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Antibacterial activity of Falkenbergia hillebrandii (Born) from the Indian coast against human pathogens

Manilal1 A, S Sujith2, J Selvin3, C Shakir4, G Seghal Kiran5
1-4 Department of Microbiology, Bharathidasan University, Tiruchirappalli – 620 024, India.
5 Department of Biotechnology, Bharathidasan University, Tiruchirappalli – 620 024, India.
Address Correspondence to: Joseph Selvin, Department of Microbiology, Bharathidasan University, Tiruchirappalli 620024 India. Tel: +91-431-2407082. Fax: +91-431-2407084. e-mail: selvinj@rediffmail.com, alternate e-mail: seeshegal@yahoo.com.in.

Phyton-International Journal of Experimental Botany 2009, 78(all), 161-166. https://doi.org/10.32604/phyton.2009.78.161

Abstract

The antibacterial property of the red algae, Falkenbergia hillebrandii (Born) collected from the southwest coast of India (Indian Ocean) was evaluated against three multidrug resistant human pathogens. Four different solvents: ethyl acetate, dichloromethane, methanol and phosphate buffer saline (PBS) were used with this purpose. Dried samples extracted with methanol showed broadest and highest antimicrobial activity when compared to other solvents. However, PBS extract showed no antibacterial activity. The highly active compounds red alga, F. hillebrandii were fractionated and purified using different chromatographic systems, including reverse phase HPLC and GCMS. The analysis revealed that the most abundant metabolite was the oleic acid (51.33%) followed by n-hexadecanoic acid (42%).

Keywords

Antimicrobial activity, F. hillebrandii, Multidrug resistant human pathogens, Methanolic extract, Bioactive compounds.

Cite This Article

, M., Selvin, J., Shakir, C., Kiran, G. S. (2009). Antibacterial activity of Falkenbergia hillebrandii (Born) from the Indian coast against human pathogens. Phyton-International Journal of Experimental Botany, 78(all), 161–166.

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This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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