Xue Song^1,2, Cun Liu², Jingying Wang^1,*, Xinglian Yang¹, Mingrui Li¹

Molecular & Cellular Biomechanics, Vol.19, No.4, pp. 209-219, 2022, DOI:10.32604/mcb.2022.026082

Abstract The umbilical cord is a vital structure between the fetus and placenta for the growth and well-being of the fetus. Although the umbilical cord may be the only organ that dies at the beginning of life, it is one of the most important parts of the feta-placental unit and plays a role in determining how life begins. In general, the prenatal examination of the umbilical cord is limited to the observation of the number of vessels and the evaluation of umbilical artery blood flow parameters. Pathologists have done more research on the morphological characteristics of the umbilical cord and linked… More >

Anupam Krishnan¹, Anjana P. Anantharaman^2,*

Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 77-88, 2022, DOI:10.32604/mcb.2022.018369

Abstract Computational Fluid Dynamics has become relevant in the study of hemodynamics, where clinical results are challenging to obtain. This paper discusses a 2-Dimensional transient blood flow analysis through an arterial bifurcation for patients infected with the Coronavirus. The geometry considered is an arterial bifurcation with main stem diameter 3 mm and two outlets. The left outlet (smaller) has a diameter of 1.5 mm and the right outlet (larger), 2 mm. The length of the main stem, left branch and right branch are fixed at 35 mm, 20 mm and 25 mm respectively. Viscosity change that occurs in the blood leads… More >

Sibao Wang, Silin Pan^*, Gang Luo, Zhixian Ji, Na Liu

Congenital Heart Disease, Vol.17, No.1, pp. 45-60, 2022, DOI:10.32604/CHD.2022.016332

Abstract The aim of this study was to perform a systematic review and meta-analysis to evaluate the safety and efficacy of ductus arteriosus stent (DAS) compared with surgical systemic-pulmonary artery shunt (SPS) in patients with ductal-dependent pulmonary blood flow. A literature search was conducted in PubMed, Embase, and the Cochrane Library databases from their inception to December 2020. Two reviewers independently screened the articles, evaluated the quality of the articles, and collected the data. Meta-analyses were conducted using fixed and random effects models. We used the I-square (I² ) test to examine heterogeneity and the funnel plot Egger’s test was used… More >

Yajuan Zhang, Jun Yan^*, Qiang Wang, Shoujun Li, Jing Sun, Shuo Dong, Jiachen Li

Congenital Heart Disease, Vol.16, No.4, pp. 383-392, 2021, DOI:10.32604/CHD.2021.015479

Abstract Background: The long-term outcomes of patients treated with a Kawashima procedure and keeping the antegrade pulmonary blood flow (AnPBF) in single-ventricle (SV) and interrupted inferior vena cava (IVC) heart disease is still uncertain as yet. Methods: We investigated 18 patients who underwent the Kawashima procedure with SV physiology and an interrupted IVC between January 2009 and June 2018, perioperative, operative and postoperative characteristics were recorded. Results: A total of 18 patients underwent the Kawashima procedure at a median age of 2.7 years (range 0.5–24.7 years), of which 12 (66.7%) were male and 6 (33.3%) were female. The mean saturation was… More >

Anees Imitaz¹, Aamina Aamina¹, Farhad Ali^2,3,*, Ilyas Khan⁴, Kottakkaran Sooppy Nisar⁵

CMC-Computers, Materials & Continua, Vol.66, No.3, pp. 2253-2264, 2021, DOI:10.32604/cmc.2021.012470

Abstract The present study is focused on the unsteady two-phase flow of blood in a cylindrical region. Blood is taken as a counter-example of Brinkman type fluid containing magnetic (dust) particles. The oscillating pressure gradient has been considered because for blood flow it is necessary to investigate in the form of a diastolic and systolic pressure. The transverse magnetic field has been applied externally to the cylindrical tube to study its impact on both fluids as well as particles. The system of derived governing equations based on Navier Stoke’s, Maxwell and heat equations has been generalized using the well-known Caputo–Fabrizio (C–F)… More >

Anber Saleem^1,2, Salman Akhtar³, Sohail Nadeem^3,*, Alibek Issakhov⁴, Mehdi Ghalambaz^5,6

