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  • Open Access

    ARTICLE

    Crashworthiness Design and Multi-Objective Optimization of Bionic Thin-Walled Hybrid Tube Structures

    Pingfan Li, Jiumei Xiao*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 999-1016, 2024, DOI:10.32604/cmes.2023.044059

    Abstract Thin-walled structures are widely used in cars due to their lightweight construction and energy-absorbing properties. However, issues such as high initial stress and low energy-absorbing efficiency arise. This study proposes a novel energy-absorbing structure in which a straight tube is combined with a conical tube and a bamboo-inspired bulkhead structure is introduced. This configuration allows the conical tube to flip outward first and then fold together with the straight tube. This deformation mode absorbs more energy and less peak force than the conical tube sinking and flipping inward. Through finite element numerical simulation, the specific energy absorption capacity of the… More >

  • Open Access

    ARTICLE

    Absent in melanoma 2 attenuates proliferation and migration and promotes apoptosis of human colorectal cancer cells by activating P38MAPK signaling pathway

    ZHI ZHANG1,#, XIAOSONG LI1,2,#, YING ZHANG1,2,#, HAO ZHU1,2, ZHENGUO QIAO3, YANG LU4, XIUWEI MI4, HUIHUA CAO5, GENHAI SHEN1,*, SONGBING HE4,*

    Oncology Research, Vol.32, No.2, pp. 353-360, 2024, DOI:10.32604/or.2023.042986

    Abstract Colorectal cancer (CRC) stands among the top prevalent cancers worldwide and holds a prominent position as a major contributor to cancer-related mortality globally. Absent in melanoma 2 (AIM2), a constituent of the interferon-inducible hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats protein family, contributes to both cancer progression and inflammasome activation. Despite this understanding, the precise biological functions and molecular mechanisms governed by AIM2 in CRC remain elusive. Consequently, this study endeavors to assess AIM2’s expression levels, explore its potential antitumor effects, elucidate associated cancer-related processes, and decipher the underlying signaling pathways in CRC. Our findings showed a reduced… More > Graphic Abstract

    Absent in melanoma 2 attenuates proliferation and migration and promotes apoptosis of human colorectal cancer cells by activating P38MAPK signaling pathway

  • Open Access

    ARTICLE

    Application Research on Two-Layer Threat Prediction Model Based on Event Graph

    Shuqin Zhang, Xinyu Su*, Yunfei Han, Tianhui Du, Peiyu Shi

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3993-4023, 2023, DOI:10.32604/cmc.2023.044526

    Abstract Advanced Persistent Threat (APT) is now the most common network assault. However, the existing threat analysis models cannot simultaneously predict the macro-development trend and micro-propagation path of APT attacks. They cannot provide rapid and accurate early warning and decision responses to the present system state because they are inadequate at deducing the risk evolution rules of network threats. To address the above problems, firstly, this paper constructs the multi-source threat element analysis ontology (MTEAO) by integrating multi-source network security knowledge bases. Subsequently, based on MTEAO, we propose a two-layer threat prediction model (TL-TPM) that combines the knowledge graph and the… More >

  • Open Access

    ABSTRACT

    Abstracts from the XLII Annual Meeting of Rosario Society of Biology

    BIOCELL, Vol.47, Suppl.5, pp. 1-23, 2023

    Abstract This article has no abstract. More >

  • Open Access

    ABSTRACT

    Abstracts from the XL Annual Meeting of Sociedad de Biología de Cuyo

    BIOCELL, Vol.47, Suppl.4, pp. 1-83, 2023

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Identification of an immune classifier for predicting the prognosis and therapeutic response in triple-negative breast cancer

    KUAILU LIN1,2, QIANYU GU2, XIXI LAI2,3,*

    BIOCELL, Vol.47, No.12, pp. 2681-2696, 2023, DOI:10.32604/biocell.2023.043298

    Abstract Objectives: Triple-negative breast cancer (TNBC) poses a significant challenge due to the lack of reliable prognostic gene signatures and an understanding of its immune behavior. Methods: We analyzed clinical information and mRNA expression data from 162 TNBC patients in TCGA-BRCA and 320 patients in METABRIC-BRCA. Utilizing weighted gene coexpression network analysis, we pinpointed 34 TNBC immune genes linked to survival. The least absolute shrinkage and selection operator Cox regression method identified key TNBC immune candidates for prognosis prediction. We calculated chemotherapy sensitivity scores using the “pRRophetic” package in R software and assessed immunotherapy response using the Tumor Immune Dysfunction and… More >

