BOWEN PENG¹, YUN GE¹, GANG YIN^2,3,*

BIOCELL, Vol.47, No.7, pp. 1519-1535, 2023, DOI:10.32604/biocell.2023.027026

Abstract Background: Tanshinone IIA, one of the main ingredients of Danshen, is used to treat hepatocellular carcinoma (HCC). However, potential targets of the molecule in the therapy of HCC are unknown. Methods: In this study, we collected the tanshinone IIA targets from public databases for investigation. We screened differentially expressed genes (DEGs) across HCC and normal tissues using mRNA expression profiles from The Cancer Genome Atlas (TCGA). Univariate Cox regression analysis and least absolute shrinkage and selection operator (LASSO) Cox regression models were used to identify and construct the prognostic gene signature. Results: Finally, we discovered common genes across tanshinone IIA… More >

Shiqi Luo^1,3, Wenbo Chen^2,3,*, Lei He⁴, Qiongbing Xiong^1,3

Phyton-International Journal of Experimental Botany, Vol.92, No.2, pp. 455-470, 2023, DOI:10.32604/phyton.2022.022466

Abstract As one of the basic theories of biodiversity conservation, island biogeography has been widely accepted in the past decades. Originally, island biogeography was put forward and applied in oceanic environments. But later on, it was found out that the application was not only limited to oceanic islands, but also in terrestrial environments with relatively isolated conditions. In terms of biodiversity level, island biogeography generally focuses on a small scale, such as species diversity and genetic diversity. The studies of biodiversity on a large-scale based on island biogeography, such as ecosystem and landscape scales, were seldomly conducted. Taking Poyang Lake, the… More >

Ahmed Abdulhakim Al-Absi¹, Dae-Ki Kang^2,*, Mohammed Abdulhakim Al-Absi³

CMC-Computers, Materials & Continua, Vol.74, No.1, pp. 671-691, 2023, DOI:10.32604/cmc.2023.030262

Abstract Sentiment analysis (AS) is one of the basic research directions in natural language processing (NLP), it is widely adopted for news, product review, and politics. Aspect-based sentiment analysis (ABSA) aims at identifying the sentiment polarity of a given target context, previous existing model of sentiment analysis possesses the issue of the insufficient exaction of features which results in low accuracy. Hence this research work develops a deep-semantic and contextual knowledge networks (DSCNet). DSCNet tends to exploit the semantic and contextual knowledge to understand the context and enhance the accuracy based on given aspects. At first temporal relationships are established then… More >

Hyoe Hatakeyama^1,*, Tatsuko Hatakeyama²

Journal of Renewable Materials, Vol.1, No.2, pp. 113-123, 2013, DOI:10.7569/JRM.2012.634111

Abstract Lignin and saccharides are two major components of plants. Huge amounts of plant residues are obtained as by-products of large-scale industries, such as pulp and paper, bio-fuel and the food industry. In this paper, preparation of polyurethane (PU) foam directly from various kinds of industrial lignin and molasses, which have scarcely been utilized, is summarized based on our results obtained by recent investigation. A onestep reaction using hydroxyl groups of plant materials as an active site makes it possible to produce a wide variety of PU, such as foams, sheets, gels and composite matrix. In this paper, PU foams receive… More >

Jaša Saražin¹, Ida Poljanšek¹, Antonio Pizzi², Milan Šernek^1,*

Journal of Renewable Materials, Vol.10, No.8, pp. 2117-2131, 2022, DOI:10.32604/jrm.2022.019602

Abstract The curing process of two biobased adhesives: pine tanninhexamine (TH) and organosolv lignin non-isocyanate polyurethane (NIPU), suitable for interior nonstructural use, were compared with commercial urea-formaldehyde (UF) adhesive. Changes in chemical structure before and after the curing process were observed with Fouriertransform infrared spectroscopy (FTIR). The process of adhesive curing was monitored with differential scanning calorimetry (DSC) and the automated bonding evaluation system (ABES). Both DSC and ABES measurements confirmed UF as the fastest and NIPU as the slowest curing adhesive observed. Taking into account the ABES results, the optimal pressing parameters for the TH adhesive would be 4 min… More >

