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  • Open Access

    ARTICLE

    The Impact of Exercise Commitment on Flourishing via Psychological Capital (PsyCap): A Second-Order PLS-SEM Approach

    Jinwoong Choi1, Young-lae Choi2, Kyuhyun Choi2,*

    International Journal of Mental Health Promotion, Vol.27, No.10, pp. 1515-1532, 2025, DOI:10.32604/ijmhp.2025.068306 - 31 October 2025

    Abstract Objectives: For the younger generation (i.e., Millennials and Generation Z), running is not only about physical health, but also about building psychological resources and multidimensional well-being, reflecting their unique culture and lifestyle. This study aims to investigate the structural relationships among exercise commitment, psychological capital (PsyCap), and flourishing in younger adults in South Korea by integrating Social Cognitive Theory (SCT) and Broaden-and-Build Theory (BBT) using a second-order partial least squares structural equation modeling (PLS-SEM). Methods: A total of 166 participants were recruited through convenience sampling via online survey. They were young South Korean adults (born… More >

  • Open Access

    ARTICLE

    GC-MS Analysis and Tyrosinase Inhibitory Potential of Pimenta dioica Flower Essential Oil

    Heba A. S. El-Nashar1,*, Ahmed T. Negmeldin2,3,*, Aziza El Baz4, Marizé Cuyler5, Brandon Alston5, Namrita Lall5,6,7, Naglaa S. Ashmawy1,8,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3269-3281, 2025, DOI:10.32604/phyton.2025.067998 - 29 October 2025

    Abstract Pimenta dioica is a tropical Caribbean tree belonging to the family Myrtaceae, widely used in various human activities, including perfume production, food flavoring, natural pesticides, and medicine. This study aimed to explore the chemical composition of Pimenta dioica flower essential oil obtained via hydrodistillation using GC-MS analysis. Additionally, the oil’s tyrosinase inhibitory activity was investigated. The effectiveness of the oil’s major constituents in binding to tyrosinase was also evaluated through molecular docking simulations. GC-MS analysis identified fifteen compounds, with eugenol (70.59%) as the major component, followed by β-myrcene (10.54%), limonene (8.55%), β-ocimene (4.92%), α-phellandrene (1.39%), and linalool… More >

  • Open Access

    ARTICLE

    Leveraging Federated Learning for Efficient Privacy-Enhancing Violent Activity Recognition from Videos

    Moshiur Rahman Tonmoy1, Md. Mithun Hossain1, Mejdl Safran2,*, Sultan Alfarhood2, Dunren Che3, M. F. Mridha4

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5747-5763, 2025, DOI:10.32604/cmc.2025.067589 - 23 October 2025

    Abstract Automated recognition of violent activities from videos is vital for public safety, but often raises significant privacy concerns due to the sensitive nature of the footage. Moreover, resource constraints often hinder the deployment of deep learning-based complex video classification models on edge devices. With this motivation, this study aims to investigate an effective violent activity classifier while minimizing computational complexity, attaining competitive performance, and mitigating user data privacy concerns. We present a lightweight deep learning architecture with fewer parameters for efficient violent activity recognition. We utilize a two-stream formation of 3D depthwise separable convolution coupled More >

  • Open Access

    ARTICLE

    Facile Preparation of Robust Peach Gum Polysaccharide with Remarkably Enhanced Antibacterial and Antioxidant Performance

    Mengting Huang, Meiting Lu, Li Yang, Jiwen Long, Li Zhou*

    Journal of Renewable Materials, Vol.13, No.10, pp. 2077-2090, 2025, DOI:10.32604/jrm.2025.02025-0122 - 22 October 2025

    Abstract Peach gum polysaccharide (PGP), a readily available natural polysaccharide, boasts substantial potential across diverse applications, yet its practical utility is severely limited by its vulnerability to bacterial growth and limited antioxidant activity. Herein, we introduced a simple and effective method to enhance the antibacterial and antioxidant properties of PGP by conjugating it with salicylic acid (SA). Cytotoxicity evaluation results confirmed that the resulting PGP-SA retains the excellent biocompatibility of PGP. Notably, PGP-SA demonstrates outstanding antibacterial activity against both Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria, outperforming non-modified PGP. Its antibacterial mechanism is hypothesized to stem from… More > Graphic Abstract

    Facile Preparation of Robust Peach Gum Polysaccharide with Remarkably Enhanced Antibacterial and Antioxidant Performance

  • Open Access

    ARTICLE

    Alisol A Exerts Anti-Proliferative Activity against Human Oral Cancer Cells through Triggering JNK/p38 MAPK-Mediated Apoptotic Cascade

    Yi-Tzu Chen1,2,3,#, Shao-Hsuan Kao4,5,#, Chun-Yi Chuang6,7, Chun-Wen Su4,5, Wei-En Yang4,5, Chih-Hsin Tang8,9,10, Shun-Fa Yang4,5,*, Chiao-Wen Lin2,3,*

    Oncology Research, Vol.33, No.11, pp. 3387-3404, 2025, DOI:10.32604/or.2025.069877 - 22 October 2025

    Abstract Background: Alisol A is a natural compound isolated from Alismatis Rhizoma, known for its diverse pharmacological activities, including anticancer and neuroprotective effects. This study aimed to explore the anticancer effects of Alisol A on oral cancer cells and elucidate its underlying mechanisms. Methods: Cell viability was measured by MTT assay, cell cycle by flow cytometry, and apoptosis by Annexin V/PI staining and caspase activation. Regulation of signaling pathways was analyzed using an apoptosis-related protein array, immunoblotting, and specific kinase inhibitors. Results: Alisol A reduced the viability of oral cancer cell lines, induced sub-G1 phase accumulation, and augmented… More >

