KARAN WADHWA¹, PAYAL CHAUHAN¹, SHOBHIT KUMAR², RAKESH PAHWA^3,*, RAVINDER VERMA⁴, RAJAT GOYAL⁵, GOVIND SINGH¹, ARCHANA SHARMA⁶, NEHA RAO³, DEEPAK KAUSHIK^1,*

Oncology Research, Vol.32, No.5, pp. 877-897, 2024, DOI:10.32604/or.2024.047278

Abstract Background: Glioblastoma multiforme (GBM) is recognized as the most lethal and most highly invasive tumor. The high likelihood of treatment failure arises from the presence of the blood-brain barrier (BBB) and stem cells around GBM, which avert the entry of chemotherapeutic drugs into the tumor mass. Objective: Recently, several researchers have designed novel nanocarrier systems like liposomes, dendrimers, metallic nanoparticles, nanodiamonds, and nanorobot approaches, allowing drugs to infiltrate the BBB more efficiently, opening up innovative avenues to prevail over therapy problems and radiation therapy. Methods: Relevant literature for this manuscript has been collected from a comprehensive and systematic search of… More > Graphic Abstract

Cyril Enault^*

Revue Internationale de Géomatique, Vol.33, pp. 77-92, 2024, DOI:10.32604/rig.2024.046591

Abstract La théorie égocentrée est aujourd’hui bien connue des éthologues et des psychologues mais moins diffusée chez les géographes car elle reste encore à l’état de théorie abstraite. Ce papier se propose dans un premier temps de rendre opérationnel cette approche dans le cadre de travaux géographiques à l’échelle de l’individu. Puis, elle envisage d’établir le lien entre l’échelle individu et l’échelle de la ville avec comme objectif de produire des cartes déformées de la ville. More > Graphic Abstract

YARA ALZGHOUL, HALA J. BANI ISSA, AHMAD K. SANAJLEH, TAQWA ALABDUH, FATIMAH RABABAH, MAHA AL-SHDAIFAT, EJLAL ABU-EL-RUB^*, FATIMAH ALMAHASNEH, RAMADA R. KHASAWNEH, AYMAN ALZU’BI, HUTHAIFA MAGABLEH

BIOCELL, Vol.48, No.4, pp. 559-569, 2024, DOI:10.32604/biocell.2024.048056

Abstract Mesenchymal stem cells (MSCs) are ideal candidates for treating many cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function. More >

JIAN TANG¹, CHENQIANG ZHU¹, YUN CHEN¹, YUNLONG WU¹, MING HE¹, YI ZHOU², MINGHUA XIE^2,*

BIOCELL, Vol.48, No.4, pp. 639-651, 2024, DOI:10.32604/biocell.2024.047562

Abstract Background: The specific impact of sphingolipid metabolism on developing hepatocellular Carcinoma (HCC) remains unclear. This study aims to explore the relationship between sphingolipid metabolism and HCC prognosis, immune response, and drug sensitivity. Methods: Data were obtained from The Cancer Genome Atlas (TCGA)-Hepatocellular Carcinoma (LIHC) and Gene Expression Omnibus (GEO, GSE14520 datasets). 47 sphingolipid metabolism genes were obtained from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. After classifying HCC samples using the Non-negative Matrix Factorization (NMF) clustering method, differentially expressed genes were screened. Then, 8 risk genes were obtained by univariate analysis, survival random forest reduction and lasso analysis.… More > Graphic Abstract

LIJUAN ZHANG^1,#, QINGYIN MENG^2,#, LI ZHUANG¹, QUAN GONG¹, XIANDA HUANG³, XUEQIN LI¹, SHIJUAN LI¹, GUOQIN WANG⁴, XICAI WANG^5,*

BIOCELL, Vol.48, No.4, pp. 581-590, 2024, DOI:10.32604/biocell.2024.047260

Abstract Background: Lung adenocarcinoma is a very pervasive histological form of lung cancers, and inhibiting metastasis is crucial for effective treatment. In this investigation, we explored the functional interaction of miR-30a-5p and the putative transcription factor 2 of the homeodomain (PHTF2) in dictating the aggressiveness and metastasis of lung adenocarcinoma. Method: We collected clinical samples to evaluate the expression patterns of miR-30a-5p and PHTF2 in lung adenocarcinoma along with normal tissues. Cellular experiments including cell count kit (CCK)-8 growth assay, apoptosis analysis, migration and invasion examinations were performed to assess the aggressiveness of lung adenocarcinoma cells. Furthermore, we examined tumorigenesis and… More > Graphic Abstract

