Huihui Shi^1,#, Lei Chen^2,#, Juan Huang^3,#, Xuejing Lin², Lei Huang⁴, Min Tang⁴, Kai Lu^5,*, Wenchao Wang^4,*, Maoling Zhu^1,§,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.068737 - 30 December 2025

Abstract Background: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. This study aimed to identify key genes involved in HCC development and elucidate their molecular mechanisms, with a particular focus on mitochondrial function and apoptosis. Methods: Differential expression analyses were performed across three datasets—The Cancer Genome Atlas (TCGA)-Liver Hepatocellular Carcinoma (LIHC), GSE36076, and GSE95698—to identify overlapping differentially expressed genes (DEGs). A prognostic risk model was then constructed. Cysteine/serine-rich nuclear protein 1 (CSRNP1) expression levels in HCC cell lines were assessed via western blot (WB) and quantitative reverse transcription polymerase chain reaction (qRT-PCR).… More > Graphic Abstract

Sk. A. Shezan^*

Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.073418 - 27 December 2025

Abstract Modern power systems increasingly depend on interconnected microgrids to enhance reliability and renewable energy utilization. However, the high penetration of intermittent renewable sources often causes frequency deviations, voltage fluctuations, and poor reactive power coordination, posing serious challenges to grid stability. Conventional Interconnection Flow Controllers (IFCs) primarily regulate active power flow and fail to effectively handle dynamic frequency variations or reactive power sharing in multi-microgrid networks. To overcome these limitations, this study proposes an enhanced Interconnection Flow Controller (e-IFC) that integrates frequency response balancing and an Interconnection Reactive Power Flow Controller (IRFC) within a unified adaptive… More >

Nan Qin¹, Shaofeng Ning^2,*, Zihan Zhao^1,2, Yu Luo¹, Bo Chen¹, Xiaoxu Liu¹, Yongming He²

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.12, pp. 2997-3009, 2025, DOI:10.32604/fdmp.2025.074456 - 31 December 2025

Abstract Balancing CO₂ emission reduction with enhanced gas recovery in carbonate reservoirs remains a key challenge in subsurface energy engineering. This study focuses on the Maokou Formation gas reservoir in the Wolonghe Gas Field, Sichuan Basin, and employs a mechanistic model integrated with numerical simulations that couple CO₂–water–rock geochemical interactions to systematically explore the principal engineering and chemical factors governing Carbon Capture, Utilization, and Storage–Enhanced Gas Recovery (CCUS–EGR). The analysis reveals that both the injection–production ratio and gas injection rate exhibit optimal ranges. Maximum gas output under single-parameter variation occurs at an injection–production ratio of 0.7 and… More >

Dong Hu^1,2, Lingxing Hu³, Facheng Qiu^3,*

Frontiers in Heat and Mass Transfer, Vol.23, No.6, pp. 1865-1882, 2025, DOI:10.32604/fhmt.2025.073409 - 31 December 2025

Abstract With the acceleration of industrialization and urbanization, ammonia nitrogen pollution in water bodies has become increasingly severe, making the development of efficient and low-consumption wastewater treatment technologies highly significant. This study employs three-dimensional computational fluid dynamics (CFD) to investigate the cavitation mechanisms and flow field characteristics in a novel jet impingement-negative pressure ammonia removal reactor. The simulation, validated by experimental pressure data with a high degree of consistency, utilizes the Mixture model, the Realizable k-ε turbulence model, and the Schnerr-Sauer cavitation model. The results demonstrate that the flow velocity undergoes a substantial acceleration within the… More > Graphic Abstract

Ling Li^1,#, Ninghui Xu^1,#, Wenjing Wang^2,*, Jianfen Ying^1,*

Journal of Psychology in Africa, Vol.35, No.6, pp. 833-842, 2025, DOI:10.32604/jpa.2025.071557 - 30 December 2025

Abstract This study explores the role of teachers’ professional identity (TPI) on employee learning engagement (LE), with mediation by basic needs satisfaction (BNS). Participants were 255 Chinese pre-service teachers (191 females = 74.9%, 16 freshmen = 6.2%, 135 sophomores = 52.9%, 35 juniors = 12.5%, 72 seniors = 28.2%). They completed surveys on the “QuestionStar” online survey platform and 12 of the teachers completed interviews for sharing their personal insights. The results of Structural Equation Modeling (SEM) indicated that teachers’ professional identity significantly predicted both learning engagement and basic needs satisfaction, with basic needs satisfaction partially More >

