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  • Open Access

    REVIEW

    The Prevalence of Congenital Heart Disease among School-Age Children in China: A Meta-Analysis and Systematic Review

    Shuqin Zhang1,#, Bin Zhang2,#, Jianying Wu3, Jin Luo1, Haomin Shi1, Jirong Qi3,4,*, Huilian Yang1,5,*

    Congenital Heart Disease, Vol.18, No.2, pp. 127-150, 2023, DOI:10.32604/chd.2023.025616

    Abstract Objectives: To estimate the prevalence of Congenital Heart Disease (CHD) in school-age children, to identify the extent to which altitude affects the prevalence of the disease, and to examine trends in prevalence over time in China. Methods: Seven databases were systematically searched and last retrieved on September 10, 2021 for all studies reporting the prevalence of CHD in children after 1970 in China, which were then divided into high and low altitude regions based on 2500 meters above sea level. The random-effected model was used to combine prevalence data and subgroups analysis. The baseline data of all cases and individuals… More > Graphic Abstract

    The Prevalence of Congenital Heart Disease among School-Age Children in China: A Meta-Analysis and Systematic Review

  • Open Access

    ARTICLE

    Cardiac Surgery with Cardiopulmonary Bypass in Low-Weight or Preterm Neonates: A Retrospective Study Analyzing Early Outcome

    Alain J. Poncelet1,*, Maureen Peers de Nieuwburgh2, Stéphane Moniotte2, Geoffroy de Beco1, Karlien Carbonez2, Jean E. Rubay1, Thierry Detaille3, Laurent Houtekie3, Mona Momeni4

    Congenital Heart Disease, Vol.18, No.2, pp. 151-168, 2023, DOI:10.32604/chd.2023.022636

    Abstract Background: Most outcome studies in congenital cardiac surgery for “low weight” neonates include patients undergoing surgery without cardiopulmonary bypass (CPB). The primary objective of our study was to identify risk factors for in-hospital mortality in neonates weighing less than 3 Kg and undergoing surgery with CPB. In addition, we compared the effect of early surgery with CPB (before 37W-gestational age (GA)) for congenital heart disease to delayed surgery until a corrected GA of 37 weeks in an attempt to promote weight gain. Methods: Retrospective single-center study including all patients operated between 1997 and 2017. Uni- and multivariable analysis were used… More >

  • Open Access

    ARTICLE

    Quality of Life in Congenital Heart Disease Patients According to Their Anatomical and Physiological Classification

    Efrén Martínez-Quintana1,2,*, Hiurma Estupiñán-León2, Ana Beatriz Rojas-Brito2, Liuva Déniz-Déniz2, Alejandro Barreto-Martín2, Fayna Rodríguez-González3

    Congenital Heart Disease, Vol.18, No.2, pp. 197-206, 2023, DOI:10.32604/CHD.2021.013308

    Abstract Background: Living well is as important as living longer. The objective of this study is to assess quality of life (QoL) in congenital heart disease (CHD) according to current AHA/ACC anatomical and physiological classifi- cation. Methods: Cross-sectional study examining the World Health Organization QoL Bref questionnaire (WHOQoL-Bref) in consecutive outpatient CHD patients from a single unit. Results: 191 CHD patients were studied. Median age was 28 ± 13 years and 59% were male. 44 (23%), 115 (60%) and 33 (17%) CHD patients showed mild, moderate and great anatomical defects respectively while 69 (36%) patients were in physiological Stage A, 27… More >

  • Open Access

    ARTICLE

    Classifying Big Medical Data through Bootstrap Decision Forest Using Penalizing Attributes

    V. Gowri1,*, V. Vijaya Chamundeeswari2

    Intelligent Automation & Soft Computing, Vol.36, No.3, pp. 3675-3690, 2023, DOI:10.32604/iasc.2023.035817

    Abstract Decision forest is a well-renowned machine learning technique to address the detection and prediction problems related to clinical data. But, the traditional decision forest (DF) algorithms have lower classification accuracy and cannot handle high-dimensional feature space effectively. In this work, we propose a bootstrap decision forest using penalizing attributes (BFPA) algorithm to predict heart disease with higher accuracy. This work integrates a significance-based attribute selection (SAS) algorithm with the BFPA classifier to improve the performance of the diagnostic system in identifying cardiac illness. The proposed SAS algorithm is used to determine the correlation among attributes and to select the optimum… More >

  • Open Access

    ARTICLE

    Classifying Cardiac Anomalies in Right and Left Isomerism: Concordant and Discordant Patterns

    Lilia Oreto1,*, Giuseppe Mandraffino2, Paolo Ciliberti3, Teresa P. Santangelo4, Placido Romeo5, Antonio Celona5, Placido Gitto1, Lorenzo Galletti3, Fiore S. Iorio3, Alfredo Di Pino1, Aurelio Secinaro4, Paolo Guccione3, Robert H. Anderson6, Salvatore Agati1

    Congenital Heart Disease, Vol.18, No.1, pp. 97-111, 2023, DOI:10.32604/chd.2022.023619

    Abstract Aims: Evidence is emerging that, in the setting of isomerism, the atrial and bronchial arrangement are not always concordant, nor are these patterns always harmonious with the arrangement of the abdominal organs. We aimed to evaluate the concordance between these features in a cohort of patients with cardiac malformations in the setting of known isomerism, seeking to determine whether it was feasible to assess complexity on this basis, in this regard taking note of the potential value of bronchial as opposed to appendage morphology. Methods and Results: We studied 78 patients known to have isomerism of the bronchuses, 43 with… More > Graphic Abstract

