Daniel Cardoso, Armando Rosales, David D. Thiel, Horacio Asbun, John A. Stauffer

Canadian Journal of Urology, Vol.29, No.1, pp. 11020-11023, 2022

Abstract Introduction: Renal cell carcinoma (RCC) is the most common primary neoplasia that metastasizes to the pancreas. Pancreatic metastasis (PM) occur in asymptomatic older patients and are identified during follow up. If resectable, surgery is the treatment of choice for long term survival. Our goal is to analyze outcomes of patients with RCC-PM.
Material and methods: We reviewed all patients with metastatic RCC (mRCC) who underwent resection, from known primary RCC and RCC-PM.
Results: There were 16 patients (mean age of 67 ± 8 years, male 8 (50%), mean BMI 29 ± 5.36 kg/m2). Half of them were asymptomatic.… More >

Tyler Overholt^1,2, Robert J. Evans¹, Gopal Badlani¹, Catherine A. Matthews¹, Stephen J. Walker^1,2

Canadian Journal of Urology, Vol.29, No.1, pp. 11012-11019, 2022

Abstract Introduction: To further facilitate understanding of disease pathophysiology and patient stratification in interstitial cystitis/bladder pain syndrome (IC/BPS), we utilized molecular phenotyping to compare three clinically distinct IC/BPS patient subgroups.
Materials and methods: Total RNA (miRNA and mRNA) was isolated via standard protocols from IC/BPS patient bladder biopsies and assayed on whole genome and microRNA expression arrays. Data from three patient subgroups (n = 4 per group): (1) low bladder capacity (BC; ≤ 400 cc) without Hunner’s lesion, (2) low BC with Hunner’s lesion, and (3) non-low BC (> 400 cc) were used in comparative analyses to evaluate… More >

Michael Uy¹, Richard Di Lena¹, Jen Hoogenes^1,2, Badr Al-Harbi³, Aidan Woodward⁴, Bobby Shayegan^1,2, Edward D. Matsumoto^1,2

Canadian Journal of Urology, Vol.29, No.1, pp. 11005-11011, 2022

Abstract Introduction: The relationship between obesity and nephrolithiasis is a well-documented phenomenon. Visceral adipose tissue (VAT) has been proposed to be an accurate indicator of metabolic derangement. We present a study that investigates the relationship between computed tomography (CT) delineated VAT measurements and 24-hour urine (24 HU) profiles in the context of profound weight loss.
Materials and methods: A total of 86 patients with a history of nephrolithiasis who underwent bariatric surgery were reviewed. All patients had pre and postoperative 24 HU analysis and CT kidney and urinary bladder performed. CT-based fat delineation program, AnalyzePro, was used to… More >

Judd W. Moul

Canadian Journal of Urology, Vol.29, No.1, pp. 11003-11004, 2022

Abstract This article has no abstract. More >

Sijun Liu^1,2, Zongwei Wang¹, Xingbo Long³, Aaron Fleishman¹, Xiangchun Huang⁴, Qingguang Wu², Boris Gershman¹, Aria F. Olumi¹

Canadian Journal of Urology, Vol.29, No.1, pp. 10992-11002, 2022

Abstract Introduction: To determine whether marital status combined with race serve as prognostic factors for survival in localized prostate cancer.
Materials and methods: Patients with localized prostate cancer were retrospectively extracted from the Surveillance, Epidemiology, and End Results (SEER) database. Chi-square test was used to investigate the association between marital status combined with race and other variables. Gray’s test was used to compare the cumulative incidence function of different variables. Multivariable analysis was conducted to assess prognostic factors after adjusting for other variables.
Results: A total of 207,219 patients with localized prostate cancer from the SEER database from 2010… More >

Cédric Charrois-Durand¹, Daniel Taussky¹, Guila Delouya¹, Daniel Liberman²

Canadian Journal of Urology, Vol.29, No.1, pp. 10986-10991, 2022

Abstract Introduction: To analyze biochemical failure-free survival and erectile dysfunction (ED) in younger men treated with prostate seed brachytherapy (PB).
Materials and methods: Included were patients ≤ 55 years treated with PB. Erectile function at baseline and after treatment were assessed using the physician-reported CTCAE version 4.0. Biochemical failure (BF) was defined according to the Phoenix Consensus definition (PSA nadir + 2 ng/mL). The log-rank test (Kaplan-Meier method) and cox-regression analysis was used to calculate BF-free survival.
Results: Between July 2005 and November 2020, a total of 137 patients ≤ 55 years (range 44-55 years old) were treated with… More >

Dylan M. Buller¹, Tara McLaughlin², Ilene Staff³, Kevin Pinto², Akshay Gangakhedkar², Joseph Tortora³, Guy Manetti⁴, Joseph R. Wagner²

Canadian Journal of Urology, Vol.29, No.1, pp. 10980-10985, 2022

Abstract Introduction: The current utility of MRI-fusion targeted biopsy as either an adjunct to or replacement for systematic template biopsy for the detection of clinically significant prostate cancer is disputed. The purpose of this study is to assess the current effectiveness of MRI-targeted versus systematic template prostate biopsies at two institutions and to consider possible underlying factors that could impact variability between detection rates in our patient population compared to others.
Materials and methods: A retrospective review from our prospectively maintained prostate cancer databases was conducted. Patients with prostate MRI lesions (PI-RADSv2) receiving concurrent systematic 12-core and MRI-fusion… More >

Joseph R. Wagner

Canadian Journal of Urology, Vol.29, No.1, pp. 10979-10979, 2022

Abstract This article has no abstract. More >

Irini Youssef^1,2, Michael Poch³, Natarajan Raghunand³, Julio Pow-Sang³, Peter A. S. Johnstone³

Canadian Journal of Urology, Vol.29, No.1, pp. 10976-10978, 2022

Abstract Introduction: To evaluate the use of preoperative magnetic resonance imaging (MRI) as a predictor of positive margins after radical prostatectomy (RP). This is important as such patients may benefit from postoperative radiotherapy. With the advent of preoperative MRI, we posited that pelvimetry could predict positive margins after RP in patients with less-than ideal pelvic dimensions undergoing robotic-assisted laparoscopic surgery.
Materials and methods: After IRB approval, data from patients undergoing RP at our center between 1/1/2018 and 12/31/2019 (n = 314) who had undergone prior prostate MRI imaging (n = 102) were analyzed. All RPs were performed using… More >

Paul H. Chung¹, Andrew Salib¹, Taylor Tidwell¹, Kaitlin Berry¹, Joon Yau Leong¹, Rosemary Frasso²

Canadian Journal of Urology, Vol.29, No.1, pp. 10969-10975, 2022

Abstract Introduction: Prior studies evaluating the efficacy of penile prostheses (PP) and intracavernosal injections (ICI) have focused predominantly on sexual function, not psychosocial health. We utilized the freelisting technique and the Self-Esteem and Relationship (SEAR) questionnaire to evaluate the impact of PP and ICI treatments on psychosocial functioning.
Materials and methods: IRB-approval was obtained to perform an evaluation of patients who underwent PP or ICI treatment for erectile dysfunction (ED). Using a modified freelisting approach, participants were asked to give three one-word responses to questions about sexual function and relationships. Participants also completed the SEAR questionnaire and results… More >