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  • Open Access

    ARTICLE

    Yuan-Cheng Fung : A Scientific Giant and a Kind Man

    Pin Tong1

    Molecular & Cellular Biomechanics, Vol.1, No.1, pp. 1-4, 2004, DOI:10.3970/mcb.2004.001.001

    Abstract This article has no abstract. More >

  • Open Access

    EDITORIAL

    Preface

    A.P.S. Selvadurai1

    CMES-Computer Modeling in Engineering & Sciences, Vol.48, No.3, 2009

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Condition Monitoring of Roller Bearing by K-Star Classifier and K-Nearest Neighborhood Classifier Using Sound Signal.

    Rahul Kumar Sharma*1, V. Sugumaran1, Hemantha Kumar2, Amarnath M3

    Structural Durability & Health Monitoring, Vol.11, No.1, pp. 1-16, 2017, DOI:10.3970/sdhm.2017.012.001

    Abstract Most of the machineries in small or large scale industry have rotating element supported by bearings for rigid support and accurate movement. For proper functioning of machinery, condition monitoring of the bearing is very important. In present study sound signal is used to continuously monitor bearing health as sound signals of rotating machineries carry dynamic information of components. There are numerous studies in literature that are reporting superiority of vibration signal of bearing fault diagnosis. However, there are very few studies done using sound signal. The cost associated with condition monitoring using sound signal (Microphone) is less than the cost… More >

  • Open Access

    ARTICLE

    Diabetic nephropathy, autophagy and proximal tubule protein endocytic transport: A potentially harmful relationship

    Maximiliano GIRAUD-BILLOUD1,2,*, Claudio M. FADER1,3, Rocío AGÜERO2, Fernando EZQUER4, Marcelo EZQUER4

    BIOCELL, Vol.42, No.2, pp. 35-40, 2018, DOI:10.32604/biocell.2018.07010

    Abstract Diabetic nephropathy (DN) is the most frequent cause of chronic renal failure. Until now, the pathophysiological mechanisms that determine its development and progression have not yet been elucidated. In the present study, we evaluate the role of autophagy at early stages of DN, induced in type 2 diabetes mellitus (T2DM) mouse, and its association with proximal tubule membrane endocytic receptors, megalin and cubilin. In T2DM animals we observed a tubule-interstitial injury with significantly increased levels of urinary GGT and ALP, but an absence of tubulointerstitial fibrosis. Kidney proximal tubule cells of T2DM animals showed autophagic vesicles larger than those observed… More >

  • Open Access

    ARTICLE

    Circumferential variation in mechanical characteristics of porcine descending aorta

    LINGFENG CHEN1,2,3, ZHIPENG GAO1,2,3, BAIMEI LIU1,2,3, YING LV1,2,3, MEIWEN AN1,2,3,*, JILING FENG4,*

    BIOCELL, Vol.42, No.1, pp. 25-34, 2018, DOI:10.32604/biocell.2018.06114

    Abstract Arterial characterization of healthy descending thoracic aorta (DTA) is indispensable in determining stress distributions across wall thickness and different regions that may be responsible for aorta inhomogeneous dilation, rupture, and dissection when aneurysm occurs. Few studies have shown the inhomogeneity of DTA along the aorta tree considering changes in circumferential direction. The present study aims to clarify the circumferential regional characterization of DTA. Porcine DTA tissues were tested according to region and orientation using uniaxial tension. For axial test, results show that the difference in circumferential direction was mainly in collagen fiber modulus, where the anterior collagen fiber modulus was… More >

  • Open Access

    ARTICLE

    Suspension state promotes extravasation of breast tumor cells by increasing integrin β1 expression

    Bingbing ZHANG1, 2, Ying ZHANG1, 2, Xiaomei ZHANG1, 2, Yonggang LV1, 2

    BIOCELL, Vol.42, No.1, pp. 17-24, 2018, DOI:10.32604/biocell.2018.06115

    Abstract Mechanical microenvironment can strongly affect the metastatic efficiency of circulating tumor cells. However, the effect of suspension state on their extravasation and the mechanisms involved are still unclear. To explore the influence of suspension state on extravasation (including adhesion, spreading and transendothelial migration) of breast tumor cells and its relevant molecular mechanism, MDA-MB-231 cells were cultured on poly (2-hydroxyethyl methacrylate) coated 6-well plates to minic the suspension state. Suspension state promoted adhesion, spreading and transendothelial migration of MDA-MB-231 cells to EAhy926 endothelial cells (ECs) monolayer under both the static condition and 0.5 dyne/cm2 flow shear stress (FSS). The number of… More >

