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  • Open Access

    ARTICLE

    Multifrequency Microwave Imaging for Brain Stroke Detection

    Lulu Wang1,*

    Molecular & Cellular Biomechanics, Vol.17, No.1, pp. 33-40, 2020, DOI:10.32604/mcb.2019.07165

    Abstract CT and MRI are often used in the diagnosis and monitoring of stroke. However, they are expensive, time-consuming, produce ionizing radiation (CT), and not suitable for continuous monitoring stroke. Microwave imaging (MI) has been extensively investigated for identifying several types of human organs, including breast, brain, lung, liver, and gastric. The authors recently developed a holographic microwave imaging (HMI) algorithm for biological object detection. However, this method has difficulty in providing accurate information on embedded small inclusions. This paper describes the feasibility of the use of a multifrequency HMI algorithm for brain stroke detection. A numerical system, including HMI data… More >

  • Open Access

    ABSTRACT

    Supplement. 10 Symposium: BIOLOGY AND CULTURE OF SILVERSIDES (PEJERREYES) Characterization of the Brain-pituitary axis in pejerrey Odontesthes bonariensis

    G.M. SOMOZA, L.A. MIRANDA, L.G. GUILGUR, P.H. STROBL-MAZZULLA

    BIOCELL, Vol.30, Suppl.S, pp. 89-95, 2006

    Abstract This article has no abstract. More >

  • Open Access

    REVIEW

    Review: Studies on the reproductive and developmental biology of Cichlasoma dimerus (Percifomes, Cichlidae)

    MATÍAS PANDOLFI*, MAXIMILIANO M. CÁNEPA, FERNANDO J. MEIJIDE, FELIPE ALONSO, GRACIELA REY VÁZQUEZ, M. CRISTINA MAGGESE, PAULA G. VISSIO

    BIOCELL, Vol.33, No.1, pp. 1-18, 2009, DOI:10.32604/biocell.2009.33.001

    Abstract Many characteristics of the South American teleost fish Cichlasoma dimerus (body size, easy breeding, undemanding maintenance) make it amenable to laboratory studies. In the last years, many of the fundamental aspects of its reproductive and developmental biology have been addressed in our laboratory. Rather recently, the immunohistochemical localization of pituitary hormones involved in reproduction and in background color adaptation has been described in both adult and developing individuals, and the role of FSH in ovarian differentiation has been established. These findings have been correlated with mapping of some of their brain-derived controlling hormones. The latter include brain-derived gonadotropins which were… More >

  • Open Access

    ARTICLE

    CAS role in the brain apoptosis of Bufo arenarum induced by cypermethrin

    M. F. IZAGUIRRE, M. N. VERGARA, V. H. CASCO.

    BIOCELL, Vol.30, No.2, pp. 309-320, 2006, DOI:10.32604/biocell.2006.30.309

    Abstract CAS might have a key role in the apoptosis induced by toxins, acting as anti-apoptotic factor, stimulating the cellular proliferation and the cell contact stabilization. To start to elucidate their role in the brain apoptosis of Bufo arenarum induced by cypermethrin (CY), the expression patterns of CAS and several cell adhesion molecules (CAMs) were established.
    Bufo arenarum tadpoles of the control and acute bioassay survival at different doses (39, 156, 625 and 2,500 μg CY/L) and times (24, 48, 72 and 96 h) of CY treatment were fixed in Carnoy, embedded in paraffin and sectioned. CAS and CAMs expression… More >

  • Open Access

    ABSTRACT

    A New Mass Effect Research Rat Model to Explore the Occuping Effect on Secondary Brain Injuries after ICH

    Yuhua Gong1, Shilei Hao1,*, Bochu Wang1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 143-143, 2019, DOI:10.32604/mcb.2019.07095

    Abstract The mechanical response of brain tissue closely relates to cerebral blood flow and brain diseases. During intracerebral haemorrhage (ICH), a mass effect occurs during the initial bleeding. As the hematoma increases, the haematoma mass effect continues to squeeze the brain tissue mechanically, which can even lead to the formation of fatal cerebral hernia. However, fewer studies have focused on the brain damage mechanisms and treatment approaches associated with mass effects compared to the secondary brain injuries after ICH, which may be a result of the absence of acceptable animal models mimicking a mass effect. Thus, a thermo-sensitive poly (N-isopropylacrylamide) (PNIPAM)… More >

