Tao Xu^1,*, Fangqiang Zuo¹, Kai Zheng^2,*

International Journal of Mental Health Promotion, Vol., , DOI:10.32604/ijmhp.2023.043226

Abstract Background: This study aimed to investigate the relationship between parental educational expectations and adolescent mental health problems, with academic pressure as a moderating variable. Methods: This study was based on the baseline data of the China Education Panel Survey, which was collected within one school year during 2013–2014. It included 19,958 samples from seventh and ninth graders, who ranged from 11 to 18 years old. After removing missing values and conducting relevant data processing, the effective sample size for analysis was 16344. The OLS (Ordinary Least Squares) multiple linear regression analysis was used to examine the relationship between parental educational… More >

Zhongping Chen, Weigong Zhang^*

Structural Durability & Health Monitoring, Vol., , DOI:10.32604/sdhm.2023.043563

Abstract Automatic control technology is the basis of road robot improvement, according to the characteristics of construction equipment and functions, the research will be input type perception from positioning acquisition, real-world monitoring, the process will use RTK-GNSS positional perception technology, by projecting the left side of the earth from Gauss-Krueger projection method, and then carry out the Cartesian conversion based on the characteristics of drawing; steering control system is the core of the electric drive unmanned module, on the basis of the analysis of the composition of the steering system of unmanned engineering vehicles, the steering system key components such as… More >

Fanny Delehaye^1,2,*, Olivier Dejardin^1,3, Isabelle Pellier⁴, Ludivine Launay^1,5, Maxime Esvan⁶, Damien Bodet², Liana Carausu⁷, Julien Lejeune⁸, Frédéric Millot⁹, Caroline Thomas¹⁰, Virginie Gandemer¹¹, Arnaud Alves^1,12, Julien Rod^1,13

Psycho-Oncologie, Vol., , DOI:10.32604/po.2024.043073

Abstract The posttreatment period is a key part of the management of pediatric cancer. During this time, school and psychological difficulties have been described in childhood cancer survivors (CCS) and can be prognostic for the success of social reintegration. This study estimated the influence of the household’s socioeconomic status (SES) on these psychosocial difficulties. This study is based on a prospective multicentric database and focused on children who received a psychosocial evaluation during their follow-up from 2013 to 2020. We retrieved data on school and psychological difficulties. Household SES was estimated by a social deprivation score. Data from1003 patients were analyzed.… More >

Rossi Silvia^1,2,*, Sandrine de Montgolfier^1,3, Joëlle Kivits⁴

Psycho-Oncologie, Vol., , DOI:10.32604/po.2024.042709

Abstract Aims: Health democracy requires tools and methodologies to involve non-scientific actors in the development and implementation of health policies. Storytelling could be one of the tools to make health democracy effective. Our aim is to describe how storytelling is used in relation to health democracy, the aims of its use, the methodology adopted and the results obtained. Procedure: We conducted a narrative review of the literature. Our search equation was composed by the keyword “narration” and its variations “récit de vie”, “histoire de vie” and “medécine narrative” and by the keyword “démocratie en santé” / “démocratie sanitaire”. Results: We obtained… More >

Lei Zhu^1,#, Lihe Hou^1,3,#, Yu Zhang¹, Yang Jiang¹, Yi Wang^1,2, Meiping Zhang^1,2, Mingzhu Zhao^1,2,*, Kangyu Wang^1,2,*

Phyton-International Journal of Experimental Botany, Vol., , DOI:10.32604/phyton.2024.047938

Abstract Panax ginseng C. A. Mey. is an important plant species used in traditional Chinese medicine, whose primary active ingredient is a ginsenoside. Ginsenoside biosynthesis is not only regulated by transcription factors but also controlled by a variety of structural genes. Nonetheless, the molecular mechanism underlying ginsenoside biosynthesis has always been a topic in the discussion of ginseng secondary metabolites. Squalene epoxidase (SQE) is a key enzyme in the mevalonic acid pathway, which affects the biosynthesis of secondary metabolites such as terpenoid. Using ginseng transcriptome, expression, and ginsenoside content databases, this study employed bioinformatic methods to systematically analyze the genes encoding… More >

Eduardo Burgos-Valencia^1,#, Federico García-Laynes^1,#, Ileana Echevarría-Machado¹, Fatima Medina-Lara¹, Miriam Monforte-González¹, José Narváez-Zapata^2,*, Manuel Martínez-Estévez^1,*

Phyton-International Journal of Experimental Botany, Vol., , DOI:10.32604/phyton.2023.046943

