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  • Open Access

    ARTICLE

    Prediction Model of Wax Deposition Rate in Waxy Crude Oil Pipelines by Elman Neural Network Based on Improved Reptile Search Algorithm

    Zhuo Chen1,*, Ningning Wang2, Wenbo Jin3, Dui Li1

    Energy Engineering, Vol.121, No.4, pp. 1007-1026, 2024, DOI:10.32604/ee.2023.045270

    Abstract A hard problem that hinders the movement of waxy crude oil is wax deposition in oil pipelines. To ensure the safe operation of crude oil pipelines, an accurate model must be developed to predict the rate of wax deposition in crude oil pipelines. Aiming at the shortcomings of the ENN prediction model, which easily falls into the local minimum value and weak generalization ability in the implementation process, an optimized ENN prediction model based on the IRSA is proposed. The validity of the new model was confirmed by the accurate prediction of two sets of experimental data on wax deposition… More > Graphic Abstract

    Prediction Model of Wax Deposition Rate in Waxy Crude Oil Pipelines by Elman Neural Network Based on Improved Reptile Search Algorithm

  • Open Access

    EDITORIAL

    Femoral Access with Ultrasound-Guided Puncture and Z-Stitch Hemostasis for Adults with Congenital Heart Diseases Undergoing Electrophysiological Procedures

    Fu Guan1,*, Matthias Gass2, Florian Berger2, Heiko Schneider1, Firat Duru1,3, Thomas Wolber1,3,*

    Congenital Heart Disease, Vol.19, No.1, pp. 85-92, 2024, DOI:10.32604/chd.2024.047266

    Abstract Aims: Although the application of ultrasound-guided vascular puncture and Z-stitch hemostasis to manage femoral access has been widely utilized, there is limited data on this combined application in adult congenital heart disease (ACHD) patients undergoing electrophysiological (EP) procedures. We sought to evaluate the safety and efficacy of ultrasound-guided puncture and postprocedural Z-stitch hemostasis for ACHD patients undergoing EP procedures. Methods and Results: The population of ACHD patients undergoing transfemoral EP procedures at the University of Zurich Heart Center between January 2019 and December 2022 was observed and analyzed. During the study period, femoral access (left/right, arterial/venous) was performed under real-time… More >

  • Open Access

    ARTICLE

    Degradation of FAK-targeting by proteolytic targeting chimera technology to inhibit the metastasis of hepatocellular carcinoma

    XINFENG ZHANG1,2,#, SHUANG LI2,#, MEIRU SONG1,2, YUE CHEN3, LIANGZHENG CHANG3, ZHERUI LIU4, HONGYUAN DAI3, YUTAO WANG4, GANGQI YANG3, YUN JIANG5,6,*, YINYING LU1,2,*

    Oncology Research, Vol.32, No.4, pp. 679-690, 2024, DOI:10.32604/or.2024.046231

    Abstract Liver cancer is a prevalent malignant cancer, ranking third in terms of mortality rate. Metastasis and recurrence primarily contribute to the high mortality rate of liver cancer. Hepatocellular carcinoma (HCC) has low expression of focal adhesion kinase (FAK), which increases the risk of metastasis and recurrence. Nevertheless, the efficacy of FAK phosphorylation inhibitors is currently limited. Thus, investigating the mechanisms by which FAK affects HCC metastasis to develop targeted therapies for FAK may present a novel strategy to inhibit HCC metastasis. This study examined the correlation between FAK expression and the prognosis of HCC. Additionally, we explored the impact of… More >

  • Open Access

    ARTICLE

    Developing risk models and subtypes of autophagy-associated LncRNAs for enhanced prognostic prediction and precision in therapeutic approaches for liver cancer patients

    LU ZHANG*, JINGUO CHU*, YUSHAN YU

    Oncology Research, Vol.32, No.4, pp. 703-716, 2024, DOI:10.32604/or.2023.030988

    Abstract Background: Limited research has been conducted on the influence of autophagy-associated long non-coding RNAs (ARLncRNAs) on the prognosis of hepatocellular carcinoma (HCC). Methods: We analyzed 371 HCC samples from TCGA, identifying expression networks of ARLncRNAs using autophagy-related genes. Screening for prognostically relevant ARLncRNAs involved univariate Cox regression, Lasso regression, and multivariate Cox regression. A Nomogram was further employed to assess the reliability of Riskscore, calculated from the signatures of screened ARLncRNAs, in predicting outcomes. Additionally, we compared drug sensitivities in patient groups with differing risk levels and investigated potential biological pathways through enrichment analysis, using consensus clustering to identify subgroups… More >

  • Open Access

    REVIEW

    CHARACTERISTICS OF MICROLAYER FORMATION AND HEAT TRANSFER IN MINI/MICROCHANNEL BOILING SYSTEMS: A REVIEW

    Yaohua Zhanga,*, Yoshio Utakab

    Frontiers in Heat and Mass Transfer, Vol.3, No.1, pp. 1-12, 2012, DOI:10.5098/hmt.v3.1.3003

    Abstract This paper reviews recent research on microlayer formed by confined vapor bubbles during boiling in mini/microchannels. Experimental measurements, simulations and theoretical studies are described and compared. As a reference to clarify the mechanism for the formation of a microlayer, Taylor flow (i.e. elongated bubble flow in mini/micro circular tubes under adiabatic conditions and at Re << 1) and elongated bubble flow at high velocity, with consideration of the influence of inertia, are also reviewed. Compared to the steady adiabatic conditions, one of the distinct points for the boiling condition is that the bubble grows exponentially due to rapid evaporation of… More >

  • Open Access

    ARTICLE

    Transparent and Accurate COVID-19 Diagnosis: Integrating Explainable AI with Advanced Deep Learning in CT Imaging

