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  • Open Access

    ARTICLE

    Effect of Cartilage Endplate on Cell Based Disc Regeneration: A Finite Element Analysis

    Yongren Wu, Sarah Cisewski, Barton L. Sachs, Hai Yao∗,†,‡

    Molecular & Cellular Biomechanics, Vol.10, No.2, pp. 159-182, 2013, DOI:10.3970/mcb.2013.010.159

    Abstract This study examines the effects of cartilage endplate (CEP) calcification and the injection of intervertebral disc (IVD) cells on the nutrition distributions inside the human IVD under physiological loading conditions using multiphasic finite element modeling. The human disc was modeled as an inhomogeneous mixture consisting of a charged elastic solid, water, ions (Na+ and Cl), and nutrient solute(oxygen,glucose and lactate) phases. The effect of the endplate calcification was simulated by a reduction of the tissue porosity (i.e., water volume faction) from 0.60 to 0.48. The effect of cell injection was simulated by increasing the cell density in the nucleus pulposus… More >

  • Open Access

    ARTICLE

    Comparison of Hemodynamic Endpoints between Normal Subject and Tetralogy Patient Using Womersley Velocity Profile and MR Based Flow Measurements

    Ashish Das, William M. Gottliebson†,‡, Madhura Karve, Rupak Banerjee∗,§,¶

    Molecular & Cellular Biomechanics, Vol.8, No.1, pp. 21-42, 2011, DOI:10.3970/mcb.2011.008.021

    Abstract Right ventricular (RV) enlargement and pulmonary valve insufficiency (PI) are well-known, unavoidable long term sequelae encountered by patients who undergo tetralogy of Fallot (TOF) surgery. Despite their lifelong need for cardiac surveillance and occasional re-intervention, there is a paucity of numerical data characterizing blood flows in their pulmonary arteries (PA). Specifically, although PA regurgitation is well-known to be ubiquitously present in adult repaired TOF (rTOF) patients yet, there have been only limited numerical studies to fully characterize this process. The few studies available have utilized idealized, simplistic geometric models or overly simplistic boundary conditions that fail to account for flow… More >

  • Open Access

    ARTICLE

    Automated Synthesis of Wideband Bandpass Filters Based on Slow-wave EBG Structures

    Marco Orellana1, Jordi Selga1, Paris Vélez1, Marc Sans1, Ana Rodríguez2, Vicente Boria2, Ferran Martín1

    CMC-Computers, Materials & Continua, Vol.52, No.3, pp. 159-174, 2016, DOI:10.3970/cmc.2016.052.157

    Abstract This paper is focused on the automated synthesis of wideband bandpass filters operating at microwave frequencies and based on electromagnetic bandgap (EBG) structures. The classical counterpart of such filter consists of a combination of transmission line sections and shunt-connected grounded stubs placed at equidistant positions. By replacing the transmission line sections with capacitively-loaded lines (a kind of EBG-based lines) exhibiting the same phase shift at the lower cutoff frequency and the same characteristic (actually Bloch) impedance, filter size is reduced and the spurious pass bands can be efficiently suppressed. In practice, the loading capacitances are implemented by means of patches,… More >

  • Open Access

    ARTICLE

    A DPN (Delegated Proof of Node) Mechanism for Secure Data Transmission in IoT Services

    Dae-Young Kim1, Se Dong Min2, †, Seokhoon Kim3, †, *

    CMC-Computers, Materials & Continua, Vol.60, No.1, pp. 1-14, 2019, DOI:10.32604/cmc.2019.06102

    Abstract The importance of Blockchain and IoT technology have been highlighted in various fields. These are not unaccustomed words anymore in our lives. Although the technologies are in the infancy step and are still many remaining technical challenges, there is no doubt that it will be one of the major parts of the future Internet. The efficiency and security of data transmission scheme have always been major issues in the legacy Internet, and a data transmission scheme for the future Internet, including 5G and IoT environment should also provide and support these issues. Consequently, we propose a new data transmission scheme… More >

  • Open Access

    ARTICLE

    DPIF: A Framework for Distinguishing Unintentional Quality Problems From Potential Shilling Attacks

    Mohan Li1, Yanbin Sun1, *, Shen Su1, Zhihong Tian1, Yuhang Wang1, *, Xianzhi Wang2

    CMC-Computers, Materials & Continua, Vol.59, No.1, pp. 331-344, 2019, DOI:10.32604/cmc.2019.05379

    Abstract Maliciously manufactured user profiles are often generated in batch for shilling attacks. These profiles may bring in a lot of quality problems but not worthy to be repaired. Since repairing data always be expensive, we need to scrutinize the data and pick out the data that really deserves to be repaired. In this paper, we focus on how to distinguish the unintentional data quality problems from the batch generated fake users for shilling attacks. A two-steps framework named DPIF is proposed for the distinguishment. Based on the framework, the metrics of homology and suspicious degree are proposed. The homology can… More >