Abstract Habanero pepper (Capsicum chinense Jacq.) is a crop of economic relevance in the Peninsula of Yucatan. Its fruits have a high level of capsaicinoids compared to peppers grown in other regions of the world, which gives them industrial importance. Soil is an important factor that affects pepper development, nutritional quality, and capsaicinoid content. However, the effect of soil type on fruit development and capsaicinoid metabolism has been little understood. This work aimed to compare the effect of soils with contrasting characteristics, black soil (BS) and red soil (RS), on the expression of genes related to the development of fruits, and… More >

Jingtao Hu¹, Wenjing Chen¹, Yanyan Duan¹, Yingjing Ru¹, Wenqing Cao¹, Pingwei Xiang², Chengzhi Huang², Li Zhang², Jingsheng Chen¹, Liping Gan^1,*

Phyton-International Journal of Experimental Botany, Vol., , DOI:10.32604/phyton.2024.046521

Abstract Abiotic stress, including flooding, seriously affects the normal growth and development of plants. Mulberry (Morus alba), a species known for its flood resistance, is cultivated worldwide for economic purposes. The transcriptomic analysis has identified numerous differentially expressed genes (DEGs) involved in submergence tolerance in mulberry plants. However, a comprehensive analyses of metabolite types and changes under flooding stress in mulberry remain unreported. A non-targeted metabolomic analysis utilizing liquid chromatography-tandem mass spectrometry (LC-MS/MS) was conducted to further investigate the effects of flooding stress on mulberry. A total of 1,169 metabolites were identified, with 331 differentially accumulated metabolites (DAMs) exhibiting up-regulation in… More >

MENNA AL-ADL^1,*, MAGDY M. YOUSSEF¹, AHMED EL-SEBAIE², SHERIF REFAAT³, AFAF EL-SAID⁴

Oncology Research, Vol., , DOI:10.32604/or.2024.047021

Abstract Cytochromes P450 (CYPs) play a prominent role in catalyzing phase I xenobiotic biotransformation and account for about 75% of the total metabolism of commercially available drugs, including chemotherapeutics. The gene expression and enzyme activity of CYPs are variable between individuals, which subsequently leads to different patterns of susceptibility to carcinogenesis by genotoxic xenobiotics, as well as differences in the efficacy and toxicity of clinically used drugs. This research aimed to examine the presence of the CYP2B6*9 polymorphism and its possible association with the incidence of B-CLL in Egyptian patients, as well as the clinical outcome after receiving cyclophosphamide chemotherapy. DNA… More > Graphic Abstract

YUE ZHANG^1,#, WENYU YANG^1,#, XIAOWANG HAN^1,#, YUE QIAO¹, HAITAO WANG², TING CHEN¹, TIANYING LI¹, WEN-BIN OU^1,*

Oncology Research, Vol., , DOI:10.32604/or.2024.045025

Abstract It has been shown that the high expression of human epididymis protein 4 (HE4) in most lung cancers is related to the poor prognosis of patients, but the mechanism of pathological transformation of HE4 in lung cancer is still unclear. The current study is expected to clarify the function and mechanism of HE4 in the occurrence and metastasis of lung adenocarcinoma (LUAD). Immunoblotting evaluated HE4 expression in lung cancer cell lines and biopsies, and through analysis of The Cancer Genome Atlas (TCGA) dataset. Frequent HE4 overexpression was demonstrated in LUAD, but not in lung squamous cell carcinoma (LUSC), indicating that… More >

XIAOXI WANG¹, YANFEI JIA², QIANG LI², QIANG YANG², YINGFENG LIU¹, BEIFENG WEI¹, XIANG NIU¹, YINJIE ZHANG¹, XIAODONG LUO², ZIYU ZHAO^1,*, PENG WANG^1,*

Oncology Research, Vol., , DOI:10.32604/or.2023.042581

Abstract MicroRNA (miR)-200b-3p has been associated with many tumors, but its involvement in pituitary adenoma is unclear. This study investigated the molecular mechanism underlying miR-200b-3p regulation in pituitary adenomas to provide a theoretical basis for treatment. Bioinformatics was used to analyze pituitary adenoma-related genes and screen new targets related to RECK and miRNA. As well, the relationship between miR-200b-3p and RECK protein was verified using a double-luciferase reporter gene assay. The expression of miR-200b-3p in clinical samples was analyzed by in situ hybridization. Transfection of the miR-200b-3p inhibitor and small interfering-RECK (si-RECK) was verified by qPCR. GH3 cell viability and proliferation… More >