Xingchen Zhu¹, Haohan Zhao^2,*, Wencan Li^3,*, Zixu Wang¹

International Journal of Mental Health Promotion, DOI:10.32604/ijmhp.2026.078033

Abstract Backgrounds: Adolescent psychological well-being has become a pressing global concern, with rising levels of emotional distress among youth. Although prior research highlights the positive influence of teacher–student relationships, the underlying mechanisms—particularly the roles of school belonging, moral disengagement, and growth mindset—remain insufficiently understood. This study investigates the associations between teacher-student relationship quality and adolescent psychological well-being, examining school belonging and moral disengagement as potential mediators, and growth mindset as a moderator of these relationships. Methods: A total of 785 adolescents were recruited from six schools across Shanghai and Liaoning Province, China. Participants completed validated measures of… More >

Chae-Young Lee¹, Yun-Jung Choi^2,*

International Journal of Mental Health Promotion, DOI:10.32604/ijmhp.2026.077116

Abstract Background: Adolescent suicide remains a pressing public health concern in South Korea and worldwide, ranking as one of the leading causes of death among youth. Identifying modifiable risk and protective factors is critical for prevention strategies. Physical activity has been suggested as one such factor due to its potential mental health benefits. This study aimed to examine whether associations between physical activity and suicidality differ by activity type and by stage of suicidal behavior, distinguishing suicidal ideation, planning, and attempts among Korean adolescents. Methods: This cross-sectional secondary analysis used data from the 20th Korea Youth Risk… More >

Shuqing Wang, Xiuqiu Liu, Siqi Yu, Meili Zheng, Shuhua Wei^*

International Journal of Mental Health Promotion, DOI:10.32604/ijmhp.2026.076977

Abstract Background: While parenting is crucial for adolescents’ academic adjustment, few studies have examined how parental autonomy support affects academic burnout or the underlying psychological processes. This study examined the sequential mediating roles of growth mindset and self-esteem in the association between parental autonomy support and academic burnout, using both variable-centered and person-centered approaches. Methods: A total of 1032 Chinese junior and senior high school students were recruited through cluster sampling. Using self-report questionnaires, participants were assessed on parental autonomy support, growth mindset, self-esteem, and academic burnout. Data were analyzed using mediation modeling and latent profile analysis. Results:… More >

Xing-Guo Li^1,2,3,#, Lu-Kai Wang^4,#, Fu-Ming Tsai⁵, Hsueh-Chun Wang^1,*

BIOCELL, DOI:10.32604/biocell.2026.075492

Abstract Itaconate, produced by aconitate decarboxylase 1 (ACOD1, also known as IRG1), acts as a key immunometabolite that inhibits succinate dehydrogenase (SDH) and can engage reduction-oxidation (redox)-sensitive signaling programs. This review summarizes the emerging, context-dependent roles of the ACOD1-itaconate axis in cancer, while critically distinguishing between the effects of endogenous itaconate and its cell-permeable derivatives. In tumor cells, endogenous ACOD1 expression or uptake via solute carrier family 13 member 3 (SLC13A3) alters oxidative phosphorylation and glycolysis. In the tumor microenvironment, myeloid-derived itaconate contributes to immune tolerance by reducing dendritic-cell cross-priming and limiting CD8⁺ T-cell metabolic activity. Moreover, More >

Francisco Raúl Borzone^1,2,*, María Belén Giorello¹, Agustina Freire³, Leandro Marcelo Martinez⁴, Leonardo Feldman⁵, Federico Dimase⁶, Pablo Evelson³, Irene Larripa⁷, Emilio Batagelj⁸, Marcela Beatriz González Cid⁹, Norma Alejandra Chasseing^1,*

Oncology Research, DOI:10.32604/or.2026.074321

Abstract Backgrounds: Breast cancer metastasis remains the leading cause of mortality and frequently targets the bone. Breast cancer cells release soluble factors and extracellular vesicles that disrupt bone marrow (BM)/bone homeostasis, promoting osteoclastogenesis and the accumulation of senescent cells. In line with updated cancer hallmarks, senescent mesenchymal stem/ stromal cells (MSCs), osteoblasts, and osteocytes contribute to remodeling of the BM microenvironment, thereby favoring pre-metastatic niche (PMN) formation and subsequent bone metastasis. We previously demonstrated that untreated stage III-B breast cancer patients (BCPs) exhibit increased oxidative stress and elevated reactive oxygen species (ROS) levels, accompanied by senescent… More > Graphic Abstract

