XIAOQI WU^1,2,#, YECHUAN HE^1,2,#, YEQIN YUAN⁴, XIAN TAN^1,2, LIN ZHU^1,2, DANLING WANG^1,2,4, BINYUAN JIANG^3,4,*

BIOCELL, Vol.48, No.5, pp. 861-872, 2024, DOI:10.32604/biocell.2024.048758

Abstract Background: Nasopharyngeal carcinoma (NPC) exhibits a significant prevalence in the southern regions of China, and paclitaxel (PTX) is frequently employed as a medication for managing advanced NPC. However, drug resistance is typically accompanied by a poor prognosis. Exploring the synergistic potential of combining multiple chemotherapeutic agents may represent a promising avenue for optimizing treatment efficacy. Methods: This study investigated whether 3-Methyladenine (3-MA) could potentiated the effect of PTX and its potential molecular mechanism. Samples were divided into the following categories: Negative control (NC) with the solvent dimethyl sulfoxide (DMSO, 0.5% v/v), PTX (400 nM), 3-MA (4 mM), and PTX (400… More >

Khaled Soliman^1,*, Mohamed Sobh², Ayman M. Bahaa-Eldin²

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1419-1439, 2024, DOI:10.32604/cmc.2024.048883

Abstract The continuous development of cyberattacks is threatening digital transformation endeavors worldwide and leads to wide losses for various organizations. These dangers have proven that signature-based approaches are insufficient to prevent emerging and polymorphic attacks. Therefore, this paper is proposing a Robust Malicious Executable Detection (RMED) using Host-based Machine Learning Classifier to discover malicious Portable Executable (PE) files in hosts using Windows operating systems through collecting PE headers and applying machine learning mechanisms to detect unknown infected files. The authors have collected a novel reliable dataset containing 116,031 benign files and 179,071 malware samples from diverse sources to ensure the efficiency… More >

Fangjun Luan^1,2,3, Xuewen Mu^1,2,3, Shuai Yuan^1,2,3,*

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 695-712, 2024, DOI:10.32604/cmc.2024.048502

Abstract Online Signature Verification (OSV), as a personal identification technology, is widely used in various industries. However, it faces challenges, such as incomplete feature extraction, low accuracy, and computational heaviness. To address these issues, we propose a novel approach for online signature verification, using a one-dimensional Ghost-ACmix Residual Network (1D-ACGRNet), which is a Ghost-ACmix Residual Network that combines convolution with a self-attention mechanism and performs improvement by using Ghost method. The Ghost-ACmix Residual structure is introduced to leverage both self-attention and convolution mechanisms for capturing global feature information and extracting local information, effectively complementing whole and local signature features and mitigating… More >

ÇAĞLA GÜL GÜLDİKEN, LEVENT AKYALÇIN, HASAN FERDİ GERÇEL^*

Journal of Polymer Materials, Vol.36, No.4, pp. 337-349, 2019, DOI:10.32381/JPM.2019.36.04.4

Abstract In the present study, polybenzimidazole (PBI) polymer which has a great importance in polymer electrolyte membrane (PEM) research was synthesized via the solution polycondensation method, under various synthesis conditions to put forward the effect of the synthesis parameters on the properties of the synthesized polymer and consequently to the quality of the prepared polymer electrolyte membrane. The synthesized polymers were characterized in terms of their chemical structure, thermal degradation behaviour, and molecular weight by Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance spectroscopy (¹ H NMR), thermogravimetric analysis (TGA). The Mechanical properties, acid-doping level capacity, proton conductivity, and fuel cell… More >

RAJKUMAR SINGH RAWAT^1,2, MEENU TALWAR^1,*, RAJENDRA KUMAR DIWAN², AJAY KUMAR TYAGI¹

Journal of Polymer Materials, Vol.38, No.3-4, pp. 281-294, 2021, DOI:10.32381/JPM.2021.38.3-4.9

Abstract In the present paper,boron based diluent was synthesized and incorporated in to a Ultraviolet (UV) radiation curable epoxy coating composition comprising of phosphorus based initiator (Trimethylbenzoyl diphenyl phosphine oxide) for enhancing its flame retardant property. The boron based diluent was synthesized by thermal polymerization technique. The presence of boron and phosphorus on the coating surface was confirmed by Energy Dispersive X-Ray (EDX) and X-ray photoelectron spectroscopy (XPS) techniques and functionality was determination by Fourier Transform Infra-Red (FTIR) and proton/boron NMR spectroscopy technique. The flame retardency property of the coating composition was confirmed by determining limiting oxygen index,vertical burning test, rate… More >

