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  • Open Access

    ARTICLE

    A Fractional Order HIV Internal Viral Dynamics Model

    Caibin Zeng1, Qigui Yang1

    CMES-Computer Modeling in Engineering & Sciences, Vol.59, No.1, pp. 65-78, 2010, DOI:10.3970/cmes.2010.059.065

    Abstract In this paper, a fractional order model is established to describe HIV internal viral dynamics involving HAART effect. First, the model is proved to possess non-negative solutions as desired in any population dynamics. Then, a detailed analysis is carried out to study the stability of equilibrium points. Numerical simulations are presented to illustrate the stability analysis. More >

  • Open Access

    ARTICLE

    Dynamical Analysis of a Fractional-order HIV Model

    Haiping Ye1, Yongsheng Ding2

    CMES-Computer Modeling in Engineering & Sciences, Vol.49, No.3, pp. 255-268, 2009, DOI:10.3970/cmes.2009.049.255

    Abstract A fractional-order model for the immunological and therapeutic control of HIV is studied qualitatively. The equilibria are found and their local stability are investigated. Also the global stability of the infection-free equilibrium is established. The optimal efficacy level of anti-retroviral therapy needed to eradicate HIV from the body of an HIV-infected individual is obtained. More >

  • Open Access

    ARTICLE

    Stability Analysis for Fractional Differential Equations and Their Applications in the Models of HIV-1 Infection

    Chunhai Kou1, Ye Yan2, Jian Liu1

    CMES-Computer Modeling in Engineering & Sciences, Vol.39, No.3, pp. 301-318, 2009, DOI:10.3970/cmes.2009.039.301

    Abstract In the paper, stability for fractional order differential equations is studied. Then the result obtained is applied to analyse the stability of equilibrium for the model of HIV. More >

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