Nagaraju Pacharla, K. Srinivasa Reddy^*

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 3089-3110, 2024, DOI:10.32604/cmc.2024.048133

Abstract With the recent technological developments, massive vehicular ad hoc networks (VANETs) have been established, enabling numerous vehicles and their respective Road Side Unit (RSU) components to communicate with one another. The best way to enhance traffic flow for vehicles and traffic management departments is to share the data they receive. There needs to be more protection for the VANET systems. An effective and safe method of outsourcing is suggested, which reduces computation costs by achieving data security using a homomorphic mapping based on the conjugate operation of matrices. This research proposes a VANET-based data outsourcing system to fix the issues.… More >

Han Zhou^1,2, Hongtao Xu^1,2, Xinyue Chang^1,2, Wei Zhang^1,2, Heng Dong^1,2,*

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2295-2313, 2024, DOI:10.32604/cmc.2024.047754

Abstract Many deep learning-based registration methods rely on a single-stream encoder-decoder network for computing deformation fields between 3D volumes. However, these methods often lack constraint information and overlook semantic consistency, limiting their performance. To address these issues, we present a novel approach for medical image registration called the Dual-VoxelMorph, featuring a dual-channel cross-constraint network. This innovative network utilizes both intensity and segmentation images, which share identical semantic information and feature representations. Two encoder-decoder structures calculate deformation fields for intensity and segmentation images, as generated by the dual-channel cross-constraint network. This design facilitates bidirectional communication between grayscale and segmentation information, enabling the… More >

Imad Saud Al Naimi^1,2,*, Syed Alwee Aljunid Syed Junid¹, Muhammad lmran Ahmad^1,*, K. Suresh Manic^2,3

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2585-2608, 2024, DOI:10.32604/cmc.2024.046461

Abstract Augmentation of abnormal cells in the brain causes brain tumor (BT), and early screening and treatment will reduce its harshness in patients. BT’s clinical level screening is usually performed with Magnetic Resonance Imaging (MRI) due to its multi-modality nature. The overall aims of the study is to introduce, test and verify an advanced image processing technique with algorithms to automatically extract tumour sections from brain MRI scans, facilitating improved accuracy. The research intends to devise a reliable framework for detecting the BT region in the two-dimensional (2D) MRI slice, and identifying its class with improved accuracy. The methodology for the… More >

Umi Salma Basha¹, Shashi Kant Gupta², Wedad Alawad³, SeongKi Kim^4,*, Salil Bharany^5,*

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 3397-3416, 2024, DOI:10.32604/cmc.2024.046265

Abstract A new era of data access and management has begun with the use of cloud computing in the healthcare industry. Despite the efficiency and scalability that the cloud provides, the security of private patient data is still a major concern. Encryption, network security, and adherence to data protection laws are key to ensuring the confidentiality and integrity of healthcare data in the cloud. The computational overhead of encryption technologies could lead to delays in data access and processing rates. To address these challenges, we introduced the Enhanced Parallel Multi-Key Encryption Algorithm (EPM-KEA), aiming to bolster healthcare data security and facilitate… More >

Wajdi Alhakami^*

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 3211-3237, 2024, DOI:10.32604/cmc.2023.043935

Abstract The Kingdom of Saudi Arabia (KSA) has achieved significant milestones in cybersecurity. KSA has maintained solid regulatory mechanisms to prevent, trace, and punish offenders to protect the interests of both individual users and organizations from the online threats of data poaching and pilferage. The widespread usage of Information Technology (IT) and IT Enable Services (ITES) reinforces security measures. The constantly evolving cyber threats are a topic that is generating a lot of discussion. In this league, the present article enlists a broad perspective on how cybercrime is developing in KSA at present and also takes a look at some of… More >