YANG-YANG SHUAI^1,2, PEI-PEI WANG¹, HAI-JUN ZHANG², HUI AO^1,*, WEI PENG¹, HONG ZHANG^1,2,*

BIOCELL, Vol.49, No.12, pp. 2299-2333, 2025, DOI:10.32604/biocell.2025.071569 - 24 December 2025

Abstract Breast cancer ranks first among cancer-related fatalities and is the most frequent cancer in women globally. ROS plays an important role in controlling the occurrence and progression of breast cancer. Increasing reports suggest that natural products and their derivatives are beneficial for the management of breast cancer via the regulation of reactive oxygen species (ROS). A summary of the known patterns of natural products that modulate ROS against breast cancer will contribute to the discovery of more natural medicines for clinical applications and the development of new drugs. In this review, the pharmacological effects of More >

Asgar Ali^1,*, Nayan Sardar², Poly Karmakar³, Sanatan Das⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 3563-3626, 2025, DOI:10.32604/cmes.2025.074082 - 23 December 2025

Abstract Hybrid nanofluids have gained significant attention for their superior thermal and rheological characteristics, offering immense potential in energy conversion, biomedical transport, and electromagnetic flow control systems. Understanding their dynamic behavior under coupled magnetic, rotational, and reactive effects is crucial for the development of efficient thermal management technologies. This study develops a neuro-fuzzy computational framework to examine the dynamics of a reactive Cu–TiO₂–H₂O hybrid nanofluid flowing through a squarely elevated Riga tunnel. The governing model incorporates Hall and ion-slip effects, thermal radiation, and first-order chemical reactions under ramped thermo-solutal boundary conditions and rotational electromagnetic forces. Closed-form analytical… More >

Sena Yıldız¹, Nurhan Keskin^2,*, Birhan Kunter³, Harlene Hatterman-Valenti⁴, Ozkan Kaya^4,5,*

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3471-3492, 2025, DOI:10.32604/phyton.2025.073180 - 01 December 2025

Abstract Climate change-driven environmental stresses, particularly ultraviolet-B (UV-B) radiation, pose severe threats to grapevine (Vitis vinifera L.) productivity and physiological stability. This study investigated the protective role of melatonin in in vitro plantlets of two grapevine cultivars, ‘Merlot’ and ‘Erciş’, subjected to low (≈8.25 μW cm⁻², 16 h) and high (≈33 μW cm⁻², 4 h) UV-B exposure. Significant cultivar-specific responses were observed (p < 0.001). The ‘Erciş’ cultivar exhibited higher oxidative stress, with malondialdehyde (MDA) levels reaching 24.30 mmol g⁻¹ FW in control plants compared with 14.91 ± 0.25 mmol g⁻¹ FW in ‘Merlot’. Melatonin provided dose-dependent mitigation, reducing MDA to… More >

Burak Canpolat^1,*, Göktuğ Norman², Cemal Gündoğdu², Şakir Tüfekçi², Yalın Aygün², Taylan Akbuğa³

International Journal of Mental Health Promotion, Vol.27, No.11, pp. 1781-1795, 2025, DOI:10.32604/ijmhp.2025.069852 - 28 November 2025

Abstract Objectives: This study examines the effectiveness of an eight-week game-based physical activity program designed to reduce post-traumatic stress levels in children affected by the Kahramanmaraş-centered earthquakes that occurred in Turkey on 06 February 2023. Following the earthquake, millions of children experienced significant changes in their education and living conditions, adversely affecting their psychological health. Methods: The therapeutic effects of physical activity on post-traumatic stress disorder (PTSD) are frequently emphasized in the literature, and this study specifically focuses on the impact of game-based exercises. The research employed an experimental design, involving 80 earthquake-affected children aged 10 to… More >

Huanfang Wang^1,*, Xinyi Li¹, Fangfang Zhao², Ximeng Cui³, Weijian Li⁴

International Journal of Mental Health Promotion, Vol.27, No.11, pp. 1813-1827, 2025, DOI:10.32604/ijmhp.2025.069623 - 28 November 2025

Abstract Background: In China, the policy of rotating teachers between urban and rural schools has been implemented to reduce educational disparities and ensure equitable access to quality education. These teachers face unique professional and emotional challenges during the rotation process, making their emotional labor a critical factor influencing their job performance. This study aimed to explore the relationship between rotating teachers’ emotional labor strategies and job performance. Methods: This study conducted a cross-sectional survey among 577 rotating teachers selected through stratified random sampling from primary and secondary schools in mainland China. Date were collected using the Teacher… More >