JUN-FENG ZHAO^1,†, YI-RAN JIANG^2,†, TIAN-LIN GUO¹, YONG-QING JIAO^1,*, XUN WANG^1,*

BIOCELL, Vol.48, No.7, pp. 1011-1022, 2024, DOI:10.32604/biocell.2024.050120

Abstract Neurodegenerative diseases constitute a broad category of diseases caused by the degeneration of the neurons. They are mainly manifested by the gradual loss of neuron structure and function and eventually can cause death or loss of neurons. As the global population ages rapidly, increased people are being diagnosed with neurodegenerative diseases. It has been established that the onset of Alzheimer’s disease (AD) is closely linked with increasing age and its major pathological features include amyloid-beta plaques (Aβ), Tau hyperphosphorylation, Neurofibrillary tangles (NFTs), neuronal death as well as synaptic loss. The involvement of microglia is crucial… More >

Jiaqiong Wang^1,2, Tao Yang¹, Chen Hu¹, Yu Zhang^3,*, Ling Zhou^1,2

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.6, pp. 1203-1218, 2024, DOI:10.32604/fdmp.2023.045825

Abstract To investigate the influence of structural parameters on the performances and internal flow characteristics of partial flow pumps at a low specific speed of 10000 rpm, special attention was paid to the first and second stage impeller guide vanes. Moreover, the impeller blade outlet width, impeller inlet diameter, blade inclination angle, and number of blades were considered for orthogonal tests. Accordingly, nine groups of design solutions were formed, and then used as a basis for the execution of numerical simulations (CFD) aimed at obtaining the efficiency values and heads for each design solution group. The More >

Hailing Yang¹, Suoping Li^1,2,*, Duo Peng²

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 5273-5294, 2024, DOI:10.32604/cmc.2024.050869

Abstract To address the problems of network congestion and spectrum resources shortage in multi-user large-scale scenarios, this paper proposes a twice random access OFDMA-NOMA-RA protocol combining the advantages of orthogonal frequency division multiple access (OFDMA) and non-orthogonal multiple access (NOMA). The idea of this protocol is that OFMDA is used to divide the entire frequency field into multiple orthogonal resource units (RUs), and NOMA is used on each RU to enable more users to access the channel and improve spectrum efficiency. Based on the protocol designed in this paper, in the case of imperfect successive interference… More >

Ahmed H. Alhadethi^1,*, Ikram Smaoui², Ahmed Fakhfakh³, Saad M. Darwish⁴

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4825-4844, 2024, DOI:10.32604/cmc.2024.047852

Abstract The act of transmitting photos via the Internet has become a routine and significant activity. Enhancing the security measures to safeguard these images from counterfeiting and modifications is a critical domain that can still be further enhanced. This study presents a system that employs a range of approaches and algorithms to ensure the security of transmitted venous images. The main goal of this work is to create a very effective system for compressing individual biometrics in order to improve the overall accuracy and security of digital photographs by means of image compression. This paper introduces… More >

MINGYUE HUANG^1,#, JUNFEI DAI^1,#, XIANLIANG ZHONG², JIN WANG², JIANZHONG XU², BO DU^2,*

BIOCELL, Vol.48, No.6, pp. 889-896, 2024, DOI:10.32604/biocell.2024.050097

Abstract Chronic subdural hematoma (CSDH) is a disease characterized by capsuled blood products that progressively occupy the intracranial space, causing intracranial hypertension and compression in the brain. CSDH frequently occurs in all demographics, especially in the elderly, but the pathogenesis of CSDH remains unclear. In this review, we discuss the origin, development, and current treatment strategies of CSDH. For the first time, we analyzed the cellular and molecular compositions of hematoma membranes with a focus on neomembrane formation, a complex early-stage interactive event in hematoma pathogenesis. We hypothesize that in patients with CSDH, dural border cells… More >

