Feasibility of water vapor thermal therapy for treating lower urinary tract symptoms in men with localized prostate cancer on active surveillance: a case series

Mustufa Babar^1,*, Farooz Babar², Noah Hawks-Ladds³, Justin Loloi⁴, Michael Ciatto⁵
1 Hackensack Meridian Health, Palisades Medical Center, North Bergen, NJ 07047, USA
2 St. George’s University School of Medicine, University Centre, Grenada, P.O. Box 7, West Indies
3 Albert Einstein College of Medicine, Bronx, NY 10461, USA
4 Department of Urology, Montefiore Medical Center, Bronx, NY 10467, USA
5 DSS Urology, Queens Village, NY 11427, USA
* Corresponding Author: Mustufa Babar. Email: email

Canadian Journal of Urology https://doi.org/10.32604/cju.2025.066654

Received 14 April 2025; Accepted 22 August 2025; Published online 15 September 2025

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Abstract

Background: Prostate cancer is a common malignancy, with many men on active surveillance for localized, low-risk disease also experiencing lower urinary tract symptoms (LUTS) from benign prostatic hyperplasia (BPH). Water Vapor Thermal Therapy (WVTT) is a minimally invasive BPH treatment, but its safety and efficacy in this setting are unclear. Case Description: We report three men with localized PCa on active surveillance who underwent WVTT for LUTS. Conclusions: WVTT appears safe and potentially effective in treating LUTS, especially in those with lower-risk disease and smaller prostate volumes. Further research is needed to confirm safety, efficacy, and optimal patient selection.