Yan Wu1, Xuerui An1, Haofan Lv1, Zhiqiang Zhao1, Wei Liu1,2,*, Chunpeng Wan1,3,*
Phyton-International Journal of Experimental Botany, Vol.94, No.1, pp. 199-207, 2025, DOI:10.32604/phyton.2025.059581
- 24 January 2025
Abstract
A novel pair of oleanane nor-triterpenes, with compound 1 featuring a unique 18α-H structure, was isolated from mastic, and this compound represents a noteworthy new entity not previously reported in the literature. The absolute configurations of their structures were further determined using a combination of different analytical methods such as NMR, high-resolution mass spectrometry (HR-MS), ultraviolet (UV), infrared (IR) and single-crystal X-ray diffraction (SXRD). The compound actively mitigated inflammations by efficiently quenching nitric oxide (NO) synthesis within an ex vivo system using lipopolysaccharide activated murine macrophage RAW264.7 cells. Moreover, compound 1 exhibit a better IC50 concentration of More >