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  • Open Access

    REVIEW

    Translational aspects of the modern genetics in head and neck cancers

    FRANCESCO PADUANO1,2,*, EMANUELA ALTOMARE2,3, BENEDETTA MARRELLI1, VINCENZO DATTILO4, HAIZAL MOHD HUSSAINI5, PAUL ROY COOPER5, MARCO TATULLO6

    BIOCELL, Vol.46, No.8, pp. 1827-1835, 2022, DOI:10.32604/biocell.2022.020462

    Abstract Oral Cancer (OC) is one of the most recurrent cancers in the head and neck squamous cancer (SCCHN) category. Recently, the genome-wide association studies (GWAS) have gained growing interest in the scientific community. GWAS have identified several pathways involved in the interactions among general risk factors and genomic variants affecting SCCHN. This systematic overview aims to critically evaluate the latest data reported within the scientific literature. The aim was to investigate the impact of genetic aspects on SCCHN onset and prognosis, involving other clinical and systemic co-factors. PubMed, Google Scholar, and Cancer Genetics Web databases have been systematically investigated for… More >

  • Open Access

    ARTICLE

    Numerical Aspects of Isogeometric Boundary Element Methods: (Nearly) Singular Quadrature, Trimmed NURBS and Surface Crack Modeling

    Xuan Peng1,*, Haojie Lian2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.1, pp. 513-542, 2022, DOI:10.32604/cmes.2022.017410

    Abstract This work presents some numerical aspects of isogeometric boundary element methods (IGABEM). The behavior of hyper-singular and nearly-singular integration is first explored on the distorted NURBS surface. Several numerical treatments are proposed to enhance the quadrature in the framework of isogeometric analysis. Then a numerical implementation of IGABEM on the trimmed NURBS is detailed. Based on this idea, the surface crack problem is modeled incorporation with the phantom element method. The proposed method allows the crack to intersect with the boundary of the body while preserving the original parametrization of the NURBS-based CAD geometry. More >

  • Open Access

    ARTICLE

    Multi-Level Knowledge Engineering Approach for Mapping Implicit Aspects to Explicit Aspects

    Jibran Mir1, Azhar Mahmood2,*, Shaheen Khatoon3

    CMC-Computers, Materials & Continua, Vol.70, No.2, pp. 3491-3509, 2022, DOI:10.32604/cmc.2022.019952

    Abstract Aspect's extraction is a critical task in aspect-based sentiment analysis, including explicit and implicit aspects identification. While extensive research has identified explicit aspects, little effort has been put forward on implicit aspects extraction due to the complexity of the problem. Moreover, existing research on implicit aspect identification is widely carried out on product reviews targeting specific aspects while neglecting sentences’ dependency problems. Therefore, in this paper, a multi-level knowledge engineering approach for identifying implicit movie aspects is proposed. The proposed method first identifies explicit aspects using a variant of BiLSTM and CRF (Bidirectional Long Short Memory-Conditional Random Field), which serve… More >

  • Open Access

    ARTICLE

    Security and Privacy Aspects of Cloud Computing: A Smart Campus Case Study

    Sajid Habib Gill1, Mirza Abdur Razzaq1, Muneer Ahmad2, Fahad M. Almansour3, Ikram Ul Haq4, NZ Jhanjhi5,*, Malik Zaib Alam6, Mehedi Masud7

    Intelligent Automation & Soft Computing, Vol.31, No.1, pp. 117-128, 2022, DOI:10.32604/iasc.2022.016597

    Abstract The trend of cloud computing is accelerating along with emerging technologies such as utility computing, grid computing, and distributed computing. Cloud computing is showing remarkable potential to provide flexible, cost-effective, and powerful resources across the internet, and is a driving force in today’s most prominent computing technologies. The cloud offers the means to remotely access and store data while virtual machines access data over a network resource. Furthermore, cloud computing plays a leading role in the fourth industrial revolution. Everyone uses the cloud daily life when accessing Dropbox, various Google services, and Microsoft Office 365. While there are many advantages… More >

  • Open Access

    ARTICLE

    CFD-Based Simulation and Analysis of Hydrothermal Aspects in Solar Channel Heat Exchangers with Various Designed Vortex Generators

    Mohamed Salmi1,2, Younes Menni3, Ali J. Chamkha4,5,*, Houari Ameur6, Rachid Maouedj7, Ahmed Youcef7

    CMES-Computer Modeling in Engineering & Sciences, Vol.126, No.1, pp. 147-173, 2021, DOI:10.32604/cmes.2021.012839

