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Protein-mediated interactions in the dynamic regulation of acute inflammation

RYAN STARK*

Department of Pediatric Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232-9075, USA

* Corresponding Author: RYAN STARK. Email: email

(This article belongs to the Special Issue: Biochemical and Epigenetics Changes in Health and Disease)

BIOCELL 2023, 47(6), 1191-1198. https://doi.org/10.32604/biocell.2023.027838

Abstract

Protein-mediated interactions are the fundamental mechanism through which cells regulate health and disease. These interactions require physical contact between proteins and their respective targets of interest. These targets include not only other proteins but also nucleic acids and other important molecules as well. These proteins are often involved in multibody complexes that work dynamically to regulate cellular health and function. Various techniques have been adapted to study these important interactions, such as affinity-based assays, mass spectrometry, and fluorescent detection. The application of these techniques has led to a greater understanding of how protein interactions are responsible for both the instigation and resolution of acute inflammatory diseases. These pursuits aim to provide opportunities to target specific protein interactions to alleviate acute inflammation.

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Cite This Article

APA Style
STARK, R. (2023). Protein-mediated interactions in the dynamic regulation of acute inflammation. BIOCELL, 47(6), 1191-1198. https://doi.org/10.32604/biocell.2023.027838
Vancouver Style
STARK R. Protein-mediated interactions in the dynamic regulation of acute inflammation. BIOCELL . 2023;47(6):1191-1198 https://doi.org/10.32604/biocell.2023.027838
IEEE Style
R. STARK, "Protein-mediated interactions in the dynamic regulation of acute inflammation," BIOCELL , vol. 47, no. 6, pp. 1191-1198. 2023. https://doi.org/10.32604/biocell.2023.027838



cc This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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