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  • Open Access

    ARTICLE

    An Intelligent Medical Expert System Using Temporal Fuzzy Rules and Neural Classifier

    Praveen Talari1,*, A. Suresh2, M. G. Kavitha3

    Intelligent Automation & Soft Computing, Vol.35, No.1, pp. 1053-1067, 2023, DOI:10.32604/iasc.2023.027024 - 06 June 2022

    Abstract As per World Health Organization report which was released in the year of 2019, Diabetes claimed the lives of approximately 1.5 million individuals globally in 2019 and around 450 million people are affected by diabetes all over the world. Hence it is inferred that diabetes is rampant across the world with the majority of the world population being affected by it. Among the diabetics, it can be observed that a large number of people had failed to identify their disease in the initial stage itself and hence the disease level moved from Type-1 to Type-2.… More >

  • Open Access

    ARTICLE

    Angiogenic Gene PTK2 is a Potential Biomarker of Gestational Diabetes Mellitus and is Significantly Associated with Breast Cancer Immune Infiltration

    Xuelian Du1,#, Hao Shi2,#, Haiyan Liu1, Linghua Zhou1, Anqun Xie1, Jufang Guo1,*

    Oncologie, Vol.24, No.4, pp. 769-787, 2022, DOI:10.32604/oncologie.2022.026248 - 31 December 2022

    Abstract Background: Gestational diabetes mellitus (GDM) affects the health of numerous women around the world. A recent study has shown that GDM is associated with an increased incidence of cancer. In this study, we aimed to explore the possible shared mechanisms and potential common therapeutic targets between GDM and cancer. Methods: The limma package was used to identify differentially expressed genes (DEGs) in GDM. The Cytoscape plugin cytoHubba was used to screen hub genes. The CIBERSORT algorithm was used to explore the correlation between hub genes and immunity. Cox regression analysis was used to assess the relationship… More >

  • Open Access

    ARTICLE

    Diabetes Prediction Using Derived Features and Ensembling of Boosting Classifiers

    R. Rajkamal1,*, Anitha Karthi2, Xiao-Zhi Gao3

    CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 2013-2033, 2022, DOI:10.32604/cmc.2022.027142 - 18 May 2022

    Abstract Diabetes is increasing commonly in people’s daily life and represents an extraordinary threat to human well-being. Machine Learning (ML) in the healthcare industry has recently made headlines. Several ML models are developed around different datasets for diabetic prediction. It is essential for ML models to predict diabetes accurately. Highly informative features of the dataset are vital to determine the capability factors of the model in the prediction of diabetes. Feature engineering (FE) is the way of taking forward in yielding highly informative features. Pima Indian Diabetes Dataset (PIDD) is used in this work, and the… More >

  • Open Access

    ARTICLE

    Dm-Health App: Diabetes Diagnosis Using Machine Learning with Smartphone

    Elias Hossain1, Mohammed Alshehri2, Sultan Almakdi2,*, Hanan Halawani2, Md. Mizanur Rahman3, Wahidur Rahman4, Sabila Al Jannat5, Nadim Kaysar6, Shishir Mia4

    CMC-Computers, Materials & Continua, Vol.72, No.1, pp. 1713-1746, 2022, DOI:10.32604/cmc.2022.024822 - 24 February 2022

    Abstract Diabetes Mellitus is one of the most severe diseases, and many studies have been conducted to anticipate diabetes. This research aimed to develop an intelligent mobile application based on machine learning to determine the diabetic, pre-diabetic, or non-diabetic without the assistance of any physician or medical tests. This study's methodology was classified into two the Diabetes Prediction Approach and the Proposed System Architecture Design. The Diabetes Prediction Approach uses a novel approach, Light Gradient Boosting Machine (LightGBM), to ensure a faster diagnosis. The Proposed System Architecture Design has been combined into seven modules; the Answering… More >

  • Open Access

    ARTICLE

    Detection of Diabetic Retinopathy Using Custom CNN to Segment the Lesions

    Saleh Albahli1,2,*, Ghulam Nabi Ahmad Hassan Yar3

    Intelligent Automation & Soft Computing, Vol.33, No.2, pp. 837-853, 2022, DOI:10.32604/iasc.2022.024427 - 08 February 2022

    Abstract Diabetic retinopathy is an eye deficiency that affects the retina as a result of the patient having Diabetes Mellitus caused by high sugar levels. This condition causes the blood vessels that nourish the retina to swell and become distorted and eventually become blocked. In recent times, images have played a vital role in using convolutional neural networks to automatically detect medical conditions, retinopathy takes this to another level because there is need not for just a system that could determine is a patient has retinopathy, but also a system that could tell the severity of… More >

  • Open Access

    ARTICLE

    Analysis of specific lipid metabolites in cord blood of patients with gestational diabetes mellitus