  • Open Access

    ARTICLE

    Characterization of Flame Retardancy and Oil-Water Separation Capacity of Superhydrophobic Silylated Melamine Sponges

    Yongchun Liu1,*, Ni Qiao2, Yanli Yang3, Yanchun Li1, Chunxiao He1, Siyang Wang1, Chengcheng Liu1, Ruixia Lei1, Wang Li4, Wenwen Gao4

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.2, pp. 383-400, 2024, DOI:10.32604/fdmp.2023.041928

    Abstract A silylated melamine sponge (SMS) was prepared by two simple steps, namely, immersion and dehydration of a melamine sponge coated with methyltrichlorosilane. The silylated structure of SMS was characterized by FT-IR (Fourier-transform infrared) spectroscopy, SEM (Scanning electron microscopy) and in terms of water contact angles. Its oil-water absorption and separation capacities were measured by FT-IR and UV-visible spectrophotometry. The experimental results have shown that oligomeric silanol covalently bonds by Si−N onto the surface of melamine sponge skeletons. SMS has shown superhydrophobicity with a water contact angle exceeding 150° ± 1°, a better separation efficiency with regard to diesel oil (by 99.31% (wt/wt%)… More >

  • Open Access

    ARTICLE

    Numerical Investigation Thermal Performance of Solar Air Heater Using Different Angle V-Grooved of Corrugated Absorber Plate

    Ayad S. Abedalh*, Sohaib Hassan Mohammed

    Frontiers in Heat and Mass Transfer, Vol.21, pp. 227-243, 2023, DOI:10.32604/fhmt.2023.041777

    Abstract Solar energy, a renewable resource, can be harnessed instead of fossil fuels to generate power and heat. One effective method for converting solar energy into heat is through a solar air heating (SAH) system. The theoretical investigation focused on the thermal performance of various V-groove angles on a corrugated absorber plate. The researchers maintained the exterior dimensions and constraints of the absorber plate while increasing its surface area by using a corrugated absorber surface. For the simulation, three different V-groove angles were employed: 45°, 30°, and 15°. The temperature and air flow rate into the system had been set at… More > Graphic Abstract

    Numerical Investigation Thermal Performance of Solar Air Heater Using Different Angle V-Grooved of Corrugated Absorber Plate

  • Open Access

    ARTICLE

    ENTROPY GENERATION IN BOUNDARY LAYER FLOW OF A MICRO POLAR FLUID OVER A STRETCHING SHEET EMBEDDED IN A HIGHLY ABSORBING MEDIUM

    M. Y. Abdollahzadeh Jamalabadi*

    Frontiers in Heat and Mass Transfer, Vol.6, pp. 1-13, 2015, DOI:10.5098/hmt.6.7

    Abstract An analytical study of entropy generation in steady boundary layer flow, heat and mass transfer characteristic of 2D convective flow of a micro polar fluid over a stretching sheet embedded through a highly absorbing medium is performed. The governing equations are continuity, momentum boundary layer, micro rotation, and energy takes into account of Rosseland approximation for thermal radiation sources are solved analytically. The governing system of partial differential equations is first transformed into a system of non-linear ordinary differential equations using similarity transformation. The transformed equations are non-linear coupled differential equations which are then linearized by quasi-linearization method and solved… More >

  • Open Access

    ARTICLE

    THERMAL DIFFUSION AND ROTATIONAL EFFECTS ON MAGNETO HYDRODYNAMIC MIXED CONVECTION FLOW OF HEAT ABSORBING/GENERATING VISCO- ELASTIC FLUID THROUGH A POROUS CHANNEL

    L. Ramamohan Reddya , M. C. Rajub,*, G.S.S. Rajuc, N. A. Reddyb

    Frontiers in Heat and Mass Transfer, Vol.7, pp. 1-12, 2016, DOI:10.5098/hmt.7.20

    Abstract This investigation presents an analytical study on magnetohydrodynamic (MHD), convective flow of a viscoelastic, incompressible, radiative, chemically reactive, electrically conducting and rotating fluid through a porous medium filled in a vertical channel in the presence of thermal diffusion. A magnetic field of uniform strength is applied along the axis of rotation. The fluid is assumed to act on with a periodic time variation of the pressure gradient in upward direction vertically. One of the plates is maintained at non-uniform temperature and the temperature difference of the walls of the channel is assumed high enough that induces heat transfer due to… More >

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