HONGYANG LI^1,2, CHAN WANG⁴, SHIWEI LIU¹, YONGLONG GUO^1,3,4,*, JIANSU CHEN^1,3,4,*

BIOCELL, Vol.46, No.7, pp. 1705-1716, 2022, DOI:10.32604/biocell.2022.018442

Abstract Human adipose stem cells (hADSCs) are reliable sources for cell therapy. However, the clinical applications are limited by the decrease in activity during in vitro culture. We used a knockout serum replacement (KSR) medium, Eppendorf (EP) tube culture, and a simulated microgravity (SMG) culture system to establish hADSC spheroids. We found that hADSCs aggregated and formed spheroids in the KSR culture medium. The EP tube culture method revealed many biological cell characteristics, such as good cell viabilities, rough surfaces, polar growth, fusion phenomenon, and injectability. The findings show its advantages for hADSCs spherical cultures. When cultured in SMG, hADSC spheroids… More >

Emmanuel U. Opara^1,*, Oredola A. Soluade²

Journal of Cyber Security, Vol.3, No.3, pp. 167-176, 2021, DOI:10.32604/jcs.2021.019158

Abstract The ecosystem security platform described in this research is already impacting the threat spectrum in quantifiable ways. The global network has undergone a dramatic transformation over the course of 2020, with an unprecedented destabilization of events. Security breaches of all kinds are growing in complexity, sophistication, and impact. The bad actors are bypassing predictable security devices at will by breaching network systems at an escalating rate. This study will analyze these developments by creating awareness among security practitioners so they can be prepared to defend their enterprise systems. More >

Yanhong Li^*, Bing Li, Xinhui Fan, Ke Yang, Xin Wang

FDMP-Fluid Dynamics & Materials Processing, Vol.18, No.1, pp. 71-80, 2022, DOI:10.32604/fdmp.2022.017922

Abstract In this study a Cu₄₃Zr₄₈Al₉ bulk metallic glass prepared by the copper mold casting method is considered. In recent years, Cu-Zr-Al systems like this have enjoyed widespread attention due to their high strength, high hardness, high corrosion resistance and low cost. Here samples of this substance are studied using DSC (Differential scanning calorimetry) to determine the effect of different test conditions (heating rate, sample mass, sample specific surface area and sample crystal phase) on the characteristic thermodynamic temperature of the bulk metallic glass. Experimental results show that almost all of the five characteristic thermodynamic temperatures (T_g, T_x, T_p, T_m, T_l)… More >

Saeed AlQadhi¹, Javed Mallick^1,*, Swapan Talukdar², Ahmed Ali Bindajam³, Ahmed Ali A. Shohan³, Shahfahad⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.129, No.2, pp. 755-786, 2021, DOI:10.32604/cmes.2021.016640

Abstract Given that many cities in Saudi Arabia have been observing rapid urbanization since the 1990s, scarce studies on the spatial pattern of urban expansion in Saudi Arabia have been conducted. Therefore, the present study investigates the evidence of land use and land cover (LULC) dynamics and urban sprawl in Abha City of Saudi Arabia, which has been experiencing rapid urbanization, from the past to the future using novel and sophisticated methods. The SVM classifier was used in this study to classify the LULC maps for 1990, 2000, and 2018. The LULC dynamics between 1990–2000, 2000–2018, and 1990–2018 have been analyzed… More >

JIANFEI GAO¹, KANGNING XIONG^2,*, WEIJIE LI¹, WEI ZHOU³

BIOCELL, Vol.46, No.1, pp. 285-296, 2022, DOI:10.32604/biocell.2021.016253

Abstract Kadsura coccinea (Lem.) is a woody wine plant with a peculiar fruit enriched in important health-promoting compounds. The non-editable part of the fruit, i.e., the seed and peel, represents more than 60% of the fruit and is considered a biowaste. This significantly restricts the development of the K. coccinea fruit industry. Clarifying the metabolic components of the different fruit parts can help to improve the utilization rate and valorization of K. coccinea. Herein, we evaluated K. coccinea fruit peel, pulp, and seed using widely-targeted metabolomics and quantified a set of 736 bioactive compounds from 11 major metabolite classes. The most… More >