    Mohammad Mehedi Hassan1,*, Salman A. AlQahtani2, Mabrook S. AlRakhami1, Ahmed Zohier Elhendi3

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3101-3123, 2024, DOI:10.32604/cmes.2024.047940

    Abstract In the current landscape of the COVID-19 pandemic, the utilization of deep learning in medical imaging, especially in chest computed tomography (CT) scan analysis for virus detection, has become increasingly significant. Despite its potential, deep learning’s “black box” nature has been a major impediment to its broader acceptance in clinical environments, where transparency in decision-making is imperative. To bridge this gap, our research integrates Explainable AI (XAI) techniques, specifically the Local Interpretable Model-Agnostic Explanations (LIME) method, with advanced deep learning models. This integration forms a sophisticated and transparent framework for COVID-19 identification, enhancing the capability of standard Convolutional Neural Network… More >

  • Open Access

    ARTICLE

    Color and Gloss Changes of a Lignin-Based Polyurethane Coating under Accelerated Weathering

    Fatemeh Hassani Khorshidi1, Saeed Kazemi Najafi1, Farhood Najafi2,*, Antonio Pizzi3,*, Dick Sandberg4, Rabi Behrooz1

    Journal of Renewable Materials, Vol.12, No.2, pp. 305-323, 2024, DOI:10.32604/jrm.2023.043953

    Abstract The purpose of this research study was to investigate the properties of polyurethane coatings based on lignin nano-particles. For this purpose, the prepared coatings were applied to pine wood surfaces and weathered artificially. Subsequently, color and gloss of the coatings were measured before and after the weathering test. Field emission scanning electron microscopy (FE-SEM) micrographs prepared from the coatings showed that the average size of nano-particles in the polyurethane substrate was approximately 500 nm. Nuclear magnetic resonance (13C-NMR) spectroscopy showed that strong urethane bonds were formed in the nano-lignin-based polyurethane. Differential calorimetric analysis (DSC) test revealed that the glass-transition temperature… More > Graphic Abstract

    Color and Gloss Changes of a Lignin-Based Polyurethane Coating under Accelerated Weathering

  • Open Access

    ARTICLE

    Evaluation of the Antibacterial and Antifungal Capacity of Nanoemulsions Loaded with Synthetic Chalcone Derivatives Di-Benzyl Cinnamaldehyde and Benzyl 4-Aminochalcone

    Flavia Oliveira Monteiro da Silva Abreu1,2,*, Taysse Holanda1, Joice Farias do Nascimento1, Henety Nascimento Pinheiro1, Rachel Menezes Castelo1, Hélcio Silva dos Santos3, Thais Benincá4, Patrícia da Silva Malheiros4, Júlio César Sousa Prado5, Raquel de Oliveira Fontenelle5, Maria Madalena de Camargo Forte2

    Journal of Renewable Materials, Vol.12, No.2, pp. 285-304, 2024, DOI:10.32604/jrm.2023.043919

    Abstract With the increase in antimicrobial resistance, it has become necessary to explore alternative approaches for combating and preventing diseases. DB-cinnamaldehyde (CNM) and Benzyl4-amino (B4AM) are bioactive compounds derived from chalcones but with restricted solubility in aqueous media. Nanoemulsions can enhance the solubility of compounds and can be a promising alternative in the development of novel antimicrobials, with reduced side effects and prolonged release. The objective of this study was to evaluate the stability of oil-in-water nanoemulsions loaded with two distinct types of chalcones at two different dosages, to propose a stable formulation with antimicrobial properties. Results showed that nanoemulsions presented… More > Graphic Abstract

    Evaluation of the Antibacterial and Antifungal Capacity of Nanoemulsions Loaded with Synthetic Chalcone Derivatives Di-Benzyl Cinnamaldehyde and Benzyl 4-Aminochalcone

  • Open Access

    ARTICLE

    ASLP-DL —A Novel Approach Employing Lightweight Deep Learning Framework for Optimizing Accident Severity Level Prediction

    Saba Awan1,*, Zahid Mehmood2,*

    CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 2535-2555, 2024, DOI:10.32604/cmc.2024.047337

    Abstract Highway safety researchers focus on crash injury severity, utilizing deep learning—specifically, deep neural networks (DNN), deep convolutional neural networks (D-CNN), and deep recurrent neural networks (D-RNN)—as the preferred method for modeling accident severity. Deep learning’s strength lies in handling intricate relationships within extensive datasets, making it popular for accident severity level (ASL) prediction and classification. Despite prior success, there is a need for an efficient system recognizing ASL in diverse road conditions. To address this, we present an innovative Accident Severity Level Prediction Deep Learning (ASLP-DL) framework, incorporating DNN, D-CNN, and D-RNN models fine-tuned through iterative hyperparameter selection with Stochastic… More >

  • Open Access

    ARTICLE

    A Trust Evaluation Mechanism Based on Autoencoder Clustering Algorithm for Edge Device Access of IoT

    Xiao Feng1,2,3,*, Zheng Yuan1

    CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 1881-1895, 2024, DOI:10.32604/cmc.2023.047243

    Abstract First, we propose a cross-domain authentication architecture based on trust evaluation mechanism, including registration, certificate issuance, and cross-domain authentication processes. A direct trust evaluation mechanism based on the time decay factor is proposed, taking into account the influence of historical interaction records. We weight the time attenuation factor to each historical interaction record for updating and got the new historical record data. We refer to the beta distribution to enhance the flexibility and adaptability of the direct trust assessment model to better capture time trends in the historical record. Then we propose an autoencoder-based trust clustering algorithm. We perform feature… More >

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