Lei Fang^*, Haiying Dong, Xiaofei Zhen, Shuaibing Li

Energy Engineering, Vol., , DOI:10.32604/ee.2023.029823

Abstract According to the multi-time-scale characteristics of power generation and demand-side response (DR) resources, as well as the improvement of prediction accuracy along with the approaching operating point, a rolling peak shaving optimization model consisting of three different time scales has been proposed. The proposed peak shaving optimization model considers not only the generation resources of two different response speeds but also the two different DR resources and determines each unit combination, generation power, and demand response strategy on different time scales so as to participate in the peaking of the power system by taking full advantage of the fast response… More >

Aisa Zulibiya^1,2,#, Jing Wen^3,#, Huiqing Yu^3,#, Xiaoming Chen³, Lei Xu³, Xiao Ma^1,2, Baojian Zhang^1,2,*

Congenital Heart Disease, Vol., , DOI:10.32604/chd.2023.047689

Abstract Background: Tetralogy of Fallot (TOF) is a very common cyanotic congenital heart disease. Endothelial-to-mesenchymal transition (EndoMT) is recognized as a physiological mechanism involved in embryonic heart development and endothelial formation. However, there is still a gap in the reports related to the mechanism of EndoMT development in TOF. Methods: First, transcriptomic data of single cell nuclei of TOF and Donor were obtained based on the Gene Expression Omnibus (GEO) database, and the data were normalized and clustered by dimensionality reduction using the Seurat package. Subsequently, differentially expressed genes (DEGs) between TOF and Donor were screened using the “FindMarkers” function, and… More >

XIAN ZHANG¹, ZHUANG ZHOU², JUNZHE WANG¹, MENGMENG HAN¹, HAN LIU¹, MEIRONG ZANG¹, JIANNING LIU¹, JIAPEI LU¹, JINQIAO ZHANG¹, GUOCHUAN ZHANG^2,*, LIXIA SUN^1,#,*

BIOCELL, Vol., , DOI:10.32604/biocell.2023.046640

Abstract Background: Prognosis of multiple myeloma (MM) patients with extramedullary disease (EMD) remains poor. T cell dysfunction and an immunosuppressive environment have been reported in the bone marrow (BM) of MM patients. However, the immunosuppressive microenvironment and immune checkpoint receptors (ICRs) on CD8 T cells in the EMD tissue of newly diagnosed MM (NDMM) patients have not been thoroughly studied. Methods: We investigated the expression levels of T cell immunoglobulin mucin-domain-containing-3 (TIM-3) and T-cell immunoglobulin and ITIM domain (TIGIT) on CD8 T cells and the expression of their ligands (Galectin-9 and CD155) on myeloma cells in EMD tissue of NDMM patients.… More > Graphic Abstract

ANWAR ALI^1,#, SREEKANTH REDDY OBIREDDY^2,#, WING-FU LAI^3,*

BIOCELL, Vol., , DOI:10.32604/biocell.2023.043839

Abstract Farnesol is a C15 isoprenyl alcohol generated from the hydrolysis of farnesyl diphosphate under the action of farnesol synthase in plants. Although this sesquiterpenoid alcohol has been exploited in a wide variety of industrial applications, serious discussions on the possible use of this agent in disease treatment have been scant until now. In this article, we review the current understanding of the physiological properties of farnesol and the potential use of the agent as a candidate for treatment development. In fact, since the turn of the last century, farnesol has been found not only to trigger apoptosis in tumor cells… More >

Hang Cui¹, Hongbo Ren^1,*, Qiong Wu^1,2, Hang Lv¹, Qifen Li^1,2, Weisheng Zhou³

Energy Engineering, Vol., , DOI:10.32604/ee.2023.047470

Abstract Cascading faults have been identified as the primary cause of multiple power outages in recent years. With the emergence of integrated energy systems (IES), the conventional approach to analyzing power grid cascading faults is no longer appropriate. A cascading fault analysis method considering multi-energy coupling characteristics is of vital importance. In this study, an innovative analysis method for cascading faults in integrated heat and electricity systems (IHES) is proposed. It considers the degradation characteristics of transmission and energy supply components in the system to address the impact of component aging on cascading faults. Firstly, degradation models for the current carrying… More >