CMES-Computer Modeling in Engineering & Sciences, Vol.125, No.2, pp. 565-577, 2020, DOI:10.32604/cmes.2020.011883

Abstract The blood flow through a catheterized artery having a mild stenosis at the wall together with a blood clot at the centre is studied in the current investigation. Stenosis can occur in vessels carrying blood to brain (i.e., Carotid arteries), Renal arteries that supply blood to kidneys etc. The flow is refined in such vessels by application of catheter. We have used a Newtonian viscous fluid model and also distinct shapes of stenosis, (i.e., symmetric and non-symmetric shapes) are considered for this study. The entropy generation together with viscous dissipation is also taken into account for a complete description of… More >

Anees Imtiaz¹, Oi-Mean Foong², Aamina Aamina¹, Nabeel Khan¹, Farhad Ali^{3, 4, *}, Ilyas Khan⁵

CMC-Computers, Materials & Continua, Vol.65, No.1, pp. 171-192, 2020, DOI:10.32604/cmc.2020.011397

Abstract Gold metallic nanoparticles are generally used within a lab as a tracer, to uncover on the presence of specific proteins or DNA in a sample, as well as for the recognition of various antibiotics. They are bio companionable and have properties to carry thermal energy to tumor cells by utilizing different clinical approaches. As the cancer cells are very smaller so for the infiltration, the properly sized nanoparticles have been injected in the blood. For this reason, gold nanoparticles are very effective. Keeping in mind the above applications, in the present work a generalized model of blood flow containing gold… More >

Lijian Xu¹, Tianyang Yang², Lekang Yin³, Ye Kong², Yuri Vassilevski^4,5, Fuyou Liang^1,5,6,*

CMES-Computer Modeling in Engineering & Sciences, Vol.124, No.2, pp. 509-526, 2020, DOI:10.32604/cmes.2020.010719

Abstract Computational modeling methods have been increasingly employed to quantify aortic hemodynamic parameters that are challenging to in vivo measurements but important for the diagnosis/treatment of aortic disease. Although the presence of turbulence-like behaviors of blood flow in normal or diseased aorta has long been confirmed, the majority of existing computational model studies adopted the laminar flow assumption (LFA) in the treatment of sub-grid flow variables. So far, it remains unclear whether LFA would significantly compromise the reliability of hemodynamic simulation. In the present study, we addressed the issue in the context of a specific aortopathy, namely aortic dilation, which is… More >

Rachel Wong¹, Mohammed Al‐Omary², David Baker², Neil Spratt^1,2, Andrew Boyle^1,2, Natasha Baker Cert¹, Peter Howe¹, Nicholas Collins²

Congenital Heart Disease, Vol.14, No.4, pp. 638-644, 2019, DOI:10.1111/chd.12763

Abstract Objectives: Improvements in the management of complex congenital heart disease, including those with single ventricle physiology, have resulted in increased survival. As this population ages, the recognition of cognitive impairment is increasingly im‐ portant. At present, little is known about the potential mechanisms of cognitive dys‐ function. In this cross‐sectional study, we aimed to characterize the nature of abnormalities in cerebral blood flow and the relationship to cognitive deficits in adults with single ventricular physiology.
Patients: Ten adults with single ventricular physiology (age 18‐40 years) and 12 age‐ and gender‐matched controls underwent transcranial Doppler ultrasound and ac‐ companying cognitive assessment.
… More >

Nurdan Ozturk Tasar¹, Pelin Kosger², Nevzat Uzuner³, Birsen Ucar²

Congenital Heart Disease, Vol.13, No.6, pp. 1038-1044, 2018, DOI:10.1111/chd.12678

Abstract Objective: We aimed to investigate the effect of ventricular septal defect (VSD) and heart failure on cerebral blood flow (CBF) in children, whether heart failure treatment improves CBF, and if there is any relationship between CBF and serum N‐ terminal pro‐brain natriuretic peptide (NT‐proBNP) level.
Method: Forty children with VSD (13 with heart failure) aged between 1 and 36 months were studied. The control group comprised 25 healthy children in the same age group. Maximum, minimum, and mean blood flow velocities and pulsatility indices of the right and left middle cerebral arteries were assessed using transcranial Doppler ultrasonography. Measurements of… More >