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Cell adhesion in renal tubular epithelial cells: Biochemistry, biophysics or both

CLAIRE ELIZABETH HILLS, ELEFTHERIOS SIAMANTOURAS, PAUL EDWARD SQUIRES*

Diabetes, Metabolism & Inflammation Group, School of Life Sciences, Joseph Banks Laboratories, University of Lincoln, Lincoln, LN6 7DL, UK

* Corresponding Author: PAUL EDWARD SQUIRES. Email: email

BIOCELL 2022, 46(4), 937-940. https://doi.org/10.32604/biocell.2022.018414

Abstract

Changes in cell-cell and cell-substrate adhesion markers are increasingly used to characterize disease onset and progression. However, these relationships depend on both the biochemical and molecular association between cells and between cells and their extracellular matrix, as well as the biophysical and mechanical properties orchestrated by cytoskeletal, membrane and matrix components. To fully appreciate the role of cell adhesion when determining normal physiology and the impact of disease on cellular function, it is important to consider both biochemical and biophysical attributes of the system being investigated. In this short viewpoint we reflect on our experiences assessing cell-cell and/or cell-matrix interactions in renal tubular epithelial cells.

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APA Style
HILLS, C.E., SIAMANTOURAS, E., SQUIRES, P.E. (2022). Cell adhesion in renal tubular epithelial cells: biochemistry, biophysics or both. BIOCELL, 46(4), 937-940. https://doi.org/10.32604/biocell.2022.018414
Vancouver Style
HILLS CE, SIAMANTOURAS E, SQUIRES PE. Cell adhesion in renal tubular epithelial cells: biochemistry, biophysics or both. BIOCELL . 2022;46(4):937-940 https://doi.org/10.32604/biocell.2022.018414
IEEE Style
C.E. HILLS, E. SIAMANTOURAS, and P.E. SQUIRES "Cell adhesion in renal tubular epithelial cells: Biochemistry, biophysics or both," BIOCELL , vol. 46, no. 4, pp. 937-940. 2022. https://doi.org/10.32604/biocell.2022.018414



cc This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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