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  • Open Access

    PROCEEDINGS

    Wire Arc Directed Energy Deposited High Performance Aluminium Alloy

    Xuewei Fang1,2,*, Jiannan Yang1, Ke Huang1, Bingheng Lu1,2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.32, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.012410

    Abstract Wire and Arc Additive Manufacturing (WAAM) technology has the advantages of high-efficiency and low-cost to fabricate large-scaled components with medium-complexity. 2319 aluminum alloy is a widely used in aerospace and military industries. Problems of porosity, residual stress, distortion, and poor mechanical properties were focused on in this paper. The mechanism of defect formation during fabrication and strengthening mechanism of peening process were investigated. In order to learn the droplet transfer and molten pool flow behavior, CFD models of molten pools for the pulse mode of CMT (CMT + P) and pulse reverse polarity CMT mode… More >

  • Open Access

    PROCEEDINGS

    Influence of Synchronous-Hammer-Forging Force on the Microstructure and Properties of Laser Directed Energy Deposition 316L Components

    Yunfei Li1, Dongjiang Wu1, Fangyong Niu1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.012365

    Abstract The plastic deformation assisted method plays a positive role in regulating the microstructure and mechanical properties of metal components in additive manufacturing. In this work, the effect of hammer forging force on the microstructure and mechanical properties of 316L stainless steel additive components were investigated by using synchronous-hammer-forging-assisted laser directed energy deposition method. The results show that when the hammer forging force is greater than 40 N, the grain refinement effect is obvious, the grain size decreases by more than 60 %, and the maximum strength of the polar diagram decreases by more than 75 More >

  • Open Access

    ARTICLE

    Numerical Investigations on Fluid Flow and Heat Transfer Characteristics of an Ultra-Thin Heat Pipe with Separated Wick Structures

    Yasushi Koito1,*, Akira Fukushima2

    Frontiers in Heat and Mass Transfer, Vol.22, No.3, pp. 869-887, 2024, DOI:10.32604/fhmt.2024.050910 - 11 July 2024

    Abstract Thermal and fluid-flow characteristics were numerically analyzed for ultra-thin heat pipes. Many studies have been conducted for ultra-thin heat pipes with a centered wick structure, but this study focused on separated wick structures to increase the evaporation/condensation surface areas within the heat pipe and to reduce the concentration of heat flux within the wick structure. A mathematical heat-pipe model was made in the three-dimensional coordinate system, and the model consisted of three regions: a vapor channel, liquid-wick, and container wall regions. The conservation equations for mass, momentum, and energy were solved numerically with boundary conditions… More >

  • Open Access

    ARTICLE

    A Numerical Investigation of the Effect of Boundary Conditions on Acoustic Pressure Distribution in a Sonochemical Reactor Chamber

    Ivan Sboev1,*, Tatyana Lyubimova2,3, Konstantin Rybkin3, Michael Kuchinskiy2,3

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.6, pp. 1425-1439, 2024, DOI:10.32604/fdmp.2024.051341 - 27 June 2024

    Abstract The intensification of physicochemical processes in the sonochemical reactor chamber is widely used in problems of synthesis, extraction and separation. One of the most important mechanisms at play in such processes is the acoustic cavitation due to the non-uniform distribution of acoustic pressure in the chamber. Cavitation has a strong impact on the surface degradation mechanisms. In this work, a numerical calculation of the acoustic pressure distribution inside the reactor chamber was performed using COMSOL Multiphysics. The numerical results have revealed the dependence of the structure of the acoustic pressure field on the boundary conditions More > Graphic Abstract

    A Numerical Investigation of the Effect of Boundary Conditions on Acoustic Pressure Distribution in a Sonochemical Reactor Chamber

  • Open Access

    ARTICLE

    Study of Flow and Heat Transfer in an Ejector-Driven Swirl Anti-Icing Chamber

    Yi Tu1,*, Yuan Wu2, Yu Zeng3

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 989-1014, 2024, DOI:10.32604/fdmp.2024.045624 - 07 June 2024

    Abstract The formation of ice on the leading edge of aircraft engines is a serious issue, as it can have catastrophic consequences. The Swirl Anti-Icing (SAI) system, driven by ejection, circulates hot fluid within a 360° annular chamber to heat the engine inlet lip surface and prevent icing. This study employs a validated Computational Fluid Dynamics (CFD) approach to study the impact of key geometric parameters of this system on flow and heat transfer characteristics within the anti-icing chamber. Additionally, the entropy generation rate and exergy efficiency are analyzed to assess the energy utilization in the… More >

  • Open Access

    ARTICLE

    Preclinical evaluation of cyclophosphamide and fludarabine combined with CD19 CAR-T in the treatment of B-cell hematologic malignancies in vivo

