Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (9)
  • Open Access


    Prevalence of Congenital Heart Disease at Extremely High Altitudes in Tibet and the Establishment of a New Free Treatment Model

    Shuting Chang1,2, Guanzhao Zhang2,3, Nengjun Sun2, Xinpeng Yuan4, Qingting Wang5, Lin Zhu6, Feiyue Zhang7, Yu Xiu4, Yang Dong8, Yonghong Chen9, Zhanpeng Zhao10, Xiao Liu4, Qiang Shao11, Xiaofeng Xu12, Anshun Wang13, Mengjiao Li14, Bo Li2,*

    Congenital Heart Disease, Vol.17, No.6, pp. 709-716, 2022, DOI:10.32604/chd.2022.018657

    Abstract Background: This study aimed to illustrate the prevalence of CHD by screening children in extremely high-altitude areas (over 4000 m to even 5000 m above sea level) and explore an aid model for early diagnosis and treatment for the Tibetan population. Methods: A total of 2242 students from different schools in Ngamring County, Xigaze city, Tibet from September 2019 to September 2020 were selected for screening. The students were examined through the inquiry of their current medical history and family history, cardiac auscultation and a physical examination, in order to screen out the suspected cases of CHD, and then the… More >

  • Open Access


    Multimodal Imaging with 3D-Holograms for Preoperative Planning in Pediatric Cardiac Surgery: A Unique Case Report

    Federica Caldaroni1, Massimo Chessa2, Alessandro Varrica1, Alessandro Giamberti1,*

    Congenital Heart Disease, Vol.17, No.4, pp. 491-494, 2022, DOI:10.32604/chd.2022.019119

    Abstract Multimodal imaging, including augmented or mixed reality, transforms the physicians’ interaction with clinical imaging, allowing more accurate data interpretation, better spatial resolution, and depth perception of the patient’s anatomy. We successfully overlay 3D holographic visualization to magnetic resonance imaging images for preoperative decision making of a complex case of cardiac tumour in a 7-year-old girl. More >

  • Open Access


    Grid Search for Predicting Coronary Heart Disease by Tuning Hyper-Parameters

    S. Prabu1,*, B. Thiyaneswaran2, M. Sujatha3, C. Nalini4, Sujatha Rajkumar5

    Computer Systems Science and Engineering, Vol.43, No.2, pp. 737-749, 2022, DOI:10.32604/csse.2022.022739

    Abstract Diagnosing the cardiovascular disease is one of the biggest medical difficulties in recent years. Coronary cardiovascular (CHD) is a kind of heart and blood vascular disease. Predicting this sort of cardiac illness leads to more precise decisions for cardiac disorders. Implementing Grid Search Optimization (GSO) machine training models is therefore a useful way to forecast the sickness as soon as possible. The state-of-the-art work is the tuning of the hyperparameter together with the selection of the feature by utilizing the model search to minimize the false-negative rate. Three models with a cross-validation approach do the required task. Feature Selection based… More >

  • Open Access


    miR-208a Promotes Apoptosis in H9c2 Cardiomyocytes by Targeting GATA4

    Liying Gong1,2,3, Hongkun Jiang4, Guangrong Qiu1, Kailai Sun1,*

    Congenital Heart Disease, Vol.16, No.5, pp. 499-512, 2021, DOI:10.32604/CHD.2021.015831

    Abstract Background: microRNAs are crucial for cardiovascular development and are associated with congenital heart disease (CHD). Recent studies have shown that microRNAs play a role in heart development and is closely related to CHD. The present study investigated the underlying mechanism of microRNA-208a (miR-208a) in “simple” CHD. Material and Methods: Reverse transcription-quantitative PCR (RT-qPCR) demonstrated miR-208a expression levels in children with CHD (n = 27) compared with normal controls (n = 29), in cardiomyocytes from embryo 10 (E10) to post-birth (P7) and organs in adult rats in healthy rats. Apoptosis of H9c2 cells after transfection with miR-208a detected by TUNEL assay.… More >

  • Open Access


    Do we have the ACHD physician resources we need to care for the burgeoning ACHD population?

