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  • Open Access

    ARTICLE

    IQGAP3 promotes the progression of glioma as an immune and prognostic marker

    XIAOFENG GAO1,2,3,4, JUANJUAN GE3, XUZHENG GAO1,3, NA MEI1,3, YANTING SU3, SHIGANG SHAN3, WENBIN QIAN3, JIANGHENG GUAN5, ZHENWANG ZHANG1,3,*, LONG WANG2,3,4,*

    Oncology Research, Vol., , DOI:10.32604/or.2023.046712

    Abstract Background: IQGAP3 plays a crucial role in regulating cell proliferation, division, and cytoskeletal organization. Abnormal expression of IQGAP3 has been linked to various tumors, but its function in glioma is not well understood. Methods: Various methods, including genetic differential analysis, single-cell analysis, ROC curve analysis, Cox regression, Kaplan-Meier analysis, and enrichment analysis, were employed to analyze the expression patterns, diagnostic potential, prognostic implications, and biological processes involving IQGAP3 in normal and tumor tissues. The impact of IQGAP3 on immune infiltration and the immune microenvironment in gliomas was evaluated using immunofluorescence. Additionally, the cBioPortal database was used to analyze copy number… More > Graphic Abstract

    IQGAP3 promotes the progression of glioma as an immune and prognostic marker

  • Open Access

    ARTICLE

    Multi-cohort comprehensive analysis unveiling the clinical value and therapeutic effect of GNAL in glioma

    ZHEN LIU1,#, LIANGWANG YANG2,#, ZHENGXING XIE1, HUI YU3, TIANYI GU3, DAOMING SHI4, NING CAI1,*, SHENGHUA ZHUO2,*

    Oncology Research, Vol., , DOI:10.32604/or.2024.045769

    Abstract Clinical data indicates that glioma patients have poor treatment outcomes and clinical prognosis. The role of olfactory signaling pathway-related genes (OSPRGs) in glioma has not been fully elucidated. In this study, we aimed to investigate the role and relationship between OSPRGs and glioma. Univariate and multivariate Cox regression analyses were performed to assess the relationship between OSPRGs and the overall survival of glioma based on public cohorts, and the target gene (G Protein Subunit Alpha L, GNAL) was screened. The association of GNAL expression with clinicopathological characteristics, gene mutation landscape, tumor immune microenvironment (TIME), deoxyribonucleic acid (DNA) methylation, and naris-occlusion… More >

  • Open Access

    ARTICLE

    The Relationship between Father-Love Absence and Loneliness: Based on the Perspective of the Social Functionalist Theory and the Social Needs Theory

    Yaping Zhou1,2,5,#, He Zhong3,#, Xiaojun Li4,*, Yanhui Xiang1,2,5,*

    International Journal of Mental Health Promotion, Vol., , DOI:10.32604/ijmhp.2023.046598

    Abstract Fathers play an important role in adolescents’ development, which is significant for their development and influences their mental health, including feeling of loneliness. However, the effects and mechanisms of father-love absence on individual loneliness are not clear. Based on the social functionalist theory and the social needs theory, this study examines the influence of individual father-love absence on loneliness and its underlying mechanisms. A questionnaire survey was administered to 319 junior high school students and 1,476 high school students. The results showed that adolescents with father-love absence had higher levels of loneliness, and that father-love absence affected loneliness levels through… More >

  • Open Access

    ARTICLE

    A New Flower Pollination Algorithm Strategy for MPPT of Partially Shaded Photovoltaic Arrays

    Muhannad J. Alshareef*

    Intelligent Automation & Soft Computing, Vol., , DOI:10.32604/iasc.2023.046722

    Abstract Photovoltaic (PV) systems utilize maximum power point tracking (MPPT) controllers to optimize power output amidst varying environmental conditions. However, the presence of multiple peaks resulting from partial shading poses a challenge to the tracking operation. Under partial shade conditions, the global maximum power point (GMPP) may be missed by most traditional maximum power point tracker. The flower pollination algorithm (FPA) and particle swarm optimization (PSO) are two examples of metaheuristic techniques that can be used to solve the issue of failing to track the GMPP. This paper discusses and resolves all issues associated with using the standard FPA method as… More >

  • Open Access

    ARTICLE

    A Study of the Effect of the Miller Cycle on the Combustion of a Supercharged Marine Diesel Engine

    Lingjie Zhao, Cong Li*

    Energy Engineering, Vol., , DOI:10.32604/ee.2024.046918

    Abstract The Miller cycle is a program that effectively reduces NOx emissions from marine diesel engines by lowering the maximum combustion temperature in the cylinder, thereby reducing NOx emissions. To effectively investigate the impact of Miller cycle optimum combustion performance and emission capability under high load conditions, this study will perform a one-dimensional simulation of the performance of a marine diesel engine, as well as a threedimensional simulation of the combustion in the cylinder. A 6-cylinder four-stroke single-stage supercharged diesel engine is taken as the research object. The chassis dynamometer and other related equipment are used to build the test system,… More >

  • Open Access

    ARTICLE

    Weather-Driven Solar Power Forecasting Using D-Informer: Enhancing Predictions with Climate Variables