  • Open Access

    ARTICLE

    Hybrid Simulation and Observation of Human Vertebral Endplate Morphology

    É. Budyn1, A. Bilagi2, V. Subramanian3, A.A. Espinoza Orías4, N. Inoue4

    CMES-Computer Modeling in Engineering & Sciences, Vol.98, No.3, pp. 341-374, 2014, DOI:10.32604/cmes.2014.098.341

    Abstract Focal damage such as cartilaginous defects, erosions, micro-fractures, Schmorl nodes and thinning in the human vertebral endplate are thought to contribute to intervertebral disc degeneration by compromising the nutrition transport between the vertebral bone marrow and the disc nucleus pulposus. However, microfractures in the endplate are currently not detectable by conventional clinical radiographic methods. Nonetheless high quality visualisation of the human endplate is possible by means of advanced light microscopy and appropriate staining. The objective of this study focuses on efficient and inexpensive multi-scale protocols to prepare the surfaces of human endplate specimens for morphometric characterisations at the tissue and… More >

  • Open Access

    ARTICLE

    Comparative Study of the Water Response to External Force at Nanoscale and Mesoscale

    H.T. Liu1,2, Z. Chen2, S. Jiang2, Y. Gan3, M.B. Liu4, J.Z. Chang1, Z.H. Tong1

    CMES-Computer Modeling in Engineering & Sciences, Vol.95, No.4, pp. 303-315, 2013, DOI:10.3970/cmes.2013.095.303

    Abstract Dissipative particle dynamics (DPD) and molecular dynamics (MD) are both Lagrangian particle-based methods with similar equations except that the DPD specification for the force definition on the particles is the result of coarsegraining, and these two methods usually get the similar results in some specific cases. However, there are still some unknown differences between them. Considering the water response to external force, a comparative study of DPD and MD is conducted in this paper, which provides a better understanding on their relation, and a potential way to effectively bridge nanoscale and mesoscale simulation procedures. It is shown that there is… More >

  • Open Access

    ARTICLE

    Computational Characterization and Evaluation of Deformation Behavior of Spherulite of High Density Polyethylene in Mesoscale Domain

    Y. Tomita 1, M. Uchida 1

    CMES-Computer Modeling in Engineering & Sciences, Vol.10, No.3, pp. 239-248, 2005, DOI:10.3970/cmes.2005.010.239

    Abstract In this study, we clarified the micro- to mesoscopic deformation behavior of a semicrystalline polymer by employing a large-deformation finite element homogenization method. The crystalline plasticity theory with a penalty method for the inextensibility of the chain direction and the nonaffine molecular chain network theory were applied for the representation of the deformation behavior of the crystalline and amorphous phases, respectively, in the composite microstructure of the semicrystalline polymer. The 3D structure of lamellae in the spherulite of high-density polyethylene was modeled, and the tensile and compressive deformation behaviors were investigated. A series of computational simulations clarified the difference in… More >

  • Open Access

    ARTICLE

    A Highly Effective DPA Attack Method Based on Genetic Algorithm

    Shuaiwei Zhang1, Xiaoyuan Yang1,*, Weidong Zhong1, Yujuan Sun2

    CMC-Computers, Materials & Continua, Vol.56, No.2, pp. 325-338, 2018, DOI:10.3970/cmc.2018.03611

    Abstract As one of the typical method for side channel attack, DPA has become a serious trouble for the security of encryption algorithm implementation. The potential capability of DPA attack induces researchers making a lot of efforts in this area, which significantly improved the attack efficiency of DPA. However, most of these efforts were made based on the hypothesis that the gathered power consumption data from the target device were stable and low noise. If large deviation happens in part of the power consumption data sample, the efficiency of DPA attack will be reduced rapidly. In this work, a highly efficient… More >

  • Open Access

    ARTICLE

    Time-Dependent J-Integral Solution for Semi-elliptical Surface Crack in HDPE

    M. Bendouba1, A. Djebli1, A. Aid1, N. Benseddiq2, M. Benguediab3

    CMC-Computers, Materials & Continua, Vol.45, No.3, pp. 163-186, 2015, DOI:10.3970/cmc.2015.045.163

    Abstract This work focuses on a linear elastic analysis by the finite element method and the development of a shape function, commonly known as geometrical correction factor, for the case of semi-elliptical crack in a cylindrical rod. We used the same shape function to analyze the behavior of the rod in the case of a viscoelastic medium materialized by a polymeric material such as HDPE. A linear viscoelastic model calibrated from a relaxation test was developed and implemented in Abaqus. Results showed a relatively good performance, compared with finite element method. More >

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