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  • Open Access

    ARTICLE

    AGPAT3 Regulates Immune Microenvironment in Osteosarcoma via Lysophosphatidic Acid Metabolism

    Shenghui Su, Yu Zeng, Jiaxin Chen, Xieping Dong*

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070558 - 30 December 2025

    Abstract Background: Recent studies have shown glycerolipid metabolism played an essential role in multiple tumors, however, its function in osteosarcoma is unclear. This study aimed to explore the role of glycerolipid metabolism in osteosarcoma. Methods: We conducted bioinformatics analysis using data from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) database and single-cell RNA sequencing. Least Absolute Shrinkage and Selection Operator (LASSO) regression was used to identify the Glycerolipid metabolism-related genes associated with the clinical outcome of osteosarcoma. Tumor-associated macrophages (TAMs) and their interactions with immune cells were examined through single-cell analysis and co-culture experiments.… More >

  • Open Access

    ARTICLE

    Forecasting Modeling Tool of Crop Diseases across Multiple Scenarios: System Design, Implementation, and Applications

    Mintao Xu1,#, Zichao Jin1,#, Yangyang Tian1, Jingcheng Zhang1,*, Huiqin Ma1, Yujin Jing1, Jiangxing Wu2, Jing Zhai2

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4059-4078, 2025, DOI:10.32604/phyton.2025.074422 - 29 December 2025

    Abstract The frequent outbreaks of crop diseases pose a serious threat to global agricultural production and food security. Data-driven forecasting models have emerged as an effective approach to support early warning and management, yet the lack of user-friendly tools for model development remains a major bottleneck. This study presents the Multi-Scenario Crop Disease Forecasting Modeling System (MSDFS), an open-source platform that enables end-to-end model construction-from multi-source data ingestion and feature engineering to training, evaluation, and deployment-across four representative scenarios: static point-based, static grid-based, dynamic point-based, and dynamic grid-based. Unlike conventional frameworks, MSDFS emphasizes modeling flexibility, allowing… More >

  • Open Access

    ARTICLE

    Hydrothermal Synthesis of Lead Indium Selenide

    A. B. Rzayeva1,2,*, F. E. Abbdullayeva1, S. C. Imanova1, S. H. Aliyeva1,2, S. N. Yasinova1,2

    Chalcogenide Letters, Vol.22, No.11, pp. 965-970, 2025, DOI:10.15251/CL.2025.2211.965

    Abstract Lead indium selenide (PbIn2Se₄) is a promising chalcogenide semiconductor for optoelectronic and energy applications. We report a hydrothermal synthesis route using ethylene glycol under moderate conditions (433– 453 K, 7–12 h), yielding up to 85–87%. The product crystallized into a cotton-like morphology composed of nanoand microparticles. Structural and compositional integrity were confirmed by chemical analysis, thermogravimetric analysis, and transmission electron microscopy. These results demonstrate that hydrothermal synthesis provides an efficient and controllable pathway to high-purity PbIn2Se₄, opening opportunities for its use in advanced functional devices. More >

  • Open Access

    REVIEW

    Key Plant Transcription Factors in Crop Tolerance to Abiotic Stresses

    Nadia Lamsaadi1, Oumaima Maarouf2, Soukaina Lahmaoui2, Hamid Msaad2, Omar Farssi2, Chaima Hamim2, Mohamed Tamoudjout2, Hafsa Hirt2, Habiba Kamal2, Majida El Hassni2, Cherki Ghoulam3,4, Ahmed El Moukhtari5,*, Mohamed Farissi2

    Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3585-3610, 2025, DOI:10.32604/phyton.2025.072311 - 01 December 2025

    Abstract Abiotic stresses, such as drought, heavy metals, salinity, and extreme temperatures, are among the most common adverse threats that restrict the use of land for agriculture and limit crop growth and productivity. As sessile organisms, plants defend themselves from abiotic stresses by developing various tolerance mechanisms. These mechanisms are governed by several biochemical traits. The biochemical mechanisms are the products of key genes that express under specific conditions. Interestingly, the expression of these genes is regulated by specialized proteins known as transcription factors (TFs). Several TFs, including those from the bZIP, bHLH, MYB, HSF, WRKY,… More >

  • Open Access

    ARTICLE

    Genome-Wide Scanning Analysis for MYB and MADS in Hydrangea macrophylla and the Inflorescence Type Related Candidate Genes Expression Analysis

    Qunlu Liu1,#, Fiza Liaquat1,2,#, Qiqi Tang1, Jun Yang3,4, Shuai Qiu5, Amber Malik2, Kang Ye3,4, Kai Gao5, Jun Qin3,4,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3539-3562, 2025, DOI:10.32604/phyton.2025.071989 - 01 December 2025

    Abstract Hydrangea macrophylla is a popular ornamental shrub with a lot of economic and aesthetic value. It is known for its different flower shapes (lacecap and mophead) and the way its flowers change color depending on the pH of the soil. Even though it is important for gardening, we still don’t know much about the molecular processes that lead to flower growth. The purpose of this study was to find and study SNP-related genes and transcription factors that are connected to the growth of H. macrophylla flowers. Genome-wide SNP analysis identified 11 SNPs associated with MYB transcription factors… More >

  • Open Access

    REVIEW

    Recent Advancements in Biochar Functionalization from Crop Residues for a Green Future