    Classifying Cardiac Anomalies in Right and Left Isomerism: Concordant and Discordant Patterns

  • Open Access

    ARTICLE

    Assessment of Intracardiac and Extracardiac Deformities in Patients with Various Types of Pulmonary Atresia by Dual-Source Computed Tomography

    Wenlei Qian1,#, Xinzhu Zhou2,#, Ke Shi1, Li Jiang1, Xi Liu3, Liting Shen1, Zhigang Yang1,*

    Congenital Heart Disease, Vol.18, No.1, pp. 113-125, 2023, DOI:10.32604/chd.2023.023542

    Abstract Background: Pulmonary atresia (PA) is a group of heterogeneous complex congenital heart disease. Only one study modality might not get a correct diagnosis. This study aims to investigate the diagnostic power of dual-source computed tomography (DSCT) for all intracardiac and extracardiac deformities in patients with PA compared with transthoracic echocardiography (TTE). Materials and Methods: This retrospective study enrolled 79 patients and divided them into three groups according to their main diagnosis. All associated malformations and clinical information, including treatments, were recorded and compared among the three groups. The diagnostic power of DSCT and TTE on all associated malformations were compared.… More > Graphic Abstract

    Assessment of Intracardiac and Extracardiac Deformities in Patients with Various Types of Pulmonary Atresia by Dual-Source Computed Tomography

  • Open Access

    ARTICLE

    Genetic Analysis of Variants of the MYH6 Gene Promoter in Congenital Atrial Septal Defects

    Ji-Yang Zuo1,2, Huan-Xin Chen1,2, Zhi-Gang Liu1,2, Qin Yang1,2, Guo-Wei He1,2,*

    Congenital Heart Disease, Vol.18, No.1, pp. 7-21, 2023, DOI:10.32604/chd.2022.025451

    Abstract Background: Atrial septal defect (ASD) is one of the common congenital heart diseases. The MYH6 gene has a critical role in cardiac development but the role of MYH6 promoter variants in patients with ASD has not been explored. Methods: In 613 subjects including 320 ASD patients, we investigated the MYH6 gene promoter variants and verified the effect on gene expression by using cellular functional experiments and bioinformatics analysis. Results: Eleven variants were identified in the MYH6 gene promoter, of which four variants were found only in ASD patients, and two variants (g.3434G>C and g.4524C>T) were identified for the first time.… More > Graphic Abstract

    Genetic Analysis of Variants of the <i>MYH6</i> Gene Promoter in Congenital Atrial Septal Defects

  • Open Access

    ARTICLE

    Feature-Limited Prediction on the UCI Heart Disease Dataset

    Khadijah Mohammad Alfadli, Alaa Omran Almagrabi*

    CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 5871-5883, 2023, DOI:10.32604/cmc.2023.033603

    Abstract Heart diseases are the undisputed leading causes of death globally. Unfortunately, the conventional approach of relying solely on the patient’s medical history is not enough to reliably diagnose heart issues. Several potentially indicative factors exist, such as abnormal pulse rate, high blood pressure, diabetes, high cholesterol, etc. Manually analyzing these health signals’ interactions is challenging and requires years of medical training and experience. Therefore, this work aims to harness machine learning techniques that have proved helpful for data-driven applications in the rise of the artificial intelligence era. More specifically, this paper builds a hybrid model as a tool for data… More >

  • Open Access

    ARTICLE

    Healthcare Monitoring Using Ensemble Classifiers in Fog Computing Framework

    P. M. Arunkumar1, Mehedi Masud2, Sultan Aljahdali2, Mohamed Abouhawwash3,4,*

    Computer Systems Science and Engineering, Vol.45, No.2, pp. 2265-2280, 2023, DOI:10.32604/csse.2023.032571

    Abstract Nowadays, the cloud environment faces numerous issues like synchronizing information before the switch over the data migration. The requirement for a centralized internet of things (IoT)-based system has been restricted to some extent. Due to low scalability on security considerations, the cloud seems uninteresting. Since healthcare networks demand computer operations on large amounts of data, the sensitivity of device latency evolved among health networks is a challenging issue. In comparison to cloud domains, the new paradigms of fog computing give fresh alternatives by bringing resources closer to users by providing low latency and energy-efficient data processing solutions. Previous fog computing… More >

  • Open Access

    CASE REPORT

    Neocuspidization of the Pulmonary Valve with Autologous Pericardium in the Adult Patient with Ventricular Septal Defect and Infective Endocarditis: A Case Report and Review of the Literature

    Igor Mokryk1,2,*, Vitaly Demyanchuk1,2, Volodymyr Vashkeba2, Ilya Nechay1, Borys Todurov1,2

    Congenital Heart Disease, Vol.17, No.6, pp. 641-646, 2022, DOI:10.32604/chd.2022.025096

    Abstract Congenital heart disease (CHD) is one of the risk factors for developing infective endocarditis (IE). Right-sided IE occurs in 5%–10% of endocarditis cases, and pulmonary valve (PV) is involved in less than 2% of such patients. Literature data are few, and optimal treatment methods, indications for surgery, and types of operative techniques are still under debate. We present an adult patient with a rare combination of the ventricular septal defect (VSD) and PV IE who underwent surgical treatment. Neocuspidization with autologous pericardium was utilized for the reconstruction of his PV. We discuss details of this novel surgical technique. More > Graphic Abstract

    Neocuspidization of the Pulmonary Valve with Autologous Pericardium in the Adult Patient with Ventricular Septal Defect and Infective Endocarditis: A Case Report and Review of the Literature

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