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  • Open Access

    ARTICLE

    Computational Algorithms for the Analysis of Cancer Virotherapy Model

    Ali Raza1,2,*, Dumitru Baleanu3,4, Muhammad Rafiq5, Syed Zaheer Abbas6, Abubakar Siddique6, Umer Javed8, Mehvish Naz7, Arooj Fatima6, Tayyba Munawar6, Hira Batool6, Zaighum Nazir6

    CMC-Computers, Materials & Continua, Vol.71, No.2, pp. 3621-3634, 2022, DOI:10.32604/cmc.2022.023286 - 07 December 2021

    Abstract Cancer is a common term for many diseases that can affect any part of the body. In 2020, ten million people will die due to cancer. A worldwide leading cause of death is cancer by the World Health Organization (WHO) report. Interaction of cancer cells, viral therapy, and immune response are identified in this model. Mathematical and computational modeling is an effective tool to predict the dynamics of cancer virotherapy. The cell population is categorized into three parts like uninfected cells (x), infected cells (y), virus-free cells (v), and immune cells (z). The modeling of More >

  • Open Access

    ARTICLE

    Analysis of Pneumonia Model via Efficient Computing Techniques

    Kamaledin Abodayeh1, Ali Raza2,3,*, Muhammad Rafiq4, Muhammad Shoaib Arif5, Muhammad Naveed5, Zunir Zeb3, Syed Zaheer Abbas3, Kiran Shahzadi3, Sana Sarwar3, Qasim Naveed3, Badar Ul Zaman3, Muhammad Mohsin6

    CMC-Computers, Materials & Continua, Vol.70, No.3, pp. 6073-6088, 2022, DOI:10.32604/cmc.2022.020732 - 11 October 2021

    Abstract Pneumonia is a highly transmissible disease in children. According to the World Health Organization (WHO), the most affected regions include south Asia and sub-Saharan Africa. Worldwide, 15% of pediatric deaths can be attributed to pneumonia. Computing techniques have a significant role in science, engineering, and many other fields. In this study, we focused on the efficiency of numerical techniques via computer programs. We studied the dynamics of the pneumonia-like infections of epidemic models using numerical techniques. We discuss two types of analysis: dynamical and numerical. The dynamical analysis included positivity, boundedness, local stability, reproduction number, More >

  • Open Access

    ARTICLE

    Treatment of Polio Delayed Epidemic Model via Computer Simulations

    Muhammad Naveed1,*, Dumitru Baleanu2,3, Ali Raza4, Muhammad Rafiq5, Atif Hassan Soori1

    CMC-Computers, Materials & Continua, Vol.70, No.2, pp. 3415-3431, 2022, DOI:10.32604/cmc.2022.020112 - 27 September 2021

    Abstract Through the study, the nonlinear delayed modelling has vital significance in the different field of allied sciences like computational biology, computational chemistry, computational physics, computational economics and many more. Polio is a contagious viral illness that in its most severe form causes nerve injury leading to paralysis, difficulty breathing and sometimes death. In recent years, developing regions like Asia, Africa and sub-continents facing a dreadful situation of poliovirus. That is the reason we focus on the treatment of the polio epidemic model with different delay strategies in this article. Polio delayed epidemic model is categorized More >

  • Open Access

    ARTICLE

    Design of Computer Methods for the Solution of Cervical Cancer Epidemic Model

    Ali Raza1, Muhammad Rafiq2, Dalal Alrowaili3, Nauman Ahmed4, Ilyas Khan5,*, Kottakkaran Sooppy Nisar6, Muhammad Mohsin7

    CMC-Computers, Materials & Continua, Vol.70, No.1, pp. 1649-1666, 2022, DOI:10.32604/cmc.2022.019148 - 07 September 2021

    Abstract Nonlinear modelling has a significant role in different disciplines of sciences such as behavioral, social, physical and biological sciences. The structural properties are also needed for such types of disciplines, as dynamical consistency, positivity and boundedness are the major requirements of the models in these fields. One more thing, this type of nonlinear model has no explicit solutions. For the sake of comparison its computation will be done by using different computational techniques. Regrettably, the aforementioned structural properties have not been restored in the existing computational techniques in literature. Therefore, the construction of structural preserving… More >

  • Open Access

    ARTICLE

    Dynamical Transmission of Coronavirus Model with Analysis and Simulation

    Muhammad Farman1, Ali Akgül2,*, Aqeel Ahmad1, Dumitru Baleanu3,4,5, Muhammad Umer Saleem6

    CMES-Computer Modeling in Engineering & Sciences, Vol.127, No.2, pp. 753-769, 2021, DOI:10.32604/cmes.2021.014882 - 19 April 2021

    Abstract COVID-19 acts as a serious challenge to the whole world. Epidemiological data of COVID-19 is collected through media and web sources to analyze and investigate a system of nonlinear ordinary differential equation to understand the outbreaks of this epidemic disease. We analyze the diseases free and endemic equilibrium point including stability of the model. The certain threshold value of the basic reproduction number R0 is found to observe whether population is in disease free state or endemic state. Moreover, the epidemic peak has been obtained and we expect a considerable number of cases. Finally, some numerical More >