    Omojola Awogbemi1,*, Daramy Vandi Von Kallon1, Ramesh C. Ray2

    Journal of Renewable Materials, Vol.13, No.11, pp. 2191-2233, 2025, DOI:10.32604/jrm.2025.02025-0112 - 24 November 2025

    Abstract Increased human and industrial activities have exacerbated the release of toxic materials and acute environmental pollution in recent times. Biochar, a carbon-rich material produced from biomass, is gaining momentum as a versatile material for attaining a sustainable environment. The study reviews the application of functionalized biochar for energy storage, environmental remediation, catalysis, and sustainable agriculture, aiming to achieve a greener future. The deployment of crop residues as a renewable feedstock for biochar, and their properties, compositions, modification, and functionalization techniques are also discussed. Additionally, the avenues for applying functionalized biochar to achieve a greener future,… More > Graphic Abstract

    Recent Advancements in Biochar Functionalization from Crop Residues for a Green Future

  • Open Access

    REVIEW

    3D LiDAR-Based Techniques and Cost-Effective Measures for Precision Agriculture: A Review

    Mukesh Kumar Verma1,2,*, Manohar Yadav1

    Revue Internationale de Géomatique, Vol.34, pp. 855-879, 2025, DOI:10.32604/rig.2025.069914 - 17 November 2025

    Abstract Precision Agriculture (PA) is revolutionizing modern farming by leveraging remote sensing (RS) technologies for continuous, non-destructive crop monitoring. This review comprehensively explores RS systems categorized by platform—terrestrial, airborne, and space-borne—and evaluates the role of multi-sensor fusion in addressing the spatial and temporal complexity of agricultural environments. Emphasis is placed on data from LiDAR, GNSS, cameras, and radar, alongside derived metrics such as plant height, projected leaf area, and biomass. The study also highlights the significance of data processing methods, particularly machine learning (ML) and deep learning (DL), in extracting actionable insights from large datasets. By More >

  • Open Access

    COMMENTARY

    CD47-Targeted Therapy in Cancer Immunotherapy: At a Crossroads of Promise and Challenge

    Xuejun Guo1,2, Yilin Fu3, Natalia Baran4,5, Wenxue Ma6,*

    Oncology Research, Vol.33, No.11, pp. 3375-3385, 2025, DOI:10.32604/or.2025.071708 - 22 October 2025

    Abstract Cluster of differentiation 47 (CD47), an immune checkpoint commonly referred to as the “don’t eat me” signal, plays a pivotal role in tumor immune evasion by inhibiting phagocytosis through interaction with signal regulatory protein alpha (SIRPα) on macrophages and dendritic cells (DCs). Although early enthusiasm drove broad clinical development, recent discontinuations of major CD47-targeted programs have prompted re-evaluation of its therapeutic potential. The purpose of this commentary is to contextualize the setbacks observed with first-generation CD47 inhibitors and to highlight strategies aimed at overcoming their limitations. Clinical challenges, including anemia, thrombocytopenia, suboptimal pharmacokinetics, and limited… More >

  • Open Access

    ARTICLE

    Effects of Microplastics on Growth Pattern of Pinus massoniana and Schima uperba

    Keke Zhang1,2,3, Yong Cui1,2,3, Changchang Shao1,2,3, Liqing Yang1,2,3, Yuxin Wang1,2,3, Yao Fang1,2,3, Hua Zhou4, Jie Wang1,2,3, Honglang Duan1,2,3,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.9, pp. 2855-2871, 2025, DOI:10.32604/phyton.2025.065683 - 30 September 2025

    Abstract As ubiquitous environmental contaminants, microplastics (MPs) have garnered global concern due to their persistence, bioaccumulation potential, and multifaceted threats to ecosystem health. These particles threaten terrestrial ecosystems via soil contamination; however, research on their phytotoxicity remains predominantly focused on herbaceous plants. The responses of woody plants to MPs and their interspecific differences are severely unexplored. Here, two important ecological and economical tree species in southern China, Pinus massoniana (P. massoniana) and Schima superba (S. superba), were selected to explore the ecotoxicity effects of polyethylene (PE) and polypropylene (PP) MPs (the two most abundant species in the soil) on… More >

  • Open Access

    REVIEW

    Unraveling the Functional Diversity of MYB Transcription Factors in Plants: A Systematic Review of Recent Advances

    Imene Tatar Caliskan1,2, George Dzorgbenya Ametefe3, Aziz Caliskan4, Su-Ee Lau1,5, Yvonne Jing Mei Liew6, Nur Kusaira Khairul Ikram5, Boon Chin Tan1,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.8, pp. 2229-2254, 2025, DOI:10.32604/phyton.2025.067225 - 29 August 2025

    Abstract Myeloblastosis (MYB) transcription factors (TFs) are evolutionarily conserved regulatory proteins that are crucial for plant growth, development, secondary metabolism, and stress adaptation. Recent studies have highlighted their crucial role in coordinating growth–defense trade-offs through transcriptional regulation of key biosynthetic and stress-response genes. Despite extensive functional characterization in model plants such as Arabidopsis thaliana, systematically evaluating the broader functional landscape of MYB TFs across diverse species and contexts remains necessary. This systematic review integrates results from 24 peer-reviewed studies sourced from Scopus and Web of Science, focusing on the functional diversity of MYB TFs, particularly in relation… More >

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