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  • Open Access

    REVIEW

    Fuzzing: Progress, Challenges, and Perspectives

    Zhenhua Yu1, Zhengqi Liu1, Xuya Cong1,*, Xiaobo Li2, Li Yin3

    CMC-Computers, Materials & Continua, Vol., , DOI:10.32604/cmc.2023.042361

    Abstract As one of the most effective techniques for finding software vulnerabilities, fuzzing has become a hot topic in software security. It feeds potentially syntactically or semantically malformed test data to a target program to mine vulnerabilities and crash the system. In recent years, considerable efforts have been dedicated by researchers and practitioners towards improving fuzzing, so there are more and more methods and forms, which make it difficult to have a comprehensive understanding of the technique. This paper conducts a thorough survey of fuzzing, focusing on its general process, classification, common application scenarios, and some state-of-the-art techniques that have been… More >

  • Open Access

    ARTICLE

    A Novel Energy and Communication Aware Scheduling on Green Cloud Computing

    Laila Almutairi1, Shabnam Mohamed Aslam2,*

    CMC-Computers, Materials & Continua, Vol., , DOI:10.32604/cmc.2023.040268

    Abstract The rapid growth of service-oriented and cloud computing has created large-scale data centres worldwide. Modern data centres’ operating costs mostly come from back-end cloud infrastructure and energy consumption. In cloud computing, extensive communication resources are required. Moreover, cloud applications require more bandwidth to transfer large amounts of data to satisfy end-user requirements. It is also essential that no communication source can cause congestion or bag loss owing to unnecessary switching buffers. This paper proposes a novel Energy and Communication (EC) aware scheduling (EC-scheduler) algorithm for green cloud computing, which optimizes data centre energy consumption and traffic load. The primary goal… More >

  • Open Access

    ARTICLE

    Combinational therapy with Myc decoy oligodeoxynucleotides encapsulated in nanocarrier and X-irradiation on breast cancer cells

    BEHROOZ JOHARI1,2,#,*, MILAD PARVINZAD LEILAN1,#, MAHMOUD GHARBAVI3, YOUSEF MORTAZAVI1, ALI SHARAFI2, HAMED REZAEEJAM4

    Oncology Research, Vol., , DOI:10.32604/or.2023.043576

    Abstract The Myc gene is the essential oncogene in triple-negative breast cancer (TNBC). This study investigates the synergistic effects of combining Myc decoy oligodeoxynucleotides-encapsulated niosomes-selenium hybrid nanocarriers with X-irradiation exposure on the MDA-MB-468 cell line. Decoy and scramble ODNs for Myc transcription factor were designed and synthesized based on promoter sequences of the Bcl2 gene. The nanocarriers were synthesized by loading Myc ODNs and selenium into chitosan (Chi-Se-DEC), which was then encapsulated in niosome-nanocarriers (NISM@Chi-Se-DEC). FT-IR, DLS, FESEM, and hemolysis tests were applied to confirm its characterization and physicochemical properties. Moreover, cellular uptake, cellular toxicity, apoptosis, cell cycle, and scratch repair… More > Graphic Abstract

    Combinational therapy with Myc decoy oligodeoxynucleotides encapsulated in nanocarrier and X-irradiation on breast cancer cells

  • Open Access

    ARTICLE

    Identification and validation of novel prognostic fatty acid metabolic gene signatures in colon adenocarcinoma through systematic approaches

    HENG ZHANG1,#, WENJING CHENG2,#, HAIBO ZHAO2, WEIDONG CHEN2, QIUJIE ZHANG2,*, QING-QING YU2,*

    Oncology Research, Vol., , DOI:10.32604/or.2023.043138

    Abstract Background: Colorectal cancer (CRC) belongs to the class of significantly malignant tumors found in humans. Recently, dysregulated fatty acid metabolism (FAM) has been a topic of attention due to its modulation in cancer, specifically CRC. However, the regulatory FAM pathways in CRC require comprehensive elucidation. Methods: The clinical and gene expression data of 175 fatty acid metabolic genes (FAMGs) linked with colon adenocarcinoma (COAD) and normal cornerstone genes were gathered through The Cancer Genome Atlas (TCGA)-COAD corroborating with the Molecular Signature Database v7.2 (MSigDB). Initially, crucial prognostic genes were selected by uni- and multi-variate Cox proportional regression analyses; then, depending… More >

  • Open Access

    ARTICLE

    Repair of Second-Generation Recycled Fine Aggregate of Waste Concrete from Freeze-Thaw Environment by Carbonation Treatment

    Jie Huang*, Rongbin Jiang, Xiaobo Sun, Yingyong Shuai

    Journal of Renewable Materials, Vol., , DOI:10.32604/jrm.2023.044232

    Abstract The reuse of waste recycled concrete from harsh environments has become a research hotspot in the field of construction. This study investigated the repair effect of carbonation treatment on second-generation recycled fine aggregate (SRFA) obtained from recycled fine aggregate concrete (RFAC) subjected to freeze-thaw (FT) cycles. Before and after carbonation, the properties of SRFA were evaluated. Carbonated second-generation recycled fine aggregate (CSRFA) at five substitution rates (0%, 25%, 50%, 75%, 100%) to replace SRFA was used to prepare carbonated second-generation recycled fine aggregate concrete (CSRFAC). The water absorption, porosity and mechanical properties of CSRFAC were tested, and its frost-resisting durability… More >