    YANQIU LI#,*, CHENJUN HAO#, WEIYI CHEN, QINGJU MENG

    BIOCELL, Vol.46, No.6, pp. 1565-1573, 2022, DOI:10.32604/biocell.2022.018347 - 07 February 2022

    Abstract This work aimed to clarify the interaction between the fetus and pregnant patients with gestational diabetes mellitus (GDM), the lipid metabolomics analysis of the fetal umbilical cord blood of GDM patients and normal pregnant women were performed to screen out the specific lipid metabolites for pathogenesis of GDM. From 2019–2020, 21 patients with GDM and 22 normal pregnant women were enrolled in Hexian Memorial Hospital, Panyu District, Guangzhou. The general information such as weight, height, age, body mass index (BMI) before pregnancy were analyzed. Non-targeted metabonomic detection and analysis were performed in umbilical cord plasma… More >

  • Open Access

    ARTICLE

    A Hybrid Meta-Classifier of Fuzzy Clustering and Logistic Regression for Diabetes Prediction

    Altyeb Altaher Taha*, Sharaf Jameel Malebary

    CMC-Computers, Materials & Continua, Vol.71, No.3, pp. 6089-6105, 2022, DOI:10.32604/cmc.2022.023848 - 14 January 2022

    Abstract Diabetes is a chronic health condition that impairs the body's ability to convert food to energy, recognized by persistently high levels of blood glucose. Undiagnosed diabetes can cause many complications, including retinopathy, nephropathy, neuropathy, and other vascular disorders. Machine learning methods can be very useful for disease identification, prediction, and treatment. This paper proposes a new ensemble learning approach for type 2 diabetes prediction based on a hybrid meta-classifier of fuzzy clustering and logistic regression. The proposed approach consists of two levels. First, a base-learner comprising six machine learning algorithms is utilized for predicting diabetes.… More >

  • Open Access

    ARTICLE

    To Control Diabetes Using Machine Learning Algorithm and Calorie Measurement Technique

    T. Viveka1,*, C. Christopher Columbus2, N. Senthil Velmurugan3

    Intelligent Automation & Soft Computing, Vol.33, No.1, pp. 535-547, 2022, DOI:10.32604/iasc.2022.022976 - 05 January 2022

    Abstract Because of the increasing workload, people are having several clinical examinations to determine their health status, resulting in limited time. Here, we present a healthful consuming device based on rule mining that can modify your parameter dependency and recommend the varieties of meals that will boost your fitness and assist you to avoid the types of meals that increase your risk for sicknesses. Using the meals database, the data mining technique is useful for gathering meal energy from breakfast, after breakfast, lunch, after lunch, dinner, after dinner, and bedtime for ninety days. The purpose of… More >

  • Open Access

    ARTICLE

    Quantitative Evaluation of Mental-Health in Type-2 Diabetes Patients Through Computational Model

    Fawaz Alassery1, Ahmed Alzahrani2, Asif Irshad Khan2, Ashi Khan3,*, Mohd Nadeem4, Md Tarique Jamal Ansari4

    Intelligent Automation & Soft Computing, Vol.32, No.3, pp. 1701-1715, 2022, DOI:10.32604/iasc.2022.023314 - 09 December 2021

    Abstract A large number of people live in diabetes worldwide. Type-2 Diabetes (D2) accounts for 92% of patients with D2 and puts a huge burden on the healthcare industry. This multi-criterion medical research is based on the data collected from the hospitals of Uttar Pradesh, India. In recent times there is a need for a web-based electronic system to determine the impact of mental health in D2 patients. This study will examine the impact assessment in D2 patients. This paper used the integrated methodology of Fuzzy Analytic Hierarchy (FAHP) and Fuzzy Technique for Order Performance by… More >

  • Open Access

    ARTICLE

    Anti-inflammatory and antioxidant potential capacities of AD-MSCs and BM-MSCs in suppressing pancreatic β-cells auto-immunity and apoptosis in rats with T1DM induced model

    SHADY G. EL-SAWAH1,*, FAYEZ ALTHOBAITI2, HANAN M. RASHWAN1, ADIL ALDHAHRANI3, MARWA A. ABDEL-DAYEM4, EMAN FAYAD2, REHAB M. AMEN5, EL SHAIMAA SHABANA6, EHAB I. EL-HALLOUS7

    BIOCELL, Vol.46, No.3, pp. 745-757, 2022, DOI:10.32604/biocell.2022.017853 - 18 November 2021

    Abstract Since Type 1 diabetes (T1DM) occurs when β-cells mass is reduced to less than 20% of the normal level due to autoimmune destruction of cells resulting in the inability to secrete insulin, preservation or replenishment of the functional β-cells mass has become a major therapeutic focus for this diabetic type treatment. Thus, this 4-week work plan was designed to determine which mesenchymal stem cells (MSCs) type is more appropriate to alleviate pancreatic hazards resulting from diabetes induction; via tracking a comparative study between MSCs derived from adipose tissue (AD-MSCs) and from bone marrow (BM-MSCs) in… More >

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