARTICLE

    The role of baicalin on carbon tetrachloride induced liver fibrosis

    MENGTING LI*, YI-ER QIU, KAIFENG ZHENG

    BIOCELL, Vol.46, No.4, pp. 1089-1096, 2022, DOI:10.32604/biocell.2022.013432

    Abstract The effect of the baicalin, a bio-active flavonoid extracted from Scutellaria baicalensis Georgi, on the carbon tetrachloride (CCl4) induced liver fibrosis was investigated. To compare the effect of baicalin on the liver fibrosis, five different groups of rats treated by 100, 200, and 400 mg/kg baicalin were studied. Upon CCl4 treatment, the levels of procollagen type III, aspartate aminotransferase, aminotransferase, hyaluronic acid, and hydroxyproline were significantly increased, whereas the superoxide dismutase and glutathione peroxidase content were decreased. These changes in the biochemical parameters, which are associated with liver function, were significantly attenuated by the baicalin treatment, suggesting that baicalin can… More >

  • Open Access

    ARTICLE

    New 5G Kaiser-Based Windowing to Reduce Out of Band Emission

    Ahmed Hammoodi1, Lukman Audah1 , Laith Al-Jobouri2,*, Mazin Abed Mohammed3, Mustafa S. Aljumaily4

    CMC-Computers, Materials & Continua, Vol.71, No.2, pp. 2721-2738, 2022, DOI:10.32604/cmc.2022.020091

    Abstract OFDM based waveforms are considered as the main part of the latest cellular communications standard (namely 5G). Many inherited problems from the OFDM-Based LTE are still under investigation. Getting rid of the out of band emissions is one of these problems. Ensuring low out of band emission (OOBE) is deemed as one of the most critical challenges to support development of future technologies such as 6G and beyond. Universal Filtered Multi Carrier (UFMC) has been considered as one of the candidate waveforms for the 5G communications due to its robustness against Inter Carrier Interference (ICI) and the Inter Symbol Interference… More >

  • Open Access

    ARTICLE

    Sine Trigonometry Operational Laws for Complex Neutrosophic Sets and Their Aggregation Operators in Material Selection

    D. Ajay1, J. Aldring1, G. Rajchakit2, P. Hammachukiattikul3, N. Boonsatit4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.2, pp. 1033-1076, 2022, DOI:10.32604/cmes.2022.018267

    Abstract In this paper, sine trigonometry operational laws (ST-OLs) have been extended to neutrosophic sets (NSs) and the operations and functionality of these laws are studied. Then, extending these ST-OLs to complex neutrosophic sets (CNSs) forms the core of this work. Some of the mathematical properties are proved based on ST-OLs. Fundamental operations and the distance measures between complex neutrosophic numbers (CNNs) based on the ST-OLs are discussed with numerical illustrations. Further the arithmetic and geometric aggregation operators are established and their properties are verified with numerical data. The general properties of the developed sine trigonometry weighted averaging/geometric aggregation operators for… More >

  • Open Access

    ARTICLE

    Range-Only UWB SLAM for Indoor Robot Localization Employing Multi-Interval EFIR Rauch-Tung-Striebel Smoother

    Yanli Gao1, Wanfeng Ma2, Jing Cao2, Jianling Qu1 and Yuan Xu2,3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.2, pp. 1221-1237, 2022, DOI:10.32604/cmes.2022.017533

    Abstract For improving the localization accuracy, a multi-interval extended finite impulse response (EFIR)-based RauchTung-Striebel (R-T-S) smoother is proposed for the range-only ultra wide band (UWB) simultaneous localization and mapping (SLAM) for robot localization. In this mode, the EFIR R-T-S (ERTS) smoother employs EFIR filter as the forward filter and the R-T-S smoothing method to smooth the EFIR filter’s output. When the east or the north position is considered as stance, the ERTS is used to smooth the position directly. Moreover, the estimation of the UWB Reference Nodes’ (RNs’) position is smoothed by the R-T-S smooth method in parallel. The test illustrates… More >

  • Open Access

    ARTICLE

    Time Synchronized Velocity Error for Trajectory Compression

    Haibao Jiang1, Dezhi Han1,*, Han Liu1, Jiuzhang Han1 and Wenjing Nie2

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.2, pp. 1193-1219, 2022, DOI:10.32604/cmes.2022.017663