Chun Mao¹, Ji He^1,*, Xuefeng Wen¹, Yangzhou Xiang², Jihong Feng¹, Yingge Shu¹

Phyton-International Journal of Experimental Botany, Vol.93, No.3, pp. 487-502, 2024, DOI:10.32604/phyton.2024.048246

Abstract The contents of carbon (C), nitrogen (N), and phosphorus (P) in soil-microorganisms-plant significantly affect tea quality by altering the main quality components of tea, such as tea polyphenols, amino acids, and caffeine. However, few studies have quantified the effects of these factors on the main quality components of tea. The study aimed to explore the interactions of C, N, and P in soil-microorganisms-plants and the effects of these factors on the main quality components of tea by using the path analysis method. The results indicated that (1) The contents of C, N, and P in soil, microorganisms, and tea plants… More >

Jianlong Jin, Jingjing Ding, Long Xiong, Ming Bao, Peng Zeng^*

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.4, pp. 803-814, 2024, DOI:10.32604/fdmp.2023.027311

Abstract The effects of different contents of a MgO expansive agent and phosphorus slag on the mechanical properties, shrinkage behavior, and the heat of hydration of concrete were studied. The slump flow, setting time, dry shrinkage, and hydration heat were used as sensitive parameters to assess the response of the considered specimens. As shown by the results, in general, with an increase in the phosphorus slag content, the hydration heat of concrete decreases for all ages, but the early strength displays a downward trend and the dry shrinkage rate increases. The 90-d strength and dry shrinkage of concrete could be improved… More > Graphic Abstract

Zhongping Liu¹, Enhui Sun^2,*, Jiahao Shi², Lei Zhang², Qi Wang¹, Jiali Dong¹

Energy Engineering, Vol.121, No.4, pp. 913-932, 2024, DOI:10.32604/ee.2023.043973

Abstract There is a growing need to explore the potential of coal-fired power plants (CFPPs) to enhance the utilization rate of wind power (wind) and photovoltaic power (PV) in the green energy field. This study developed a load regulation model for a multi-power generation system comprising wind, PV, and coal energy storage using real-world data. The power supply process was divided into eight fundamental load regulation scenarios, elucidating the influence of each scenario on load regulation. Within the framework of the multi-power generation system with the wind (50 MW) and PV (50 MW) alongside a CFPP (330 MW), a lithium-iron phosphate… More > Graphic Abstract

Koren Hyogene Kwag^1,*, Ibrahim Kak¹, Ying Li², Walid Khass¹, Alec McKechnie¹, Oksana Nulman¹, Brande Brown¹, Manoj Chhabra¹

Congenital Heart Disease, Vol.19, No.1, pp. 107-121, 2024, DOI:10.32604/chd.2024.045953

Abstract Objective: Accurate measurement of QT interval, the ventricular action potential from depolarization to repolarization, is important for the early detection of Long QT syndrome. The most effective QT correction (QTc) formula has yet to be determined in the pediatric population, although it has intrinsically greater extremes in heart rate (HR) and is more susceptible to errors in measurement. The authors of this study compare six different QTc methods (Bazett, Fridericia, Framingham, Hodges, Rautaharju, and a computer algorithm utilizing the Bazett formula) for consistency against variations in HR and RR interval. Methods: Descriptive Retrospective Study. We included participants from a pediatric… More >

WEN GE^1,2,#, YA LI^1,2,#, YUTING RUAN^1,2, NINGXIA WU^1,2, PEI MA^3,4, TONGPENG XU^3,4, YONGQIAN SHU^3,4, YINGWEI WANG^1,2, WEN QIU^1,2, CHENHUI ZHAO^3,4,*

Oncology Research, Vol.32, No.4, pp. 625-641, 2024, DOI:10.32604/or.2023.031053

Abstract The cancer cell metastasis is a major death reason for patients with non-small cell lung cancer (NSCLC). Although researchers have disclosed that interleukin 17 (IL-17) can increase matrix metalloproteinases (MMPs) induction causing NSCLC cell metastasis, the underlying mechanism remains unclear. In the study, we found that IL-17 receptor A (IL-17RA), p300, p-STAT3, Ack-STAT3, and MMP19 were up-regulated both in NSCLC tissues and NSCLC cells stimulated with IL-17. p300, STAT3 and MMP19 overexpression or knockdown could raise or reduce IL-17-induced p-STAT3, Ack-STAT3 and MMP19 level as well as the cell migration and invasion. Mechanism investigation revealed that STAT3 and p300 bound… More > Graphic Abstract