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  • Open Access

    ABSTRACT

    Contribution as for the Optimization of the Pumping Stations

    A. Alexenadrescu1, A.S. Alex,rescu1, A.C. Alexandrescu1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.8, No.2, pp. 47-58, 2008, DOI:10.3970/icces.2008.008.047

    Abstract The paper follows the analyse of the connections between the constructive, working parameters, the annual energy consumptions and the energy quantity included in fitting out; it will formulate a methodology of establishment of the optimum values of the parameters of admeasurements of the pumping stations for the setting under pressure, of pipes networks, what ensure an optimum consumption of energy during of duty of the fitting out (the operational energy and the included energy in the networks, equipment and constructions), of the conditions after that it can be obtained. It will follow the generalization of the solutions of increase of… More >

  • Open Access

    ABSTRACT

    Physiological Cost Optimization for Bipedal Modeling with Optimal Controller Design

    A. M. Mughal1, K. Iqbal2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.6, No.4, pp. 215-220, 2008, DOI:10.3970/icces.2008.006.215

    Abstract Human voluntary movements are complex physical phenomenon and there are several physiological factors that control the movement and transient response, steady state position, speed of motion and other characteristics. Many experimentalists described variety of variables important for human balance and movement such as center of mass, center of pressure, ground reaction forces etc. In this study, we discuss a bipedal model for biomechanical sit to stand movement with optimal controller design. The cost optimization for gain scheduling is based upon physiological variables of center of mass, head position, and ground reaction forces. Our simulation results shows that movement profiles improve… More >

  • Open Access

    ABSTRACT

    A Failure-Predicting Intelligent PYTHON (IP) Code for Monitoring A Crack of Irregular Shape in A Pipe#

    Jeffrey T. Fong1,*, Pedro V. Marcal2, Robert Rainsberger3, N. A. Heckert1, J. J. Filliben1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.21, No.2, pp. 45-45, 2019, DOI:10.32604/icces.2019.05432

    Abstract When a small crack is detected in a pressure vessel or piping, we can estimate the fatigue life of the vessel or piping by applying the classical law of fracture mechanics for crack growth if we are certain that the crack growth exponent is correct and the crack geometry is a simple plane. Unfortunately, for an ageing vessel or piping, the degradation will change the crack growth exponent, and the crack will advance not in a simple planar fashion. To validate the crack growth exponent for an ageing vessel or piping with a crack of an irregular shape, we design… More >

  • Open Access

    ABSTRACT

    SMA Confinement of HDPE Pipes: Enhancement of the Joint Fracture Resistance

    Eunsoo Choi1,*, Yunkyu Ha1, Duhyeon Kim1, Hoan D. Nguyen1, Tae Yeong Kim1, Seong Jun Park1, Yeon-seong Lee1, Cheolki Min2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.21, No.1, pp. 13-13, 2019, DOI:10.32604/icces.2019.05356

    Abstract This study was to provide a new aspect of application of shape memory alloys (SMAs) in civil engineering. The high-density polyethylene (HDPE) have been used for construction of pipelines for several years. The main problem of using HDPE for pipes is the joint of two adjacent pipes. In case of having a perfect joint, the HDPE pipeline can bare the internal pressure up to 90 MPa. However, in practice, it can rarely achieve to a perfect pipe joint due to the complicated process, so, it prone to fracture in low internal pressure. To overcome this, this study investigated the efficiency… More >

  • Open Access

    ARTICLE

    Fast Multipole Boundary Element Analysis of Corrosion Problems

    S.Aoki1, K.Amaya2, M.Urago3, A.Nakayama4

    CMES-Computer Modeling in Engineering & Sciences, Vol.6, No.2, pp. 123-132, 2004, DOI:10.3970/cmes.2004.006.123

    Abstract The Fast Multipole Boundary Element Method(FMBEM) which is suitable for a large scale computation is applied to corrosion analysis. Many techniques of the FMBEM on the potential problems can be usefully employed. Additionally, some procedures are developed for corrosion analysis. To cope with the non-linearity due to the polarization curve, the Bi-CGSTAB iterative method which is commonly used in the FMBEM is modified. To solve infinite domain problems, the M00 which is obtained naturally in the multipole expansion is conveniently used. A pipe element for the FMBEM is developed. A couple of example problems are solved to show the… More >

  • Open Access

    ARTICLE

    Alteration of Viscoelastic Properties is Associated with a Change in Cytoskeleton Components of Ageing Chondrocytes from Rabbit Knee Articular Cartilage

    Wangping Duan, Lei Wei, Juntao Zhang, Yongzhuang Hao, Chunjiang Li, Hao Li, Qi Li, Quanyou Zhang, Weiyi Chen, Xiaochun Wei∗,§