  • Open Access

    ARTICLE

    Numerical modeling of shape-memory alloys in orthodontics

    F. Auricchio1, L. Petrini2, R. Pietrabissa3, E. Sacco4

    CMES-Computer Modeling in Engineering & Sciences, Vol.4, No.3&4, pp. 365-380, 2003, DOI:10.3970/cmes.2003.004.365

    Abstract Since 80’s many devices were developed to exploit the unique blend of mechanical and biocompatibility properties of shape memory alloys in orthodontic applications. It results in a high clinical effectiveness, but also in a spreading of technical knowledge on the properties of the single appliances. The goal of the present contribution is to contrast this sense of bewilderness and to prepare the basis for a simulationtool able to support the orthodontist choice. In particular a finite-element beam with a one-dimensional constitutive law, able to describe the SMA super elasticity and shape memory effect, is presented: it is shown how computer… More >

  • Open Access

    ARTICLE

    Platelet rich plasma (PRP) induces autophagy in osteoblast precursor 3T3-L1

    Sergio Andrés CARMINATI1,2, María Carolina BARBOSA2, Claudio Marcelo FADER1,2*

    BIOCELL, Vol.42, No.1, pp. 13-16, 2018, DOI:10.32604/biocell.2018.07008

    Abstract Autophagy is an essential cellular homeostatic mechanism by which intracellular components are delivered into the lysosomes for degradation and recycling. Autophagy has been related with a diversity of pathological or physiological dentary processes such as bone remodeling, skeletal aging, osteoclastogenesis, osteoblastogenesis and different types of oral cancer. Platelet-rich plasma (PRP), isolated from autologous blood, is a plasma preparation containing a higher concentration of platelets which contains numerous different growth factors and cytokines that activate several cellular signaling cascades. The purpose of this study is to investigate the effect of PRP on autophagy stimulation in both osteoblast precursor 3T3-L1 and non-related… More >

  • Open Access

    ARTICLE

    Feasible design for electricity generation from Chlorella vulgaris using convenient photosynthetic conditions

    Mahmoud MOUSTAFA1,2*, Tarek TAHA3, Mohamed ELNOUBY4, M.A. ABU-SAIED5, Ali SHATI1, Mohamed AL-KAHTANI1, Sulaiman ALRUMMAN1

    BIOCELL, Vol.42, No.1, pp. 7-12, 2018, DOI:10.32604/biocell.2018.07002

    Abstract Many recent studies are concerned with low cost, easy to handle and alternative renewable energy as a feasible solution for the upcoming crisis of energy shortage. Microalgae are unicellular entities the can only depend on CO2, water and solar power to cover their nutritional needs. The current study is concerned with using algal cells in a polymeric hydrogel, as a cheap source of energy for electricity generation. Chlorella vulgaris has been proved to be a promising algal species for electricity generation, as compared with Micractinium reisseri. PVA hydrogel has been used for the immobilization of both algal species in order… More >

  • Open Access

    ARTICLE

    Association between preterm birth risk and polymorphism and expression of the DNA repair genes OGG1 and APE1 in Saudi women

    Arwa Osama NEMER1, Mohammad Saud AL ANAZI2, Ramesa Shafi BHAT1*, Arjumand S. WARSY3, Zeneb A BABAY4, Mohammad H. ADDAR4, Jilani SHAIK2, Sooad AL-DAIHAN1

    BIOCELL, Vol.42, No.1, pp. 1-6, 2018, DOI:10.32604/biocell.2018.07005

    Abstract Genomic instability and mutations caused by increases in oxidative stress during pregnancy can damage the fetoplacental unit and can upshot preterm birth. Oxidative damage to DNA may possibly be involved in etiology of preterm birth (PTB) which can be repaired by DNA repair gene. In the present study, we assessed the association of base excision repair gene family by analyzing the association of single nucleotide polymorphisms and genes expression in 8-oxoguanine glycosylase-1 (OGG1) and apurinic-apyrimidinic endonuclease 1 (APE1) genes with risk of preterm birth in Saudi women. We analyzed genotypes of four single nucleotide polymorphisms (SNPs) (rs1052133, rs293795, rs2072668 and… More >

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