    Fatima M. Ezzeddine1, Tabitha Moe2, Georges Ephrem3, William Aaron Kay3

    Congenital Heart Disease, Vol.14, No.4, pp. 511-516, 2019, DOI:10.1111/chd.12771

    Abstract Background: Delivery of care to the adult congenital heart disease (ACHD) popula‐ tion has been limited by a shortage in the ACHD physician resources. There is limited data regarding the adequacy of the ACHD physician resources in the United States and our population estimates are extrapolated from Canadian data. Therefore, we proposed to evaluate the adequacy of ACHD physician: patient ratios in the United States at both national and regional levels.
    Methods: Data from the Adult Congenital Heart Association (ACHA) website along with metropolitan area and statewide population data from 2016 US Census Bureau estimates were analyzed. Physicians listed on… More >

  • Open Access


    Correlates of posttraumatic stress disorder in adults with congenital heart disease

    Bahareh Eslami1,2

    Congenital Heart Disease, Vol.12, No.3, pp. 357-363, 2017, DOI:10.1111/chd.12452

    Abstract Objective: The aims of this study were to compare the level of posttraumatic stress disorder between adults with and without congenital heart disease, and to examine the correlates of posttraumatic stress disorder (e.g., sociodemographics).
    Design: Cross-sectional.
    Setting: Two university-affiliated heart hospitals in Tehran, Iran.
    Patients: A sample of 347 adults with congenital heart disease aged 18–64 years (52% women), and 353 adults without congenital heart disease matched by sex and age (±2 years) was recruited. Outcome Measures: The PTSD Scale: Self-report version was used to assess the diagnosis and severity of posttraumatic stress disorder. Hierarchical multivariate logistic regression analyses were… More >

  • Open Access


    Residents’ understanding of adult congenital heart disease

    Paul Cooper1, Morgan Hindes2, Timothy M. Maul3,4, Stephen C. Cook5

    Congenital Heart Disease, Vol.12, No.3, pp. 309-314, 2017, DOI:10.1111/chd.12441

    Abstract Objective: Medical residents are exposed to increasing numbers of adults with congenital heart disease (ACHD). While inadequate ACHD knowledge may lead to inappropriate practice, this educational deficit has not been investigated. Our aim was to analyze residents’ attitudes, perceived ability, and knowledge of ACHD medicine.
    Design, Methods, Outcome Measures: A single center, multiprogram cross-sectional study was conducted in 2015 using an electronic survey to assess 472 medical residents’ perceived knowledge and self-assessed skills related to ACHD medicine. Demographic data obtained included age, gender, level of training and program type.
    Results: The survey was completed by 25% of surveyed residents (N… More >

  • Open Access


    Determinants of platelet count in pediatric patients with congenital cyanotic heart disease: Role of immature platelet fraction

    Randa M. Matter1, Iman A. Ragab1, Alaa M. Roushdy2, Ahmed G. Ahmed1, Hanan H. Aly1, Eman A. Ismail3

    Congenital Heart Disease, Vol.13, No.1, pp. 118-123, 2018, DOI:10.1111/chd.12530

    Abstract Objectives: Congenital heart defects are common noninfectious causes of mortality in children. Bleeding and thrombosis are both limiting factors in the management of such patients. We assessed the frequency of thrombocytopenia in pediatric patients with congenital cyanotic heart disease (CCHD) and evaluated determinants of platelet count including immature platelet fraction (IPF) and their role in the pathogenesis of thrombocytopenia.
    Methods: Forty-six children and adolescents with CCHD during pre-catheter visits were studied; median age was 20.5 months. Complete blood count including IPF as a marker of platelet production and reticulated hemoglobin content (RET-He) as a marker of red cell production and… More >

  • Open Access


    Ancillary referral patterns in infants after initial assessment in a cardiac developmental outcomes clinic

    Sonia A. Monteiro1, Faridis Serrano1, Rocky Tsang1, Eboni Smith Hollier1, Danielle Guffey2, Lisa Noll1, Robert G. Voigt1, Nancy Ghanayem1, Lara Shekerdemian1

    Congenital Heart Disease, Vol.14, No.5, pp. 797-802, 2019, DOI:10.1111/chd.12789

    Abstract Objective: Neurodevelopmental impairment is common after surgery for congeni‐ tal heart disease (CHD) in infancy. While neurodevelopmental follow‐up of high‐risk patients has increased, the referral patterns for ancillary services following initial evaluation have not been reported. The aim of this study is to describe the rates and patterns of referral at the initial visit to our outcomes clinic of patients who under‐ went surgery for CHD during infancy.
    Outcomes Measures: The Cardiac Developmental Outcomes Program clinic at Texas Children’s Hospital provides routine longitudinal follow‐up with developmental pedi‐ atricians and child psychologists for children who required surgery for CHD within the… More >

Displaying 1-10 on page 1 of 9. Per Page