Alexis Salazar-Navarro¹, Victor Ruiz-Valdiviezo², Jose Joya-Dávila³, Daniel Gonzalez-Mendoza^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 923-949, 2024, DOI:10.32604/phyton.2024.049612

Abstract Coffee Leaf Rust (CLR) is caused by Hemileia vastatrix in Coffea spp. It is one of the most dangerous phytopathogens for coffee plantations in terms of coffee productivity and coffee cup quality. In this review, we resume the problem of CLR in Mexico and the pathogenesis of H. vastatrix. The review abord plant-pathogen interactions which lead a compatible or incompatible interactions and result in CLR disease or resistance, respectively. The review abord Coffea spp. defense response pathways involved in H. vastatrix pathogenicity. Additionally, current measures to control H. vastatrix proliferation and germination were aborded focused on phytosanitary actions, and biological More >

Xinlu Liu, Xiaodong Tan, Peng Liu, Yunhao Wu, Songying Qian, Xiaobo Zhang

Oncology Research, Vol.26, No.7, pp. 1123-1131, 2018, DOI:10.3727/096504018X15166223632406

Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive tumors known, with an overall 5-year survival rate of less than 6% due to early local invasion and distant metastasis. Exploring suitable therapeutic targets associated with invasion and metastasis is required for improving the prognosis of PDAC. In this study, we investigated the role of the glycolytic enzyme phosphoglycerate mutase 1 (PGAM1) in PDAC. PGAM1 expression was examined in tissue samples of 54 PDAC patients using immunohistochemistry, and the correlation between clinicopathological expression and PGAM1 expression was determined. A survival curve was generated using the… More >

Lassaad K. Smirani¹, Leila Jamel^2,*, Latifah Almuqren²

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1315-1337, 2024, DOI:10.32604/cmes.2024.047551

Abstract This study presents a layered generalization ensemble model for next generation radio mobiles, focusing on supervised channel estimation approaches. Channel estimation typically involves the insertion of pilot symbols with a well-balanced rhythm and suitable layout. The model, called Stacked Generalization for Channel Estimation (SGCE), aims to enhance channel estimation performance by eliminating pilot insertion and improving throughput. The SGCE model incorporates six machine learning methods: random forest (RF), gradient boosting machine (GB), light gradient boosting machine (LGBM), support vector regression (SVR), extremely randomized tree (ERT), and extreme gradient boosting (XGB). By generating meta-data from five… More >

TINGTING LIU^1,#, YIWEI HAO^2,#, LIFENG ZHAO^2,*

BIOCELL, Vol.48, No.5, pp. 707-729, 2024, DOI:10.32604/biocell.2024.049130

Abstract Parkinson’s disease (PD) is a common neurodegenerative disease in the elderly, accounting for more than 1% of the population aged 65 years. Monogenic inheritance is relatively rare in PD, accounting for approximately 5% to 10% of PD patients, and there is a growing body of evidence suggesting that multiple genetic risk factors play a significant role in the pathogenesis of PD. Several groups have identified and reported a number of genes carrying mutations associated with affected family members. Mutated genes associated with PD are also candidates for idiopathic PD, and these genes may also carry… More >

FREDERICK H. SILVER^1,2,*, TANMAY DESHMUKH²

BIOCELL, Vol.48, No.4, pp. 525-540, 2024, DOI:10.32604/biocell.2024.047965

Abstract All tissues in the body are subjected externally to gravity and internally by collagen fibril and cellular retractive forces that create stress and energy equilibrium required for homeostasis. Mechanotransduction involves mechanical work (force through a distance) and energy storage as kinetic and potential energy. This leads to changes in cell mitosis or apoptosis and the synthesis or loss of tissue components. It involves the application of energy directly to cells through integrin-mediated processes, cell-cell connections, stretching of the cell cytoplasm, and activation of the cell nucleus via yes-associated protein (YAP) and transcriptional coactivator with PDZ-motif… More >