  • Open Access

    ARTICLE

    Aerodynamic Analysis and Optimization of Pantograph Streamline Fairing for High-Speed Trains

    Xiang Kan1, Yan Li2, Tian Li1,*, Jiye Zhang1

    FDMP-Fluid Dynamics & Materials Processing, Vol., , DOI:10.32604/fdmp.2023.044050

    Abstract A pantograph serves as a vital device for the collection of electricity in trains. However, its aerodynamic resistance can limit the train’s running speed. As installing fairings around the pantograph is known to effectively reduce the resistance, in this study, different fairing lengths are considered and the related aerodynamic performances of pantograph are assessed. In particular, this is accomplished through numerical simulations based on the k-ω Shear Stress Transport (SST) two-equation turbulence model. The results indicate that the fairing diminishes the direct impact of high-speed airflow on the pantograph, thereby reducing its aerodynamic resistance. However, it also induces interferences in… More >

  • Open Access

    ARTICLE

    Performance Characterization of CR/PU Asphalt for Potential Application in Assembled Fast-Repairing Engineering

    Hong Pang1, Ao Lu1, Ming Xiong1, Chen Chen1, Xian Cao1, Xiong Xu2,3,*, Jing Wang1

    FDMP-Fluid Dynamics & Materials Processing, Vol., , DOI:10.32604/fdmp.2023.044000

    Abstract Conventional repairing methods for asphalt pavement have some inconveniences, such as insufficient strength, and are typically time-consuming. To address these issues, this study proposes a new technological method to design and prepare a high-performance assembled asphalt concrete block for fast repair of the potholes. A series of composite modified asphalt binders with 10% crumb rubber (CR) and different dosages (0%, 1%, 3%, 5%) of polyurethane (PU) are examined to determine the optimized binder. Subsequently, the corresponding asphalt mixtures are prepared for further comparison and assessment of engineering properties, such as moistureinduced damage, high-temperature deformation, and low-temperature cracking characteristics. The test… More >

  • Open Access

    ARTICLE

    Smoothed-Particle Hydrodynamics Simulation of Ship Motion and Tank Sloshing under the Effect of Regular Waves

    Mingming Zhao, Jialong Jiao*

    FDMP-Fluid Dynamics & Materials Processing, Vol., , DOI:10.32604/fdmp.2023.043744

    Abstract Predicting the response of liquefied natural gas (LNG) contained in vessels subjected to external waves is extremely important to ensure the safety of the transportation process. In this study, the coupled behavior due to ship motion and liquid tank sloshing has been simulated by the Smoothed-Particle Hydrodynamics (SPH) method. Firstly, the sloshing flow in a rectangular tank was simulated and the related loads were analyzed to verify and validate the accuracy of the present SPH solver. Then, a three-dimensional simplified LNG carrier model, including two prismatic liquid tanks and a wave tank, was introduced. Different conditions were examined corresponding to… More >

  • Open Access

    ARTICLE

    Numerical Simulation of Asphaltene Precipitation and Deposition during Natural Gas and CO2 Injection

    Shasha Feng*, Yi Liao, Weixin Liu, Jianwen Dai, Mingying Xie, Li Li

    FDMP-Fluid Dynamics & Materials Processing, Vol., , DOI:10.32604/fdmp.2023.041825

    Abstract Asphaltene deposition is a significant problem during gas injection processes, as it can block the porous medium, the wellbore, and the involved facilities, significantly impacting reservoir productivity and ultimate oil recovery. Only a few studies have investigated the numerical modeling of this potential effect in porous media. This study focuses on asphaltene deposition due to natural gas and CO2 injection. Predictions of the effect of gas injection on asphaltene deposition behavior have been made using a 3D numerical simulation model. The results indicate that the injection of natural gas exacerbates asphaltene deposition, leading to a significant reduction in permeability near… More >

  • Open Access

    ARTICLE

    Influence of Brownian Motion, Thermophoresis and Magnetic Effects on a Fluid Containing Nanoparticles Flowing over a Stretchable Cylinder

    Aaqib Majeed1,*, Ahmad Zeeshan2

    FDMP-Fluid Dynamics & Materials Processing, Vol., , DOI:10.32604/fdmp.2023.028716

    Abstract The influence of Brownian motion and thermophoresis on a fluid containing nanoparticles flowing over a stretchable cylinder is examined. The classical Navier-Stokes equations are considered in a porous frame. In addition, the Lorentz force is taken into account. The controlling coupled nonlinear partial differential equations are transformed into a system of first order ordinary differential equations by means of a similarity transformation. The resulting system of equations is solved by employing a shooting approach properly implemented in MATLAB. The evolution of the boundary layer and the growing velocity is shown graphically together with the related profiles of concentration and temperature.… More >

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