    Abstract Nowadays, distance is usually used to evaluate the error of trajectory compression. These methods can effectively indicate the level of geometric similarity between the compressed and the raw trajectory, but it ignores the velocity error in the compression. To fill the gap of these methods, assuming the velocity changes linearly, a mathematical model called SVE (Time Synchronized Velocity Error) for evaluating compression error is designed, which can evaluate the velocity error effectively, conveniently and accurately. Based on this model, an innovative algorithm called SW-MSVE (Minimum Time Synchronized Velocity Error Based on Sliding Window) is proposed, which can minimize the velocity… More >

  • Open Access

    ARTICLE

    Lacunary Generating Functions of Hybrid Type Polynomials in Viewpoint of Symbolic Approach

    Nusrat Raza1, Umme Zainab2 and Serkan Araci3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.2, pp. 903-921, 2022, DOI:10.32604/cmes.2022.017669

    Abstract In this paper, we introduce mon-symbolic method to obtain the generating functions of the hybrid class of Hermite-associated Laguerre and its associated polynomials. We obtain the series definitions of these hybrid special polynomials. Also, we derive the double lacunary generating functions of the Hermite-Laguerre polynomials and the Hermite-Laguerre-Wright polynomials. Further, we find multiplicative and derivative operators for the Hermite-Laguerre-Wright polynomials which helps to find the symbolic differential equation of the Hermite-Laguerre-Wright polynomials. Some concluding remarks are also given. More >

  • Open Access

    REVIEW

    Human Stress Recognition from Facial Thermal-Based Signature: A Literature Survey

    Darshan Babu L. Arasu1, Ahmad Sufril Azlan Mohamed1,*, Nur Intan Raihana Ruhaiyem1, Nagaletchimee Annamalai2, Syaheerah Lebai Lutfi1, Mustafa M. Al Qudah1

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.2, pp. 633-652, 2022, DOI:10.32604/cmes.2021.016985

    Abstract Stress is a normal reaction of the human organism which triggered in situations that require a certain level of activation. This reaction has both positive and negative effects on everyone’s life. Therefore, stress management is of vital importance in maintaining the psychological balance of a person. Thermal-based imaging technique is becoming popular among researchers due to its non-contact conductive nature. Moreover, thermal-based imaging has shown promising results in detecting stress in a non-contact and non-invasive manner. Compared to other non-contact stress detection methods such as pupil dilation, keystroke behavior, social media interaction and voice modulation, thermal-based imaging provides better features… More >

  • Open Access

    ARTICLE

    CFD-Based Evaluation of Flow and Temperature Characteristics of Airflow in an Aircraft Cockpit

    Xiaosai Duan, Suihuai Yu*, Jianjie Chu, Dengkai Chen and Zhaojing Su

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.2, pp. 701-721, 2022, DOI:10.32604/cmes.2022.016779

    Abstract The rational design of airflow distribution is of great importance for comfort and energy conservation. Several numerical investigations of flow and temperature characteristics in cockpits have been performed to study the distinct airflow distribution. This study developed the coupled heat transfer model of radiation, convection, and heat conduction for the cockpit flight environment. A three-dimensional physical model was created and a shear stress transfer (SST) k-w turbulence model was well verified with a high prediction accuracy of 91% for the experimental data. The strong inhomogeneous flow and temperature distribution were captured for various initial operating conditions (inlet temperature, inlet pressure,… More >

  • Open Access

    ARTICLE

    Theoretical Investigation of Two-Dimensional Nonlinear Radiative Thermionics in Nano-MHD for Solar Insolation: A Semi-Empirical Approach

    Usman Inayat1,*, Shaukat Iqbal1, Tareq Manzoor2

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.2, pp. 751-776, 2022, DOI:10.32604/cmes.2022.018665

    Abstract In this contemporary study, theoritical investigation of nanofluidic model is thought-out. Two-dimensional nanomaterials based mixed flow is considered here. Convective solar radiative heat transport properties have been investigated over a nonlinearly stretched wall in the presence of magneto-hydrodynamic (MHD), by innovative application of semi analytical “optimal homotopy asymptotic method (OHAM)”. OHAM does not require any discretization, linearization and small parameter assumption. OHAM describes extremely precise order solutions without the need of computing further higher order terms, therefore, fast convergence is observed. Nanofluidic governing model is transformed into system of ordinary differential equations (ODEs) by exploitation of similarity transformation. To study… More >

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