    Abstract The hydrothermal behavior of air inside a solar channel heat exchanger equipped with various shaped ribs is analyzed numerically. The bottom wall of the exchanger is kept adiabatic, while a constant value of the temperature is set at the upper wall. The duct is equipped with a flat rectangular fin on the upper wall and an upstream V-shaped baffle on the lower wall. Furthermore, five hot wall-attached rib shapes are considered: trapezoidal, square, triangular pointing upstream (type I), triangular pointing downstream (type II), and equilateral-triangular (type III) cross sections. Effects of the flow rates are also inspected for various Reynolds… More >

  • Open Access

    ARTICLE

    Sawdust Short Fiber Reinforced Epoxidized Natural Rubber: Insight on Its Mechanical, Physical, and Thermal Aspects

    O. S. Dahham1, N. Z. Noriman1,2,*, H. Jaya1, R. Hamzah1, M. U. Umar2,3, I. Johari4

    Journal of Renewable Materials, Vol.8, No.12, pp. 1633-1645, 2020, DOI:10.32604/jrm.2020.011377

    Abstract In this work, Epoxidized natural rubber/sawdust short fiber (ENR-50/ SD) composites at different fiber content (5, 10, 15 and 20 phr) and size (fine size at 60–100 μm and coarse size at 10–20 mm) were prepared using two-roll mill and electrical-hydraulic hot press machine respectively. Curing characteristics, water uptake, tensile, morphological, physical, and thermal properties of the composites were investigated. Results indicated that the scorch time and cure time became shorter whereas torque improved as SD content increase. Though the decline of tensile strength and elongation at break values, modulus, hardness and crosslinking density have shown enhancements with the increasing… More >

  • Open Access

    ARTICLE

    Effects of Different Geographical Aspects and Ontogenetic Variability on Total Hypericin Content of Hypericum triquetrifolium Turra. and Hypericum scabrum L.

    Emine Aslan, Dogan Arslan*

    Phyton-International Journal of Experimental Botany, Vol.89, No.4, pp. 1091-1099, 2020, DOI:10.32604/phyton.2020.010835

    Abstract The present study was conducted to determine the total hypericin contents of Hypericum triquetrifolium Turra. and Hypericum scabrum L. species which are naturally distributed in the flora of Siirt province, Turkey. Hypericin contents of Hypericum species grown in different geographical aspects (North, South, East, and West), and it was measured at different harvest times (full blooming and post blooming period). In the current study, it has been determined that total hypericin content varies considerably according to aspects, plant developmental stages (ontogenetic variance), and species. According to species x aspect interaction, the highest total hypericin content was recorded from the west… More >

  • Open Access

    ARTICLE

    Aspects of Fretting Fatigue Finite Element Modelling

    Kyvia Pereira1, Libardo V. Vanegas-Useche2, Magd Abdel Wahab3, 4, *

    CMC-Computers, Materials & Continua, Vol.64, No.1, pp. 97-144, 2020, DOI:10.32604/cmc.2020.09862

    Abstract Fretting fatigue is a type of failure that may affect various mechanical components, such as bolted or dovetail joints, press-fitted shafts, couplings, and ropes. Due to its importance, many researchers have carried out experimental tests and analytical and numerical modelling, so that the phenomena that govern the failure process can be understood or appropriately modelled. Consequently, the performance of systems subjected to fretting fatigue can be predicted and improved. This paper discusses different aspects related to the finite element modelling of fretting fatigue. It presents common experimental configurations and the analytical solutions for cylindrical contact. Then, it discusses aspects of… More >

  • Open Access

    ARTICLE

    Clinical, echocardiographic, and therapeutic aspects of congenital heart diseases of children at Douala General Hospital: A cross-sectional study in sub-Saharan Africa

    Felicit e Kamdem1,2, Danielle Kedy Koum2,3, Ba Hamadou1,4, Melanie Yemdji1, Henry Luma1,4, Marie Solange Doualla1,4, Diomède Noukeu5, Esther Barla5, Christophe Akazong5, Anastase Dzudie1,4, Henry Ngote1, Yves Monkam1, Sidiki Mouliom1, Samuel Kingue4,6

    Congenital Heart Disease, Vol.13, No.1, pp. 113-117, 2018, DOI:10.1111/chd.12529

    Abstract Introduction: Cardiovascular diseases in pediatric pathologies have emerged in the recent years in sub-Saharan Africa (SSA), with congenital heart diseases (CHDs) being the most frequent. Unfortunately, their diagnosis is usually delayed, thereby increasing childhood morbidity and mortality.
    Objectives: Describe the clinical, echocardiographic, and therapeutic aspects of CHDs of children at Douala General Hospital.
    Methods: We carried out a cross-sectional descriptive study over a 10-year period, from January 2006 to December 2015. Files and reports of cardiac ultrasounds of patients aged ≤ 15 years were reviewed.
    Results: We reviewed the medical records of 1616 children, of which 370 (22.9%) had CHD.… More >

  • Open Access

    ABSTRACT

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