  • Open Access

    ARTICLE

    Relationship between Resilience and Physical Activity in Adolescents: The Role of Family Functioning

    Dingmeng Mao1, Guannan Bai2, Lin Yang3,4,5, Jane Jie Yu1,*

    International Journal of Mental Health Promotion, Vol.27, No.9, pp. 1221-1235, 2025, DOI:10.32604/ijmhp.2025.069810 - 30 September 2025

    Abstract Background: Physical inactivity among adolescents has become a global public health challenge, with over 80% failing to meet the recommendations of the WHO for activity levels. Existing research predominantly examines how physical activity (PA) enhances resilience, while the predictive role of resilience in PA, particularly its interaction with family factors, has received limited attention. This study aimed to examine the associations between resilience and PA among adolescents, focusing on family functioning and gender differences. Methods: In this cross-sectional study, a total of 909 Chinese adolescents (463 males and 446 females, aged 13.3 ± 0.5 years)… More >

  • Open Access

    ARTICLE

    Sustainable Removal of Cu2+ and Pb2+ Ions via Adsorption Using Polyvinyl Alcohol/Neem Leaf Extract/Chitosan (From Shrimp Shells) Composite Films

    Deepti Rekha Sahoo, Trinath Biswal*

    Journal of Polymer Materials, Vol.42, No.3, pp. 811-835, 2025, DOI:10.32604/jpm.2025.067022 - 30 September 2025

    Abstract The purpose of this research work is to determine the removal efficiency of Cu2+ and Pb2+ ions using polyvinyl alcohol/neem leaf extract/chitosan (PVA/NLE/CS) composite films as adsorbent materials from an aqueous medium, with respect to pH, contact time, and adsorbent dosage. The synthesized composite material was characterized using Fourier Transform Infrared (FTIR) spectroscopy, thermogravimetric analysis-Derivative Thermogravimetry (TGA-DTG), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy-Energy Dispersive X-ray Spectroscopy (SEM-EDX). The antibacterial activity and swelling response of the material were studied using suitable methodologies. The FTIR study confirmed the interactions among PVA, chitosan, and… More >

  • Open Access

    ARTICLE

    Active Learning-Enhanced Deep Ensemble Framework for Human Activity Recognition Using Spatio-Textural Features

    Lakshmi Alekhya Jandhyam1,*, Ragupathy Rengaswamy1, Narayana Satyala2

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.3, pp. 3679-3714, 2025, DOI:10.32604/cmes.2025.068941 - 30 September 2025

    Abstract Human Activity Recognition (HAR) has become increasingly critical in civic surveillance, medical care monitoring, and institutional protection. Current deep learning-based approaches often suffer from excessive computational complexity, limited generalizability under varying conditions, and compromised real-time performance. To counter these, this paper introduces an Active Learning-aided Heuristic Deep Spatio-Textural Ensemble Learning (ALH-DSEL) framework. The model initially identifies keyframes from the surveillance videos with a Multi-Constraint Active Learning (MCAL) approach, with features extracted from DenseNet121. The frames are then segmented employing an optimized Fuzzy C-Means clustering algorithm with Firefly to identify areas of interest. A deep ensemble More >

  • Open Access

    ARTICLE

    Acalypha gaumeri: Antifungal Activity of Three Populations under Edaphic and Seasonal Variations and Ex-Situ Propagation

    Arely A. Vargas-Díaz1, Daisy Pérez-Brito2, Beatriz Hernández-Carlos3, Jairo Cristóbal-Alejo4,*, Silvia Andrade-Canto2, Marcela Gamboa-Angulo2,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.9, pp. 2839-2853, 2025, DOI:10.32604/phyton.2025.066682 - 30 September 2025

    Abstract In the search for new alternatives to control tropical fungal pathogens, the ethanol extracts (EEs) from Acalypha gaumeri (Euphorbiaceae) roots showed antifungal properties against several tropical fungal phytopathogens. A. gaumeri is classified as endemic to the Yucatan Peninsula, Mexico, an area with distinct rainy, drought and northern seasons. The present study evaluated the antifungal activity of three wild populations of A. gaumeri collected quarterly in different seasons during one year against Alternaria chrysanthemi, Colletotrichum gloeosporioides, and Pseudocercospora fijiensis and explored their ex-situ propagation. The highest activity was shown by the EE from the Tinum wild population during the rainy season against A. chrysanthemi,… More >

  • Open Access

    REVIEW

    Multi-Target Biological Activities of Podophyllotoxin-Derived Natural Products

    Yuhan Xie1, Shaden A. M. Khalifa2, Hesham R. El-Seedi3, Paolo Coghi1,4,*

    Oncology Research, Vol.33, No.10, pp. 2673-2697, 2025, DOI:10.32604/or.2025.067666 - 26 September 2025

    Abstract Podophyllotoxin is a well-studied natural product. Because of its unique structure and ability to inhibit cancer cells, it has been changed in different ways to find out its pharmacological properties. This paper discusses the common chemical modifications of podophyllotoxin molecules, including the C-4 and E-4 site replacements. Furthermore, its common inhibitory effects on cancer cells and antiparasitic activities, among others, are outlined by the connection between conformational changes and pharmacological activities. Importantly, Podophyllotoxin can effectively overcome the phenomenon of multidrug resistance through a dual-targeting mechanism, including inhibition of microtubule protein synthesis and topoisomerase II activity, More > Graphic Abstract

    Multi-Target Biological Activities of Podophyllotoxin-Derived Natural Products

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