  • Open Access

    ARTICLE

    New Fuzzy Fractional Epidemic Model Involving Death Population

    Prasantha Bharathi Dhandapani1, Dumitru Baleanu2,3,4,*, Jayakumar Thippan1, Vinoth Sivakumar1

    Computer Systems Science and Engineering, Vol.37, No.3, pp. 331-346, 2021, DOI:10.32604/csse.2021.015619 - 08 March 2021

    Abstract In this research, we propose a new change in classical epidemic models by including the change in the rate of death in the overall population. The existing models like Susceptible-Infected-Recovered (SIR) and Susceptible-Infected-Recovered-Susceptible (SIRS) include the death rate as one of the parameters to estimate the change in susceptible, infected and recovered populations. Actually, because of the deficiencies in immunity, even the ordinary flu could cause death. If people’s disease resistance is strong, then serious diseases may not result in mortalities. The classical model always assumes a closed system where there is no new birth… More >

  • Open Access

    ARTICLE

    Optimality of Solution with Numerical Investigation for Coronavirus Epidemic Model

    Naveed Shahid1,2, Dumitru Baleanu3,4,5, Nauman Ahmed1,2, Tahira Sumbal Shaikh6, Ali Raza7,*, Muhammad Sajid Iqbal1, Muhammad Rafiq8, Muhammad Aziz-ur Rehman2

    CMC-Computers, Materials & Continua, Vol.67, No.2, pp. 1713-1728, 2021, DOI:10.32604/cmc.2021.014191 - 05 February 2021

    Abstract The novel coronavirus disease, coined as COVID-19, is a murderous and infectious disease initiated from Wuhan, China. This killer disease has taken a large number of lives around the world and its dynamics could not be controlled so far. In this article, the spatio-temporal compartmental epidemic model of the novel disease with advection and diffusion process is projected and analyzed. To counteract these types of diseases or restrict their spread, mankind depends upon mathematical modeling and medicine to reduce, alleviate, and anticipate the behavior of disease dynamics. The existence and uniqueness of the solution for… More >

  • Open Access

    ARTICLE

    Numerical Study of Computer Virus Reaction Diffusion Epidemic Model

    Umbreen Fatima1, Dumitru Baleanu2,3,4, Nauman Ahmed5,8, Shumaila Azam5, Ali Raza6,*, Muhammad Rafiq7, Muhammad Aziz-ur Rehman8

    CMC-Computers, Materials & Continua, Vol.66, No.3, pp. 3183-3194, 2021, DOI:10.32604/cmc.2021.012666 - 28 December 2020

    Abstract Reaction–diffusion systems are mathematical models which link to several physical phenomena. The most common is the change in space and time of the meditation of one or more materials. Reaction–diffusion modeling is a substantial role in the modeling of computer propagation like infectious diseases. We investigated the transmission dynamics of the computer virus in which connected to each other through network globally. The current study devoted to the structure-preserving analysis of the computer propagation model. This manuscript is devoted to finding the numerical investigation of the reaction–diffusion computer virus epidemic model with the help of a More >

  • Open Access

    ARTICLE

    A Structure Preserving Numerical Method for Solution of Stochastic Epidemic Model of Smoking Dynamics

    Ali Raza1, Muhammad Rafiq2, Nauman Ahmed3, Ilyas Khan4, *, Kottakkaran Sooppy Nisar5, Zafar Iqbal3

    CMC-Computers, Materials & Continua, Vol.65, No.1, pp. 263-278, 2020, DOI:10.32604/cmc.2020.011289 - 23 July 2020

    Abstract In this manuscript, we consider a stochastic smoking epidemic model from behavioural sciences. Also, we develop a structure preserving numerical method to describe the dynamics of stochastic smoking epidemic model in a human population. The structural properties of a physical system include positivity, boundedness and dynamical consistency. These properties play a vital role in non-linear dynamics. The solution for nonlinear stochastic models necessitates the conservation of these properties. Unfortunately, the aforementioned properties of the model have not been restored in the existing stochastic methods. Therefore, it is essential to construct a structure preserving numerical method More >

  • Open Access

    ARTICLE

    Dynamical Behavior and Sensitivity Analysis of a Delayed Coronavirus Epidemic Model

    Muhammad Naveed1, *, Dumitru Baleanu2, 3, 4, Muhammad Rafiq5, Ali Raza6, Atif Hassan Soori1, Nauman Ahmed7

    CMC-Computers, Materials & Continua, Vol.65, No.1, pp. 225-241, 2020, DOI:10.32604/cmc.2020.011534 - 23 July 2020

    Abstract Mathematical delay modelling has a significant role in the different disciplines such as behavioural, social, physical, biological engineering, and bio-mathematical sciences. The present work describes mathematical formulation for the transmission mechanism of a novel coronavirus (COVID-19). Due to the unavailability of vaccines for the coronavirus worldwide, delay factors such as social distance, quarantine, travel restrictions, extended holidays, hospitalization, and isolation have contributed to controlling the coronavirus epidemic. We have analysed the reproduction number and its sensitivity to parameters. If, More >

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