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  • Open Access


    Performance Comparison of Deep CNN Models for Detecting Driver’s Distraction

    Kathiravan Srinivasan1, Lalit Garg2,*, Debajit Datta3, Abdulellah A. Alaboudi4, N. Z. Jhanjhi5, Rishav Agarwal3, Anmol George Thomas1

    CMC-Computers, Materials & Continua, Vol.68, No.3, pp. 4109-4124, 2021, DOI:10.32604/cmc.2021.016736

    Abstract According to various worldwide statistics, most car accidents occur solely due to human error. The person driving a car needs to be alert, especially when travelling through high traffic volumes that permit high-speed transit since a slight distraction can cause a fatal accident. Even though semi-automated checks, such as speed detecting cameras and speed barriers, are deployed, controlling human errors is an arduous task. The key causes of driver’s distraction include drunken driving, conversing with co-passengers, fatigue, and operating gadgets while driving. If these distractions are accurately predicted, the drivers can be alerted through an alarm system. Further, this research… More >

  • Open Access


    Correlation Analysis of New Soybean [Glycine max (L.) Merr] Gene Gm15G117700 with Oleic Acid

    Shuo Qu1, Yaolei Jiao2, Lamboro Abraham2, Piwu Wang1,*

    Phyton-International Journal of Experimental Botany, Vol.90, No.4, pp. 1177-1192, 2021, DOI:10.32604/phyton.2021.015206

    Abstract The fatty acid dehydrogenase gene plays an important role in regulating the oleic acid content in soybean. Genome-wide association study screened out soybean oleic acid related gene Gm15G117700. A fragment size of 693bp was obtained by PCR amplification of the gene and, it was connected by seamless cloning technology to the pMD18T cloning vector. Based on the gene sequence cloned, bioinformatic analysis of gene protein was performed. The overexpression vector of Gm15G117700 and the CRISPR/Cas9 gene editing vector were constructed. The positive plants were obtained by Agrobacterium-mediated transformation of soybean cotyledon nodes and T2 plants were identified by conventional PCR,… More >

  • Open Access


    TUG1 Indicate Unfavorable Prognosis of Gastric Cancer for Promoting Proliferation, Migration and Multidrug Resistance

    Yuan Liu1,2,#, Yun Jia3, Bing Zhang2, Anwen Liu1,*

    Oncologie, Vol.23, No.1, pp. 61-72, 2021, DOI:10.32604/Oncologie.2021.015906

    Abstract Gastric cancer (GC) is the most common digestive system malignant tumor and second most common cause of cancer-related death. Even for the early gastric cancer, after radical operation, perioperative and postoperative chemotherapy the recurrence and metastasis are also high. 5-year overall survival of all GC patients is only 10–15%. Chemo-resistance still poses a major obstacle to successful treatment of GC. The aberrant expression of TUG1 (Taurine Upregulated Gene 1) was closely related to chemo-resistance and metastasis in many cancers. Here we over-expressed TUG1 in GC cell line SGC-7901 and MGC-803. We compared the migration ability and sensitivity of cisplatin (CDDP),… More >

  • Open Access


    Classification of Emergency Responses to Fatal Traffic Accidents in Chinese Urban Areas

    Pengfei Gong1,2, Qun Wang2,*, Junjun Zhu3

    CMC-Computers, Materials & Continua, Vol.68, No.1, pp. 1389-1408, 2021, DOI:10.32604/cmc.2021.016483

    Abstract Fatal traffic accidents in urban areas can adversely affect the urban road traffic system and pose many challenges for urban traffic management. Therefore, it is necessary to first classify emergency responses to such accidents and then handle them quickly and correctly. The aim of this paper is to develop an evaluation index system and to use appropriate methods to investigate emergency-response classifications to fatal traffic accidents in Chinese urban areas. This study used a multilevel hierarchical structural model to determine emergency-response classification. In the model, accident attributes, urban road network vulnerability, and institutional resilience were used as classification criteria. Each… More >

  • Open Access


    RETRACTED: LncRNA TUG1 Targets miR-222-3p to Take Part in Proliferation and Invasion of Breast Cancer Cells

    Yuqin Xie1, Shuang Deng1, Qian Deng2, Jiudong Xu*

    Oncologie, Vol.22, No.3, pp. 179-188, 2020, DOI:10.32604/Oncologie.2020.012544

    Abstract This study aimed to explore LncRNA TUG1 targeted miR-222-3p in the proliferation and invasion of breast cancer (BC) cells. Seventy-six BC patients admitted to our hospital and 62 health check-ups at the same time were selected as the research objects. Among them, the former was seen as the observation group (OG), and the latter was considered as the control group (CG). The clinical significance of LncRNA TUG1 and miR-222-3p in BC was detected. Human BC cell MCF7 and normal human breast epithelial cell MCF-10A were purchased. After cells were transfected with LncRNA TUG1 and miR-222-3p, their proliferation, invasion, and apoptosis… More >

  • Open Access


    Carbon Monoxide Signal Breaks Primary Seed Dormancy by Transcriptional Silence of DOG1 in Arabidopsis thaliana