    Chenglian Ma1, Rui Han1, Zhao An2,*, Tianyu Hu2, Meizhu Jin2

    Energy Engineering, Vol., , DOI:10.32604/ee.2024.046644

    Abstract Precise forecasting of solar power is crucial for the development of sustainable energy systems. Contemporary forecasting approaches often fail to adequately consider the crucial role of weather factors in photovoltaic (PV) power generation and encounter issues such as gradient explosion or disappearance when dealing with extensive time-series data. To overcome these challenges, this research presents a cutting-edge, multi-stage forecasting method called D-Informer. This method skillfully merges the differential transformation algorithm with the Informer model, leveraging a detailed array of meteorological variables and historical PV power generation records. The D-Informer model exhibits remarkable superiority over competing models across multiple performance metrics,… More > Graphic Abstract

    Weather-Driven Solar Power Forecasting Using D-Informer: Enhancing Predictions with Climate Variables

  • Open Access

    ARTICLE

    A Compact UHF Antenna Based on Hilbert Fractal Elements and a Serpentine Arrangement for Detecting Partial Discharge

    Xiang Lin1,*, Jian Fang1, Ming Zhang1, Kuang Yin1, Yan Tian1, Yingfei Guo2, Qianggang Wang2

    Energy Engineering, Vol., , DOI:10.32604/ee.2024.046861

    Abstract Efforts to protect electric power systems from faults have commonly relied on the use of ultra-high frequency (UHF) antennas for detecting partial discharge (PD) as a common precursor to faults. However, the effectiveness of existing UHF antennas suffers from a number of challenges such as limited bandwidth, relatively large physical size, and low detection sensitivity. The present study addresses these issues by proposing a compact microstrip patch antenna with fixed dimensions of 100 mm × 100 mm × 1.6 mm. The results of computations yield an optimized antenna design consisting of 2nd-order Hilbert fractal units positioned within a four-layer serpentine… More > Graphic Abstract

    A Compact UHF Antenna Based on Hilbert Fractal Elements and a Serpentine Arrangement for Detecting Partial Discharge

  • Open Access

    REVIEW

    Saddlepoint Approximation Method in Reliability Analysis: A Review

    Debiao Meng1,2,*, Yipeng Guo1,2, Yihe Xu3, Shiyuan Yang1,2,*, Yongqiang Guo4, Lidong Pan4, Xinkai Guo2

    CMES-Computer Modeling in Engineering & Sciences, Vol., , DOI:10.32604/cmes.2024.047507

    Abstract The escalating need for reliability analysis (RA) and reliability-based design optimization (RBDO) within engineering challenges has prompted the advancement of saddlepoint approximation methods (SAM) tailored for such problems. This article offers a detailed overview of the general SAM and summarizes the method characteristics first. Subsequently, recent enhancements in the SAM theoretical framework are assessed. Notably, the mean value first-order saddlepoint approximation (MVFOSA) bears resemblance to the conceptual framework of the mean value second-order saddlepoint approximation (MVSOSA); the latter serves as an auxiliary approach to the former. Their distinction is rooted in the varying expansion orders of the performance function as… More >

  • Open Access

    ARTICLE

    An Empirical Study on the Effectiveness of Adversarial Examples in Malware Detection

    Younghoon Ban, Myeonghyun Kim, Haehyun Cho*

    CMES-Computer Modeling in Engineering & Sciences, Vol., , DOI:10.32604/cmes.2023.046658

    Abstract Antivirus vendors and the research community employ Machine Learning (ML) or Deep Learning (DL)-based static analysis techniques for efficient identification of new threats, given the continual emergence of novel malware variants. On the other hand, numerous researchers have reported that Adversarial Examples (AEs), generated by manipulating previously detected malware, can successfully evade ML/DL-based classifiers. Commercial antivirus systems, in particular, have been identified as vulnerable to such AEs. This paper firstly focuses on conducting black-box attacks to circumvent ML/DL-based malware classifiers. Our attack method utilizes seven different perturbations, including Overlay Append, Section Append, and Break Checksum, capitalizing on the ambiguities present… More >

  • Open Access

    REVIEW

    A Comprehensive Survey for Privacy-Preserving Biometrics: Recent Approaches, Challenges, and Future Directions

    Shahriar Md Arman1, Tao Yang1,*, Shahadat Shahed2, Alanoud Al Mazroa3, Afraa Attiah4, Linda Mohaisen4

    CMC-Computers, Materials & Continua, Vol., , DOI:10.32604/cmc.2024.047870

    Abstract The rapid growth of smart technologies and services has intensified the challenges surrounding identity authentication techniques. Biometric credentials are increasingly being used for verification due to their advantages over traditional methods, making it crucial to safeguard the privacy of people’s biometric data in various scenarios. This paper offers an in-depth exploration for privacy-preserving techniques and potential threats to biometric systems. It proposes a noble and thorough taxonomy survey for privacy-preserving techniques, as well as a systematic framework for categorizing the field’s existing literature. We review the state-of-the-art methods and address their advantages and limitations in the context of various biometric… More >

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