    Molecular & Cellular Biomechanics, Vol.8, No.4, pp. 253-274, 2011, DOI:10.3970/mcb.2011.008.253

    Abstract The cytoskeleton network is believed to play an important role in the biomechanical properties of the chondrocyte. Ours and other laboratories have demonstrated that chondrocytes exhibit a viscoelastic solid creep behavior in vitro and that viscoelastic properties decrease in osteoarthritic chondrocytes. In this study, we aimed to understand whether the alteration of viscoelastic properties is associated with changes in cytoskeleton components of ageing chondrocytes from rabbit knee articular cartilage. Three age groups were used for this study: young (2-months-old, N=23), adult (8-months-old, N=23), and old (31-months-old, N=23) rabbit groups. Cartilage structure and proteoglycan and type II collagen content were determined… More >

  • Open Access

    ARTICLE

    Adhesive Force of Human Hepatoma HepG2 Cells to Endothelial Cells and Expression of E-Selectin

    Guanbin Song∗,†, Toshiro Ohashi, Naoya Sakamoto, Masaaki Sato

    Molecular & Cellular Biomechanics, Vol.3, No.2, pp. 61-68, 2006, DOI:10.3970/mcb.2006.003.061

    Abstract Expression of adhesion molecules may play an important role in the interaction of tumor cells with vascular endothelial cells during tumor invasion and metastasis. In this study, the adhesive force of human hepatoma HepG2 cells to human umbilical vein endothelial cells (HUVECs) was investigated using a micropipette aspiration technique. Expression of an adhesion molecule, E-selectin, was also observed by immunofluorescence microscopy. In particular, the adhesive force after stimulation of HUVECs with recombinant human interleukin-1β (rhIL-1β) was examined. The results demonstrated that the adhesive force of HepG2 cells to stimulated HUVECs is significantly higher than that of unstimulated control cells, and… More >

  • Open Access

    REVIEW

    Biophysical approaches for studying the integrity and function of tight junctions

    S.R.K. Vedula1, T.S. Lim2, P.J. Kausalya3, W. Hunziker3, G. Rajagopal2, C.T. Lim1,4

    Molecular & Cellular Biomechanics, Vol.2, No.3, pp. 105-124, 2005, DOI:10.3970/mcb.2005.002.105

    Abstract Cell-cell adhesion is an extremely important phenomenon as it influences several biologically important processes such as inflammation, cell migration, proliferation, differentiation and even cancer metastasis. Furthermore, proteins involved in cell-cell adhesion are also important from the perspective of facilitating better drug delivery across epithelia. The adhesion forces imparted by proteins involved in cell-cell adhesion have been the focus of research for sometime. However, with the advent of nanotechnological techniques such as the atomic force microscopy (AFM), we can now quantitatively probe these adhesion forces not only at the cellular but also molecular level. Here, we review the structure and function… More >

  • Open Access

    ARTICLE

    Mechanical Response Analysis and Safety Assessment of Shallow-Buried Pipeline under the Influence of Mining

    Zhengzheng Cao1, Yuejin Zhou1,2, Ping Xu1, Jiawei Li1

    CMES-Computer Modeling in Engineering & Sciences, Vol.101, No.5, pp. 351-364, 2014, DOI:10.3970/cmes.2014.101.351

    Abstract In accordance with the influence of underground mining on the deformation and failure of a shallow-buried gas pipeline, the pipe-soil interaction during mining is classified into two stages, namely coordinated deformation stage and partial hanging stage. According to the mechanical characteristics of the buried pipeline in each stage, the models of a) a beam on an elastic foundation, b) an elastic beam under uniform load, and c) a vertical and horizontal bending beam are introduced in a mining subsidence zone to mechanically analyze, respectively a) the pipeline in non-mining subsidence zone, b) the pipeline at the coordinated deformation stage, and… More >

  • Open Access

    ARTICLE

    CFD and Experimental Investigations of Drag Force on Spherical Leak Detector in Pipe Flows at High Reynolds Number

    ShiXu Guo1, Shili Chen1, Xinjing Huang1, Yu Zhang1, Shijiu Jin1

    CMES-Computer Modeling in Engineering & Sciences, Vol.101, No.1, pp. 59-80, 2014, DOI:10.3970/cmes.2014.101.059

    Abstract Spherical leak detectors can detect very tiny leakage in pipelines and have low risk of blockage. In this paper the passing ability of the detector in the vertical segment of a pipe was studied using CFD simulations and experiments. The Reynolds number for the sphere exceeds 104 at the economical velocity range for oil pipelines, and there were few researches related to the hydrodynamic force on the sphere by the pipe flow at high Reynolds number. For sphere with different sizes and density, and at different flow rates, more than 100 3-D steady numerical simulations were carried out. The simulation… More >

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