Nameer Baht^1,*, Enrique Domínguez^1,2,*

CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 4441-4455, 2025, DOI:10.32604/cmc.2025.069528 - 23 October 2025

Abstract Coffee is an important agricultural commodity, and its production is threatened by various diseases. It is also a source of concern for coffee-exporting countries, which is causing them to rethink their strategies for the future. Maintaining crop production requires early diagnosis. Notably, Coffee Leaf Miner (CLM) Machine learning (ML) offers promising tools for automated disease detection. Early detection of CLM is crucial for minimising yield losses. However, this study explores the effectiveness of using Convolutional Neural Networks (CNNs) with transfer learning algorithms ResNet50, DenseNet121, MobileNet, Inception, and hybrid VGG19 for classifying coffee leaf images as… More >

Luyao Jiang^1,#, Longsheng Fu^2,#, Shaofeng Xiong^2,3, Guosheng Cao⁴, Yanqin Mei^2,3, Yaoqi Wu², Jin Chen^1,*, Yanni LV^2,5,6,*

BIOCELL, Vol.49, No.9, pp. 1749-1769, 2025, DOI:10.32604/biocell.2025.068507 - 25 September 2025

Abstract Background: After ischemic stroke, neutrophils hyperactivate, increasing in number and worsening inflammation, causing neural damage. Prior scRNA-seq showed Lrg1 modulates cells subsentence to cerebral ischemia-reperfusion injury, but its mechanism in regulating neutrophil accumulation/differentiation post-injury is unclear. Methods: Lrg1 knockout impact on neutrophil accumulation was assessed via immunofluorescence and western blot. Three-dimensional reconstruction of immunofluorescent staining analyzed cell-cell interactions among neutrophils and microglia. scRNA-seq of WT and Lrg1^-/- mice from GSE245386 and GSE279462 was conducted. Each group conducted oxidative phosphorylation scoring via Gene Set Enrichment Analysis (GSEA), while Metascape was employed to perform GO and KEGG enrichment… More > Graphic Abstract

Caiping Huang^*, Hui Li, Zihang Yu

Structural Durability & Health Monitoring, Vol.19, No.5, pp. 1287-1304, 2025, DOI:10.32604/sdhm.2025.065930 - 05 September 2025

Abstract Semantic segmentation of concrete bridge defect images frequently encounters challenges due to insufficient precision and the limited computational capabilities of mobile devices, thereby considerably affecting the reliability of bridge defect monitoring and health assessment. To tackle these issues, a concrete defects dataset (including spalling, crack, and exposed steel rebar) was curated and multiple semantic segmentation models were developed. In these models, a deep convolutional network or a lightweight convolutional network were employed as the backbone feature extraction networks, with different loss functions configured and various attention mechanism modules introduced for conducting multi-angle comparative research. The… More >

Smita Khairnar^1,2, Shilpa Gite^1,3,*, Biswajeet Pradhan^4,*, Sudeep D. Thepade^2,5, Abdullah Alamri⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.3, pp. 3677-3707, 2025, DOI:10.32604/cmes.2025.058855 - 30 June 2025

Abstract Face liveness detection is essential for securing biometric authentication systems against spoofing attacks, including printed photos, replay videos, and 3D masks. This study systematically evaluates pre-trained CNN models— DenseNet201, VGG16, InceptionV3, ResNet50, VGG19, MobileNetV2, Xception, and InceptionResNetV2—leveraging transfer learning and fine-tuning to enhance liveness detection performance. The models were trained and tested on NUAA and Replay-Attack datasets, with cross-dataset generalization validated on SiW-MV2 to assess real-world adaptability. Performance was evaluated using accuracy, precision, recall, FAR, FRR, HTER, and specialized spoof detection metrics (APCER, NPCER, ACER). Fine-tuning significantly improved detection accuracy, with DenseNet201 achieving the highest… More > Graphic Abstract

Tawfeeq Shawly¹, Ahmed A. Alsheikhy^2,*

CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 4161-4179, 2025, DOI:10.32604/cmc.2025.061497 - 06 March 2025

Abstract A healthy brain is vital to every person since the brain controls every movement and emotion. Sometimes, some brain cells grow unexpectedly to be uncontrollable and cancerous. These cancerous cells are called brain tumors. For diagnosed patients, their lives depend mainly on the early diagnosis of these tumors to provide suitable treatment plans. Nowadays, Physicians and radiologists rely on Magnetic Resonance Imaging (MRI) pictures for their clinical evaluations of brain tumors. These evaluations are time-consuming, expensive, and require expertise with high skills to provide an accurate diagnosis. Scholars and industrials have recently partnered to implement… More >