Awatif Rashed Z. Almotairy^1,2, Eman Fayad³, Fatimah Hadadi⁴, Ahmad F. Alhomodi⁵, Dalal Nasser Binjawhar⁶, Hanadi A. Katouah⁷, Bassma H. Elwakil^8,*, Keshav Raj Paudel^9,10,*, Mostafa El-Khatib¹¹

Oncology Research, DOI:10.32604/or.2025.070645

Abstract Objectives: Prostate cancer cells often develop mechanisms to evade conventional therapies. Nanomedicine offers the potential for targeted drug delivery, improved tumor accumulation, and reduced systemic toxicity. This study biosynthesizes silver nanoparticles (NPP/AgONPs) functionalized with propolis, evaluates their antibacterial efficacy against uropathogenic strains of Escherichia coli (E. coli), and assesses their cytotoxic effect on cancer cell proliferation using the PC-3, human prostate epithelial cell line. Methods: The synthesized NPP/AgONPs physiochemical parameters were characterized, followed by in vitro assays to evaluate their antibacterial activity against multiple uropathogenic E. coli strains; determining the cytotoxicity against HPrEC and PC-3 cells by measuring cytotoxicity (CC₅₀)… More >

Wanqing Lin^1,2,*, Mohd Azrin Mohd Nasir¹, Suzila Binti Ismail¹

Journal of Psychology in Africa, DOI:10.32604/jpa.2026.073231

Abstract This systematic review synthesizes empirical research on external risk factors for adolescent smartphone addiction. Scopus and Web of Science were searched for English peer-reviewed empirical articles from 2008 onward; 28 met inclusion criteria (excluding non-adolescents, generic internet addiction, non-empirical work, or non-English). Thematic synthesis organized findings into three external risk domains—family, school, and peers—considering cultural/contextual mechanisms. Family dynamics (parental phubbing, harsh parenting, dysfunction), school stressors, and adverse peer relationships were identified as accumulating, direct and indirect contributors to smartphone addiction. These operate within a techno-ecological framework, where digital technologies amplify vulnerabilities and create new pathways More >

Ying Zhu^1,2, Minghui Hu³, Shengxu Wang^1,2, Xiaoliang Dong^3,*, Xuewen Xiao^1,2, Richeng Liu³, Meng Wang^1,2, Zheng Yuan³

CMES-Computer Modeling in Engineering & Sciences, DOI:10.32604/cmes.2026.076381

Abstract In-situ enlargement of super-large-span tunnels can intensify excavation-induced unloading in the surrounding rock, increasing deformation demand and failure risk during construction. This study combines laboratory model tests with FLAC3D simulations to evaluate the stabilizing role of prestressed anchor cables and to establish an energy-balance framework for support optimization. Comparative model tests of existing and enlarged tunnel sections, with and without anchors, show that reinforcement increases load-carrying capacity, reduces displacement, and confines damage to more localized zones. The numerical simulations reproduce displacement fields, shear-strain localization, and plastic-zone evolution with good agreement against the experimental observations. The energy More >

Hitesh Mohapatra^*

CMC-Computers, Materials & Continua, DOI:10.32604/cmc.2026.076726

Abstract This review examines current approaches to real-time decision-making and task optimization in Internet of Things systems through the application of machine learning models deployed at the network edge. Existing literature shows that edge-based distributed intelligence reduces cloud dependency. It addresses transmission latency, device energy use, and bandwidth limits. Recent optimization strategies employ dynamic task offloading mechanisms to determine optimal workload placement across local devices and edge servers without centralized coordination. Empirical findings from the literature indicate performance improvements with latency reductions of approximately 32.8% and energy efficiency gains of 27.4% compared to conventional cloud-centric models.… More >

Ying Yao¹, Le Tian^1,2,3, Yuxiang Hu^1,2,3,*, Pengshuai Cui^1,2,3

CMC-Computers, Materials & Continua, DOI:10.32604/cmc.2026.075747

Abstract In the process of programmable networks simplifying network management and increasing network flexibility through custom packet behavior, security incidents caused by human logic errors are seriously threatening their safe operation, robust verification methods are required to ensure their correctness. As one of the formal methods, symbolic execution offers a viable approach for verifying programmable networks by systematically exploring all possible paths within a program. However, its application in this field encounters scalability issues due to path explosion and complex constraint-solving. Therefore, in this paper, we propose NetVerifier, a scalable verification system for programmable networks. To… More >