Hanpeng Kou¹, Tianlong Bu¹, Leer Mao¹, Yihong Jiao^2,*, Chunming Liu²

Energy Engineering, Vol., , DOI:10.32604/ee.2023.045358

Abstract In order to play a positive role of decentralised wind power on-grid for voltage stability improvement and loss reduction of distribution network, a multi-objective two-stage decentralised wind power planning method is proposed in the paper, which takes into account the network loss correction for the extreme cold region. Firstly, an electro-thermal model is introduced to reflect the effect of temperature on conductor resistance and to correct the results of active network loss calculation; secondly, a two-stage multi-objective two-stage decentralised wind power siting and capacity allocation and reactive voltage optimisation control model is constructed to take account of the network loss… More >

Kwok Tai Chui^1,*, Brij B. Gupta^2,3,4,5,6,*, Varsha Arya^17,8,9, Miguel Torres-Ruiz¹⁰

CMC-Computers, Materials & Continua, Vol., , DOI:10.32604/cmc.2023.046762

Abstract The visions of Industry 4.0 and 5.0 have reinforced the industrial environment. They have also made artificial intelligence incorporated as a major facilitator. Diagnosing machine faults has become a solid foundation for automatically recognizing machine failure, and thus timely maintenance can ensure safe operations. Transfer learning is a promising solution that can enhance the machine fault diagnosis model by borrowing pre-trained knowledge from the source model and applying it to the target model, which typically involves two datasets. In response to the availability of multiple datasets, this paper proposes using selective and adaptive incremental transfer learning (SA-ITL), which fuses three… More >

HUI SUN, MASANORI KAWANO^*, TATSUYA IWASAKI, ICHIRO ITONAGA, YUTA KUBOTA, HIROSHI TSUMURA, KAZUHIRO TANAKA

Oncology Research, Vol., , DOI:10.32604/or.2023.044085

Abstract An important factor in the emergence and progression of osteosarcoma (OS) is the dysregulated expression of microRNAs (miRNAs). Transcription factor 7-like 1 (TCF7L1), a member of the T cell factor/lymphoid enhancer factor (TCF/LEF) transcription factor family, interacts with the Wnt signaling pathway regulator β-catenin and acts as a DNA-specific binding protein. This study sought to elucidate the impact of the interaction between miR-329-3p and TCF7L1 on the growth and apoptosis of OS and analyze the regulatory expression relationship between miRNA and mRNA in osteosarcoma cells using a variety of approaches. MiR329-3p was significantly downregulated, while TCF7L1 was considerably up-regulated in… More > Graphic Abstract

Antonio Pizzi^1,*, Marie-Pierre Laborie^2,3, Zeki Candan⁴

Journal of Renewable Materials, Vol., , DOI:10.32604/jrm.2023.046074

Abstract Condensed and hydrolysable tannins are non-toxic natural polyphenols that are a commercial commodity industrialized for tanning hides to obtain leather and for a growing number of other industrial applications mainly to substitute petroleum-based products. They are a definite class of sustainable materials of the forestry industry. They have been in operation for hundreds of years to manufacture leather and now for a growing number of applications in a variety of other industries, such as wood adhesives, metal coating, pharmaceutical/medical applications and several others. This review presents the main sources, either already or potentially commercial of this forestry by-materials, their industrial… More >

Fang Li^1,*, Juan Wu¹, Haiyong Yi², Lihong Wu², Lingyun Du¹, Yuan Zeng¹

FDMP-Fluid Dynamics & Materials Processing, Vol., , DOI:10.32604/fdmp.2023.043256

Abstract Methods for horizontal well spacing calculation in tight gas reservoirs are still adversely affected by the complexity of related control factors, such as strong reservoir heterogeneity and seepage mechanisms. In this study, the stress sensitivity and threshold pressure gradient of various types of reservoirs are quantitatively evaluated through reservoir seepage experiments. On the basis of these experiments, a numerical simulation model (based on the special seepage mechanism) and an inverse dynamic reserve algorithm (with different equivalent drainage areas) were developed. The well spacing ranges of Classes I, II, and III wells in the Q gas field are determined to be… More >