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  • Open Access

    REVIEW

    Revolutionizing Metabolic Engineering in Cannabis sativa L.: Harnessing the Power of Hairy Root Culture

    Md. Injamum-Ul-Hoque1,2, Md. Mahfuzur Rahman2, Nayan Chandra Howlader3, Soosan Tavakoli4, Md. Mezanur Rahman5, Shahin Imran6, Mallesham Bulle7, S. M. Ahsan2,4,*, Hyong Woo Choi4,8,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3805-3826, 2025, DOI:10.32604/phyton.2025.069827 - 29 December 2025

    Abstract Cannabis sativa is highly valued for its use in fiber production, medicine, and recreational products. Its secondary metabolites (SM) are renowned for their wide range of health benefits and psychoactive properties. While much of the existing research has focused on cannabinoid production in the plant’s aerial parts, particularly the leaves and flowers, the root system remains understudied in terms of its SM profile. One promising in vitro approach for metabolite production involves the use of ‘hairy roots (HRs)’. These roots mimic the phytochemical profile of native roots but grow more efficiently and yield higher quantities of metabolites.… More >

  • Open Access

    ARTICLE

    Effect of Processing and Cultivar on Thermo-Chemical Properties of Australian-Grown Hemp Hurd (Cannabis sativa L.)

    Johannes Fehrmann1,*, Benoit Belleville1, Barbara Ozarska1, Maya Ismayati2, Wahyu Dwianto2

    Journal of Renewable Materials, Vol.12, No.8, pp. 1475-1493, 2024, DOI:10.32604/jrm.2024.053741 - 06 September 2024

    Abstract This study explored the thermo-chemical properties of industrial hemp hurd with different provenances, maturity stages, and retting protocols. The findings were then compared to hemp hurd used in the fabrication of citric acid-bonded ultra-low-density hemp hurd particleboard. Pyrolysis-gas chromatography-mass spectrometry (Py-GC/MS), Fourier-transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA) were employed to document the variability of the hurd and comprehend the potential impact on biobased composite applications. The choice of cultivar, maturity stage, and processing modality significantly influenced the chemical composition, presence of functional groups, and thermal stability of the hurd. Py-GC/MS revealed substantial variations… More > Graphic Abstract

    Effect of Processing and Cultivar on Thermo-Chemical Properties of Australian-Grown Hemp Hurd (<i>Cannabis sativa</i> L.)

  • Open Access

    VIEWPOINT

    Cannabis and male reproduction: Impact on offspring via sperm epigenome

    PAOLA GRIMALDI*

    BIOCELL, Vol.46, No.2, pp. 301-304, 2022, DOI:10.32604/biocell.2022.017588 - 20 October 2021

    Abstract Cannabis is the most widely used drug in the Western societies particularly among adolescent and young adults. Epidemiological studies demonstrate that men use cannabis more frequently than women with higher risk in developing cannabis-related disorders. Although the direct adverse effects of cannabis on male reproductive functions have been studied both in humans and animal models, the possible long-term risks for the health of the users and their offspring are still an area of active research. More >

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