Amel Ksibi^1,*, Mohammed Zakariah², Latifah Almuqren¹, Ala Saleh Alluhaidan¹

CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 4093-4116, 2025, DOI:10.32604/cmc.2025.059615 - 06 March 2025

Abstract The analysis of Android malware shows that this threat is constantly increasing and is a real threat to mobile devices since traditional approaches, such as signature-based detection, are no longer effective due to the continuously advancing level of sophistication. To resolve this problem, efficient and flexible malware detection tools are needed. This work examines the possibility of employing deep CNNs to detect Android malware by transforming network traffic into image data representations. Moreover, the dataset used in this study is the CIC-AndMal2017, which contains 20,000 instances of network traffic across five distinct malware categories: a.… More >

Mohammed Salih Ahmed¹, Atta Rahman^2,*, Yahya Alhabboub¹, Khalid Alzahrani¹, Hassan Baragbah¹, Basel Altaha¹, Hussein Alkatout¹, Sardar Asad Ali Biabani^3,4, Rashad Ahmed⁵, Aghiad Bakry²

Intelligent Automation & Soft Computing, Vol.40, pp. 149-175, 2025, DOI:10.32604/iasc.2025.059080 - 12 February 2025

Abstract This study rigorously evaluates the potential of transfer learning in diagnosing retinal eye diseases using advanced models such as YOLOv8, Xception, ConvNeXtTiny, and VGG16. All models were trained on the esteemed RFMiD dataset, which includes images classified into six critical categories: Diabetic Retinopathy (DR), Macular Hole (MH), Diabetic Neuropathy (DN), Optic Disc Changes (ODC), Tesselated Fundus (TSLN), and normal cases. The research emphasizes enhancing model performance by prioritizing recall metrics, a crucial strategy aimed at minimizing false negatives in medical diagnostics. To address the challenge of imbalanced data, we implemented effective preprocessing techniques, including cropping,… More >

WEITAO ZHENG¹, DONG JIANG², SONGEN CHEN¹, MEILING WU¹, BAOQI YAN², JIAHUI ZHAI², YUNQIANG SHI², BIN XIE¹, XINGWANG XIE², KANGHONG HU^1,*, WENXUE MA^3,*

Oncology Research, Vol.32, No.12, pp. 1837-1850, 2024, DOI:10.32604/or.2024.056565 - 13 November 2024

Abstract Objectives: The Kirsten rat sarcoma virus (KRAS) G12D oncogenic mutation poses a significant challenge in treating solid tumors due to the lack of specific and effective therapeutic interventions. This study aims to explore innovative approaches in T cell receptor (TCR) engineering and characterization to target the KRAS G12D_7-16 mutation, providing potential strategies for overcoming this therapeutic challenge. Methods: In this innovative study, we engineered and characterized two T cell receptors (TCRs), KDA11-01 and KDA11-02 with high affinity for the KRAS G12D_7-16 mutation. These TCRs were isolated from tumor-infiltrating lymphocytes (TILs) derived from tumor tissues of patients More >

Saad Akbar^1,2, Humera Azam¹, Sulaiman Sulmi Almutairi^3,*, Omar Alqahtani⁴, Habib Shah⁴, Aliya Aleryani⁴

CMC-Computers, Materials & Continua, Vol.80, No.1, pp. 1075-1104, 2024, DOI:10.32604/cmc.2024.050913 - 18 July 2024

Abstract The prompt spread of COVID-19 has emphasized the necessity for effective and precise diagnostic tools. In this article, a hybrid approach in terms of datasets as well as the methodology by utilizing a previously unexplored dataset obtained from a private hospital for detecting COVID-19, pneumonia, and normal conditions in chest X-ray images (CXIs) is proposed coupled with Explainable Artificial Intelligence (XAI). Our study leverages less preprocessing with pre-trained cutting-edge models like InceptionV3, VGG16, and VGG19 that excel in the task of feature extraction. The methodology is further enhanced by the inclusion of the t-SNE (t-Distributed… More >

Awais Khan¹, Chomyong Kim², Jung-Yeon Kim², Ahsan Aziz¹, Yunyoung Nam^3,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1729-1755, 2024, DOI:10.32604/cmes.2024.049618 - 20 May 2024

Abstract Sleep posture surveillance is crucial for patient comfort, yet current systems face difficulties in providing comprehensive studies due to the obstruction caused by blankets. Precise posture assessment remains challenging because of the complex nature of the human body and variations in sleep patterns. Consequently, this study introduces an innovative method utilizing RGB and thermal cameras for comprehensive posture classification, thereby enhancing the analysis of body position and comfort. This method begins by capturing a dataset of sleep postures in the form of videos using RGB and thermal cameras, which depict six commonly adopted postures: supine,… More > Graphic Abstract