Open Access
ARTICLE
Morphological Evaluation of PLA/Soybean Oil Epoxidized Acrylate Three-Dimensional Scaffold in Bone Tissue Engineering
Mahmood Hameed Majeed*, Nabeel Kadhem Abd Alsaheb
Department of Biomedical Engineering, Al Nahrain University, Al Jadriya Bridge, Baghdad, 64074, Iraq
* Corresponding Authors: Mahmood Hameed Majeed. Email: ;
Journal of Renewable Materials 2022, 10(9), 2391-2408. https://doi.org/10.32604/jrm.2022.019887
Received 22 October 2021; Accepted 14 January 2022; Issue published 30 May 2022
Abstract
Tissue engineering’s main goal is to regenerate or replace tissues or organs that have been destroyed by disease,
injury, or congenital disabilities. Tissue engineering now uses artificial supporting structures called scaffolds to
restore damaged tissues and organs. These are utilized to attach the right cells and then grow them. Rapid prototyping appears to be the most promising technology due to its high level of precision and control. Bone tissue
replacement “scaffolding” is a common theme discussed in this article. The fused deposition technique was used
to construct our scaffold, and a polymer called polylactic acids and soybean oil resin were used to construct our
samples. The samples were then divided into two groups; the first group was left without immersion in the simulated body fluid and served as a control for comparison. The second group was immersed in the simulated body
fluid. The results of the Field Emission Scanning Electron Microscope (FESEM), Energy Dispersive X-ray Spectroscopy (EDX) and X-ray diffraction (XRD) were utilized to interpret the surface attachment to ions, elements, and
compounds, giving us a new perspective on scaffold architecture. In this study, an innovative method has been
used to print therapeutic scaffold that combines fused deposition three-dimensional printing with ultraviolet curing to create a high-quality biodegradable polymeric scaffold. Finally, the results demonstrate that adding soybean
oil resin to the PLA increased ion attachment to the surface while also attracting tricalcium phosphate formation
on the surface of the scaffold, which is highly promising in bone tissue replacement. In conclusion, the soybean oil
resin, which is new in the field of bone tissue engineering, shows magnificent characteristics and is a good replacement biopolymer that replaces many ceramic and polymeric materials used in this field that have poor morphological characteristics.
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Cite This Article
Majeed, M. H., Kadhem, N. (2022). Morphological Evaluation of PLA/Soybean Oil Epoxidized Acrylate Three-Dimensional Scaffold in Bone Tissue Engineering.
Journal of Renewable Materials, 10(9), 2391–2408. https://doi.org/10.32604/jrm.2022.019887