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  • Open Access

    ARTICLE

    HybridFusionNet with Explanability: A Novel Explainable Deep Learning-Based Hybrid Framework for Enhanced Skin Lesion Classification Using Dermoscopic Images

    Mohamed Hammad1,2,*, Mohammed ElAffendi1, Souham Meshoul3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 1055-1086, 2025, DOI:10.32604/cmes.2025.072650 - 30 October 2025

    Abstract Skin cancer is among the most common malignancies worldwide, but its mortality burden is largely driven by aggressive subtypes such as melanoma, with outcomes varying across regions and healthcare settings. These variations emphasize the importance of reliable diagnostic technologies that support clinicians in detecting skin malignancies with higher accuracy. Traditional diagnostic methods often rely on subjective visual assessments, which can lead to misdiagnosis. This study addresses these challenges by developing HybridFusionNet, a novel model that integrates Convolutional Neural Networks (CNN) with 1D feature extraction techniques to enhance diagnostic accuracy. Utilizing two extensive datasets, BCN20000 and… More >

  • Open Access

    ARTICLE

    Robust Skin Cancer Detection through CNN-Transformer-GRU Fusion and Generative Adversarial Network Based Data Augmentation

    Alex Varghese1, Achin Jain2, Mohammed Inamur Rahman3, Mudassir Khan4,*, Arun Kumar Dubey2, Iqrar Ahmad5, Yash Prakash Narayan1, Arvind Panwar6, Anurag Choubey7, Saurav Mallik8,9,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.2, pp. 1767-1791, 2025, DOI:10.32604/cmes.2025.067999 - 31 August 2025

    Abstract Skin cancer remains a significant global health challenge, and early detection is crucial to improving patient outcomes. This study presents a novel deep learning framework that combines Convolutional Neural Networks (CNNs), Transformers, and Gated Recurrent Units (GRUs) for robust skin cancer classification. To address data set imbalance, we employ StyleGAN3-based synthetic data augmentation alongside traditional techniques. The hybrid architecture effectively captures both local and global dependencies in dermoscopic images, while the GRU component models sequential patterns. Evaluated on the HAM10000 dataset, the proposed model achieves an accuracy of 90.61%, outperforming baseline architectures such as VGG16 More >

  • Open Access

    ARTICLE

    Cyber-Integrated Predictive Framework for Gynecological Cancer Detection: Leveraging Machine Learning on Numerical Data amidst Cyber-Physical Attack Resilience

    Muhammad Izhar1,*, Khadija Parwez2, Saman Iftikhar3, Adeel Ahmad4, Shaikhan Bawazeer3, Saima Abdullah4

    Journal on Artificial Intelligence, Vol.7, pp. 55-83, 2025, DOI:10.32604/jai.2025.062479 - 25 April 2025

    Abstract The growing intersection of gynecological cancer diagnosis and cybersecurity vulnerabilities in healthcare necessitates integrated solutions that address both diagnostic accuracy and data protection. With increasing reliance on IoT-enabled medical devices, digital twins, and interconnected healthcare systems, the risk of cyber-physical attacks has escalated significantly. Traditional approaches to machine learning (ML)–based diagnosis often lack real-time threat adaptability and privacy preservation, while cybersecurity frameworks fall short in maintaining clinical relevance. This study introduces HealthSecureNet, a novel Cyber-Integrated Predictive Framework designed to detect gynecological cancer and mitigate cybersecurity threats in real time simultaneously. The proposed model employs a… More >

  • Open Access

    ARTICLE

    xCViT: Improved Vision Transformer Network with Fusion of CNN and Xception for Skin Disease Recognition with Explainable AI

    Armughan Ali1,2, Hooria Shahbaz2, Robertas Damaševičius3,*

    CMC-Computers, Materials & Continua, Vol.83, No.1, pp. 1367-1398, 2025, DOI:10.32604/cmc.2025.059301 - 26 March 2025

    Abstract Skin cancer is the most prevalent cancer globally, primarily due to extensive exposure to Ultraviolet (UV) radiation. Early identification of skin cancer enhances the likelihood of effective treatment, as delays may lead to severe tumor advancement. This study proposes a novel hybrid deep learning strategy to address the complex issue of skin cancer diagnosis, with an architecture that integrates a Vision Transformer, a bespoke convolutional neural network (CNN), and an Xception module. They were evaluated using two benchmark datasets, HAM10000 and Skin Cancer ISIC. On the HAM10000, the model achieves a precision of 95.46%, an… More >

  • Open Access

    ARTICLE

    An Enhanced Lung Cancer Detection Approach Using Dual-Model Deep Learning Technique

    Sumaia Mohamed Elhassan1, Saad Mohamed Darwish1,*, Saleh Mesbah Elkaffas2

    CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.1, pp. 835-867, 2025, DOI:10.32604/cmes.2024.058770 - 17 December 2024