  • Open Access

    ABSTRACT

    Multifrequency Microwave Imaging for Brain Stroke Detection

    Lulu Wang1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 125-125, 2019, DOI:10.32604/mcb.2019.07101

    Abstract Early diagnosis of stroke with timely treatment could reduce adult permanent disability significantly [1]. Conventional medical imaging tools such as X-ray, ultrasound, computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) have been widely used for diagnosis of brain disease. However, each of these methods has some limitations. X-ray imaging produces harmful radiation to the human body and challenging to identify early-stage abnormal tissue due to the relatively small dielectric proprieties contrast between the healthy tissue and abnormal tissue at X-ray frequencies [2]. PET provides useful information about soft tissues, but it is expensive and produces poor… More >

  • Open Access

    ABSTRACT

    Magnetic Resonance Image-Based Modeling for Neurosurgical Interventions

    Yongqiang Li1,#, Changxin Lai1,#, Chengchen Zhang2, Alexa Singer1, Suhao Qiu1, Boming Sun2, Michael S. Sacks3, Yuan Feng1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 111-111, 2019, DOI:10.32604/mcb.2019.07098

    Abstract Surgeries such as implantation of deep brain stimulation devices require accurate placement of devices within the brain. Because placement affects performance, image guidance and robotic assistance techniques have been widely adopted. These methods require accurate prediction of brain deformation during and following implantation. In this study, a magnetic resonance (MR) image-based finite element (FE) model was proposed by using a coupled Eulerian-Lagrangian method. Anatomical accuracy was achieved by mapping image voxels directly to the volumetric mesh space. The potential utility was demonstrated by evaluating the effect of different surgical approaches on the deformation of the corpus callosum (CC) region. The… More >

  • Open Access

    ABSTRACT

    Immune Cells Migrating through the Brain Endothelia Junctions Served as Shuttles for Nanoparticles Delivery to Glioblastoma

    Gloria B. Kim1,†, Qiong Wei2,†, Virginia Aragon-Sanabria1, Sulin Zhang2, Jian Yang1, Cheng Dong1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 15-15, 2019, DOI:10.32604/mcb.2019.07137

    Abstract Most cells survive and grow by attaching and spreading on a substrate. They generate internal tension that contracts the cell body and thus exert tractions on the underlying substrate through focal adhesions. Traction force also plays a critical role in many biological processes, such as inflammation, metastasis, and angiogenesis. Thus, measuring the cell traction force provides valuable information on understanding the underlying mechanism of these biological processes. Here, a traction force microscopy (TFM) method using super thin hydrogels composed of immobilized fluorescent beads was utilized to quantify the mechanical forces generated during the transmigration of Jurkat cells (a human T… More >

  • Open Access

    ABSTRACT

    Protecting the Brain from Calcification in Ischemic Stroke

    Shu Q. Liu1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 5-7, 2019, DOI:10.32604/mcb.2019.06960

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Changes in the redox status of the brain in an experimental glaucoma model

    Claudia G. REIDES1,2, Romina M. LASAGNI VITAR1,2, Agustina PEVERINI1, Natasha S. JANEZIC1, Ailen G. HVOZDA ARANA1, Sandra M. FERREIRA1,2, Susana F. LLESUY1,2*

    BIOCELL, Vol.40, No.1, pp. 51-54, 2016, DOI:10.32604/biocell.2016.40.051

    Abstract The purpose of this study was to evaluate the redox status changes of primary visual targets in the rat brain of a high pressure-induced glaucoma model. The animal model consisted of inducing ocular hypertension by cauterizing two episcleral veins on the left eye. The markers of oxidative damage and the oxidative balance evaluated in the brain seven days postoperative were: nitrites concentration, levels of non-enzymatic antioxidants and antioxidant enzymes activity.
    The increase in the nitrite content, which could be the result of the enhancement in the production of nitrogen species, and in the activity of NADPH oxidase in the glaucoma… More >

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