    ZHIGANG XIA1,#, MENGYAO TIAN1,#, YUCAI CHENG1, WENFANG YI1, ZEFAN DU1,2, TIANWEN LI1,2, YUCHEN WEN1, LINDI LI1,2, YONG LIU1,2,*, CHUN CHEN1,*

    Oncology Research, Vol.32, No.6, pp. 1109-1118, 2024, DOI:10.32604/or.2024.049792 - 23 May 2024

    Abstract Background: Chimeric antigen receptor T (CAR-T) cell therapy has achieved marked therapeutic success in ameliorating hematological malignancies. However, there is an extant void in the clinical guidelines concerning the most effective chemotherapy regimen prior to chimeric antigen receptor T (CAR-T) cell therapy, as well as the optimal timing for CAR-T cell infusion post-chemotherapy. Materials and Methods: We employed cell-derived tumor xenograft (CDX) murine models to delineate the optimal pre-conditioning chemotherapy regimen and timing for CAR-T cell treatment. Furthermore, transcriptome sequencing was implemented to identify the therapeutic targets and elucidate the underlying mechanisms governing the treatment regimen.… More >

  • Open Access

    ARTICLE

    Comparison of QT Correction Methods in the Pediatric Population of a Community Hospital: A Retrospective Study

    Koren Hyogene Kwag1,*, Ibrahim Kak1, Ying Li2, Walid Khass1, Alec McKechnie1, Oksana Nulman1, Brande Brown1, Manoj Chhabra1

    Congenital Heart Disease, Vol.19, No.1, pp. 107-121, 2024, DOI:10.32604/chd.2024.045953 - 20 March 2024

    Abstract Objective: Accurate measurement of QT interval, the ventricular action potential from depolarization to repolarization, is important for the early detection of Long QT syndrome. The most effective QT correction (QTc) formula has yet to be determined in the pediatric population, although it has intrinsically greater extremes in heart rate (HR) and is more susceptible to errors in measurement. The authors of this study compare six different QTc methods (Bazett, Fridericia, Framingham, Hodges, Rautaharju, and a computer algorithm utilizing the Bazett formula) for consistency against variations in HR and RR interval. Methods: Descriptive Retrospective Study. We… More >

  • Open Access

    ARTICLE

    Novelty of Different Distance Approach for Multi-Criteria Decision-Making Challenges Using q-Rung Vague Sets

    Murugan Palanikumar1, Nasreen Kausar2,*, Dragan Pamucar3,4, Seifedine Kadry5,6,7,*, Chomyong Kim8, Yunyoung Nam9

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3353-3385, 2024, DOI:10.32604/cmes.2024.031439 - 11 March 2024

    Abstract In this article, multiple attribute decision-making problems are solved using the vague normal set (VNS). It is possible to generalize the vague set (VS) and q-rung fuzzy set (FS) into the q-rung vague set (VS). A log q-rung normal vague weighted averaging (log q-rung NVWA), a log q-rung normal vague weighted geometric (log q-rung NVWG), a log generalized q-rung normal vague weighted averaging (log Gq-rung NVWA), and a log generalized q-rung normal vague weighted geometric (log Gq-rung NVWG) operator are discussed in this article. A description is provided of the scoring function, accuracy function and operational laws of the log q-rung… More >

  • Open Access

    ARTICLE

    Numerical Simulation of Slurry Diffusion in Fractured Rocks Considering a Time-Varying Viscosity

    Lei Zhu1,2, Bin Liu2, Xuewei Liu2,*, Wei Deng1, Wenjie Yao1, Ying Fan1

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.2, pp. 401-427, 2024, DOI:10.32604/fdmp.2023.041444 - 14 December 2023

    Abstract To analyze the effects of a time-varying viscosity on the penetration length of grouting, in this study cement slurries with varying water-cement ratios have been investigated using the Bingham’s fluid flow equation and a discrete element method. A fluid-solid coupling numerical model has been introduced accordingly, and its accuracy has been validated through comparison of theoretical and numerical solutions. For different fracture forms (a single fracture, a branch fracture, and a fracture network), the influence of the time-varying viscosity on the slurry length range has been investigated, considering the change in the fracture aperture. The More >

  • Open Access

    PROCEEDINGS

    Experimental and Numerical Simulation Study on Axial Drop Hammer Impact of Rubber Modified Non-Autoclaved Concrete Pipe Pile

    Sheng Lan1, Fei Yang1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.09077

    Abstract Non-autoclaved concrete pipe piles are gaining attention as an environmentally friendly alternative to autoclaved concrete pipe piles. The purpose of this study was to investigate the changes in the impact resistance of a non-autoclaved concrete pipe pile with the addition of rubber. To this end, various volume fractions of rubber particles were used to replace the fine sand in the non-autoclaved pipe pile concrete (0%, 5%, 10% and 15%). Additionally, the axial impact resistance of rubber modified non-autoclaved concrete pipe pile was studied from the concrete materials and pipe pile components through quasi-static, dynamic compression… More >

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