    Abstract Lung cancer continues to be a leading cause of cancer-related deaths worldwide, emphasizing the critical need for improved diagnostic techniques. Early detection of lung tumors significantly increases the chances of successful treatment and survival. However, current diagnostic methods often fail to detect tumors at an early stage or to accurately pinpoint their location within the lung tissue. Single-model deep learning technologies for lung cancer detection, while beneficial, cannot capture the full range of features present in medical imaging data, leading to incomplete or inaccurate detection. Furthermore, it may not be robust enough to handle the… More >

  • Open Access

    ARTICLE

    Multi-Class Skin Cancer Detection Using Fusion of Textural Features Based CAD Tool

    Khushmeen Kaur Brar1, Bhawna Goyal1, Ayush Dogra2, Sampangi Rama Reddy3, Ahmed Alkhayyat4, Rajesh Singh5, Manob Jyoti Saikia6,7,*

    CMC-Computers, Materials & Continua, Vol.81, No.3, pp. 4217-4263, 2024, DOI:10.32604/cmc.2024.052548 - 19 December 2024

    Abstract Skin cancer has been recognized as one of the most lethal and complex types of cancer for over a decade. The diagnosis of skin cancer is of paramount importance, yet the process is intricate and challenging. The analysis and modeling of human skin pose significant difficulties due to its asymmetrical nature, the visibility of dense hair, and the presence of various substitute characteristics. The texture of the epidermis is notably different from that of normal skin, and these differences are often evident in cases of unhealthy skin. As a consequence, the development of an effective… More >

  • Open Access

    ARTICLE

    Enhancing Early Detection of Lung Cancer through Advanced Image Processing Techniques and Deep Learning Architectures for CT Scans

    Nahed Tawfik1,*, Heba M. Emara2, Walid El-Shafai3, Naglaa F. Soliman4, Abeer D. Algarni4, Fathi E. Abd El-Samie4

    CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 271-307, 2024, DOI:10.32604/cmc.2024.052404 - 15 October 2024

    Abstract Lung cancer remains a major concern in modern oncology due to its high mortality rates and multifaceted origins, including hereditary factors and various clinical changes. It stands as the deadliest type of cancer and a significant cause of cancer-related deaths globally. Early diagnosis enables healthcare providers to administer appropriate treatment measures promptly and accurately, leading to improved prognosis and higher survival rates. The significant increase in both the incidence and mortality rates of lung cancer, particularly its ranking as the second most prevalent cancer among women worldwide, underscores the need for comprehensive research into efficient… More >

  • Open Access

    ARTICLE

    Integrating Transformer and Bidirectional Long Short-Term Memory for Intelligent Breast Cancer Detection from Histopathology Biopsy Images

    Prasanalakshmi Balaji1,*, Omar Alqahtani1, Sangita Babu2, Mousmi Ajay Chaurasia3, Shanmugapriya Prakasam4

    CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.1, pp. 443-458, 2024, DOI:10.32604/cmes.2024.053158 - 20 August 2024

    Abstract Breast cancer is a significant threat to the global population, affecting not only women but also a threat to the entire population. With recent advancements in digital pathology, Eosin and hematoxylin images provide enhanced clarity in examining microscopic features of breast tissues based on their staining properties. Early cancer detection facilitates the quickening of the therapeutic process, thereby increasing survival rates. The analysis made by medical professionals, especially pathologists, is time-consuming and challenging, and there arises a need for automated breast cancer detection systems. The upcoming artificial intelligence platforms, especially deep learning models, play an More >

  • Open Access

    RETRACTION

    Retraction: Deep Belief Network for Lung Nodule Segmentation and Cancer Detection

    Computer Systems Science and Engineering Editorial Office

    Computer Systems Science and Engineering, Vol.48, No.4, pp. 1083-1083, 2024, DOI:10.32604/csse.2024.054265 - 17 July 2024

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Machine Learning Techniques Using Deep Instinctive Encoder-Based Feature Extraction for Optimized Breast Cancer Detection

    Vaishnawi Priyadarshni1, Sanjay Kumar Sharma1, Mohammad Khalid Imam Rahmani2,*, Baijnath Kaushik3, Rania Almajalid2,*

    CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 2441-2468, 2024, DOI:10.32604/cmc.2024.044963 - 27 February 2024

    Abstract Breast cancer (BC) is one of the leading causes of death among women worldwide, as it has emerged as the most commonly diagnosed malignancy in women. Early detection and effective treatment of BC can help save women’s lives. Developing an efficient technology-based detection system can lead to non-destructive and preliminary cancer detection techniques. This paper proposes a comprehensive framework that can effectively diagnose cancerous cells from benign cells using the Curated Breast Imaging Subset of the Digital Database for Screening Mammography (CBIS-DDSM) data set. The novelty of the proposed framework lies in the integration of More >

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