FEI KONG¹, QIYUAN TIAN², BINGLIN KUANG³, LILI SHANG⁴, XIAOXIAO ZHANG⁵, DONGYANG LI⁵, YING KONG^6,*

BIOCELL, Vol.48, No.4, pp. 665-675, 2024, DOI:10.32604/biocell.2024.046342

Abstract Introduction: Myocardial ischemia-reperfusion (IR) injury has received widespread attention due to its damaging effects. Electroacupuncture (EA) pretreatment has preventive effects on myocardial IR injury. SLC26A4 is a Na+ independent anion reverse transporter and has not been reported in myocardial IR injury. Objectives: To find potential genes that may be regulated by EA and explore the role of this gene in myocardial IR injury. Methods: RNA sequencing and bioinformatics analysis were performed to obtain the differentially expressed genes in the myocardial tissue of IR rats with EA pretreatment. Myocardial infarction size was detected by TTC staining. Serum CK, creatinine kinase-myocardial band,… More > Graphic Abstract

Liting Jia¹, Xiao Han¹, Cuixia Qiao², Gang Zhao², Yanzhi Xia¹, Zhixin Xue^1,*

Journal of Renewable Materials, Vol.12, No.3, pp. 427-441, 2024, DOI:10.32604/jrm.2023.044310

Abstract Ba²⁺ pre-crosslinked carrageenan fiber (Ba/CAF) was prepared by adding a small amount of Ba²⁺ to the carrageenan (CA) solution as the spinning solution. Ba/CAF-n/A, Ba/CAF-n/B and Ba/CAF-n/C were prepared with ethanol solution (combine A), high concentration BaCl₂ solution (combine B) and low concentration BaCl₂ solution (combine C), as coagulation bath and stretch bath, respectively. The combination of coagulation bath and stretch bath suitable for Ba²⁺ pre-crosslinking wet spinning was screened. The results showed that Ba²⁺ can induce the birefringence of the CA molecular chain, and the Ba²⁺ pre-crosslinking effect is the best when the CA mass fraction is 8.0 wt%.… More > Graphic Abstract

KAVITA^*, R.K. TIWARI

Journal of Polymer Materials, Vol.36, No.2, pp. 195-205, 2019, DOI:10.32381/JPM.2019.36.02.7

Abstract The effect of poly (vinyl butyral) and acid functionalized multiwalled carbon nanotubes (f-MWCNT) on the thermal and mechanical performance of Kevlar fiber reinforced novolac epoxy nanocomposites was investigated and presented in this paper. Nanocomposite containing 1.5 wt. % poly (vinyl butyral) and 0.5 wt. % f-MWCNT exhibited best thermal and mechanical properties (except flexural strength) among all the nanocomposites reported here. It showed ~5%, 27% and 126 % improvement in tensile strength, young’s modulus and impact strength respectively as compared to the neat novolac epoxy Kevlar composite.Nanocomposite containing 0.5 wt. % f- MWCNT and 2 wt. % poly (vinyl butyral)… More >

M. VASUMATHI^1,a,*, VELA MURALI^2,b, S. RASHIA BEGUM^1,c, N. RAJENDRAN^2,d

Journal of Polymer Materials, Vol.36, No.1, pp. 1-11, 2019, DOI:10.32381/JPM.2019.36.01.1

Abstract In the Fibre Metal Laminate (FML), Carbon Reinforced Aluminium laminate (CARALL), aluminium is placed next to carbon fibres. The potential difference between the aluminium and carbon is larger, leads to galvanic corrosion, which tries to bring down the durability of the FML. To bring down the effect of corrosion, a material layer is introduced between fibres and aluminium so as to separate them thus lowering the possibility of occurrence of corrosion. Another approach is to coat the surfaces of aluminium with different proportions of aluminium oxide nano particles prior to fabrication of the FML. For both the cases, corrosion rates… More >

A.K. GHOSH¹, RUTUJA S. BHOJE², R.C. BINDAL¹

Journal of Polymer Materials, Vol.37, No.1-2, pp. 109-120, 2020, DOI:10.32381/JPM.2020.37.1-2.8

Abstract In this study, cellulose triacetate (CTA) based nanocomposite membranes were developed by incorporation of carboxylic acid functionalized multiwalled carbon-nanotube (cMWCNT) and graphene oxide (GO) which have enhancement of both flux and fouling resistance properties of the membranes. Membranes were casted at room temperature and annealed at 90o C hot water for 10 minutes. The incorporation level of both the nanomaterials is 1.5% of the CTA polymer weight in the nanocomposite membranes. Prepared membranes were characterized in terms of water contact angle, surface morphology and mechanical strength. The performance of the membranes was evaluated both in reverse osmosis (RO) and forward… More >