    Danni He, Guoli Deng, Songpei Ying, Wenjuan Yang, Jiali Wei, Ping Li*

    Phyton-International Journal of Experimental Botany, Vol.89, No.3, pp. 633-643, 2020, DOI:10.32604/phyton.2020.010498

    Abstract Primary seed dormancy is an adaptive strategy that prevents germination for viable seeds in harsh environment, ensuring seeds germination under favorable condition. Accurately inducing seeds germination in a controllable manner is important for crop production. Thus searching the chemicals that efficiently breaks seed dormancy is valuable. DOG1 protein abundance in the freshly harvested seed is high, and its level is correlated to seed dormancy intensity, thus DOG1 is regarded as the timer to evaluate the seed dormancy degree. In this study, we found the carbon monoxide (CO) donor treatment, the transgenic line with high CO content, showed lower seed dormancy,… More >

  • Open Access


    Teaching an Old Dog a New Trick: Multifaceted Strategies to Control Primary Seed Germination by DELAY OF GERMINATION 1 (DOG1)

    Ping Li*, Huanhuan Ni, Songbei Ying, Jiali Wei, Xiangyang Hu

    Phyton-International Journal of Experimental Botany, Vol.89, No.1, pp. 1-12, 2020, DOI:10.32604/phyton.2020.09817

    Abstract Primary seed dormancy is a critical trait for sustainable agricultural development, ensuring seed germination under favorable conditions. The induction, maintenance and release of seed dormancy is a complicated physiological process that is strictly controlled by a variety of endogenous signals and environmental factors. In Arabidopsis, DOG1 (DELAY OF GERMINATION 1) is identi- fied as the main quantitative trait locus (QTL) of seed dormancy, which contributes to deep dormancy in the Cvi ecotype. In recent years, considerable progress has been made to elucidate the molecular regulatory mechanism by which DOG1 controls seed dormancy. In this review, we describe a series of… More >

  • Open Access


    A Lane Detection Method Based on Semantic Segmentation

    Ling Ding1, 2, Huyin Zhang1, *, Jinsheng Xiao3, *, Cheng Shu3, Shejie Lu2

    CMES-Computer Modeling in Engineering & Sciences, Vol.122, No.3, pp. 1039-1053, 2020, DOI:10.32604/cmes.2020.08268

    Abstract This paper proposes a novel method of lane detection, which adopts VGG16 as the basis of convolutional neural network to extract lane line features by cavity convolution, wherein the lane lines are divided into dotted lines and solid lines. Expanding the field of experience through hollow convolution, the full connection layer of the network is discarded, the last largest pooling layer of the VGG16 network is removed, and the processing of the last three convolution layers is replaced by hole convolution. At the same time, CNN adopts the encoder and decoder structure mode, and uses the index function of the… More >

  • Open Access


    Association between preterm birth risk and polymorphism and expression of the DNA repair genes OGG1 and APE1 in Saudi women

    Arwa Osama NEMER1, Mohammad Saud AL ANAZI2, Ramesa Shafi BHAT1*, Arjumand S. WARSY3, Zeneb A BABAY4, Mohammad H. ADDAR4, Jilani SHAIK2, Sooad AL-DAIHAN1

    BIOCELL, Vol.42, No.1, pp. 1-6, 2018, DOI:10.32604/biocell.2018.07005

    Abstract Genomic instability and mutations caused by increases in oxidative stress during pregnancy can damage the fetoplacental unit and can upshot preterm birth. Oxidative damage to DNA may possibly be involved in etiology of preterm birth (PTB) which can be repaired by DNA repair gene. In the present study, we assessed the association of base excision repair gene family by analyzing the association of single nucleotide polymorphisms and genes expression in 8-oxoguanine glycosylase-1 (OGG1) and apurinic-apyrimidinic endonuclease 1 (APE1) genes with risk of preterm birth in Saudi women. We analyzed genotypes of four single nucleotide polymorphisms (SNPs) (rs1052133, rs293795, rs2072668 and… More >

  • Open Access


    XRCC1 Arg399Gln and Arg194Trp polymorphisms regulate XRCC1 expression and chemoresistance of non-small cell lung cancer cells

    Dairong LI1, Xianlu ZHUO1,2, Lumi HUANG1, Xiaohui JI1, Donglin WANG1

    BIOCELL, Vol.43, No.3, pp. 139-144, 2019, DOI:10.32604/biocell.2019.06460

    Abstract X-ray repair cross-complementing protein 1 (XRCC1) could repair cisplatin-induced DNA damage. XRCC1 Arg399Gln and Arg194Trp variants alter XRCC1 expression and function, leading to changes in cancer sensitivity to cisplatin treatment. This study aimed to investigate the effects of XRCC1 Arg399Gln and Arg194Trp polymorphisms on cell viability, apoptosis and XRCC1 expression in cisplatin-sensitive A549 and cisplatin-resistant A549/DDP nonsmall cell lung cancer (NSCLC) cells. Plasmids carrying XRCC1 Arg399Gln and Arg194Trp were constructed and transfected into A549 and A549/DDP cells. RT–PCR, Western blot, MTT assay, and flow cytometry analysis were performed to assess cell viability, apoptosis, and XRCC1 expression. Compared to control cells,… More >

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