YI HU^1,#, ZHONGYANG REN^2,#, ZHENGZHONG ZHAO¹, YONGJIA HUANG³, WANTING HUANG³, JIE LIU^3,*, LING DING^3,*

BIOCELL, Vol.48, No.5, pp. 745-758, 2024, DOI:10.32604/biocell.2024.049140

Abstract Background: Acute pancreatitis (AP), known for its rapid onset and significant incidence and mortality rates, presents a clinical challenge due to the limited availability of effective treatments and preventive measures. Anemarsaponin B (ASB) has emerged as a potential therapeutic agent, demonstrating capabilities in reducing immune inflammation, positioning it as a promising candidate for AP treatment. Methods: We investigated the effects of ASB on AP in mice, induced by caerulein and lipopolysaccharide (LPS). Peripheral blood samples were collected 24 h post-induction with caerulein to assess of key biomarkers including lipase, amylase, TNF-α, IL-1β, IL-6, SOD, and GSH-Px. A range of techniques… More >

YUANYUAN LI¹, BITAO ZHANG¹, ZILONG CUI¹, PEIJIAN FAN¹, SHAOXIAN WANG^1,2,*

BIOCELL, Vol.48, No.5, pp. 731-744, 2024, DOI:10.32604/biocell.2024.048820

Abstract Background: Depression is becoming increasingly prevalent around the world, imposing a substantial burden on individuals, families, as well as society. Quercetin is known to be highly effective in treating depression. However, additional research is needed to dissect the mechanisms of its anti-depressive effects. Methods: For this study, Sprague-Dawley (SD) rats were randomized into the control, model, quercetin, or fluoxetine group. The latter three groups were exposed to chronic unpredictable mild stress (CUMS) for 42 d. The first two groups received saline solution daily via oral gavage. Meanwhile, the quercetin group was orally administered a quercetin suspension (52.08 mg/kg) every day,… More >

KAIWEN TIAN^#, HANZHONG CHEN^#, QIANQIAN WANG, FENGLIAN JIANG, CHUNXIANG FENG, TENG LI, XIAOYONG PU, YANLIN TANG^*, JIUMIN LIU^*

BIOCELL, Vol.48, No.5, pp. 817-834, 2024, DOI:10.32604/biocell.2024.048737

Abstract Background: The incidence of clear cell renal cell carcinoma (ccRCC) is globally high; however, despite the introduction of innovative drug therapies, there remains a lack of effective biomarkers for evaluating treatment response. Recently, Caspase recruiting domain-containing protein 11 (CARD11) has garnered attention due to its significant association with tumor development and the immune system. Methods: The expression of CARD11 mRNA and protein in ccRCC were analyzed by public database and immunohistochemistry. The focus of this study is on the epigenomic modifications of CARD11, its expression of ccRCC immunophenotype, and its correlation with response to immunotherapy and targeted therapy. Furthermore, to… More > Graphic Abstract

XINRU FENG¹, LI XIAO^2,*

BIOCELL, Vol.48, No.5, pp. 793-801, 2024, DOI:10.32604/biocell.2024.048395

Abstract Background: Galectin 2 (LGALS2) is a protein previously reported to serve as a mediator of disease progression in a range of cancers. The function of LGALS2 in oral squamous cell carcinoma (OSCC), however, has yet to be explored, prompting the present study to address this literature gap. Methods: Overall, 144 paired malignant tumor tissues and paracancerous OSCC patient samples were harvested and the LGALS2 expression levels were examined through qPCR and western immunoblotting. The LGALS2 coding sequence was introduced into the pcDNA3.0 vector, to enable the overexpression of this gene, while an LGALS2-specific shRNA and corresponding controls were also obtained.… More >

Muhammad Waleed Ayub Ghouri¹, Guofeng Wang², Muhammad Ali Hussain³, Zhisheng Li^1,*, Tachia Chin¹

International Journal of Mental Health Promotion, Vol.26, No.4, pp. 279-292, 2024, DOI:10.32604/ijmhp.2024.044759

Abstract Crises in the past have caused devastating, long-lasting impacts on the global economy. The after-effects always bring some dynamic and rigorous challenges for businesses and governments. Such challenges have always been a point of discussion for scholars. The recent COVID-19 pandemic emaciated the global economy, leaving everyone mired in uncertainty, fear, and psychological impairments. One of the headwind features utilized by consumers during pandemic was panic buying (PB), which must be explored in various contexts for policymakers and practitioners. To address this gap, this study deployed a moderated mediation mechanism, integrating the health belief model (HBM) and competitive arousal theory… More >