Zheng Qin1,2,#, Yueyao Zhang3,#, Dongze Liu4,#, Xiaokang Zheng5, Kaibin Wang1,2, Xiao Zhu1,2, Yuanhao Zhang1,2, Kexin Xu1,2, Changying Li1,2, Lijuan Kang1,2, Lili Wang1,2, Haitao Wang1,2,*
Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2025.073455
- 23 March 2026
Abstract Objective: Prostate cancer is the second most common fatal cancer in men. Identifying new biological therapeutic targets is crucial to effectively improve the prognosis of prostate cancer patients. Ovarian tumor family deubiquitinase 4 (OTUD4) is a member of the ovarian tumor-associated protease domain (OTUDs) family. Although previous studies have shown that the expression and function of OTUD4 vary across different tumors, its role in prostate cancer remains unknown. The aim of this study is to explore new therapeutic targets and diagnostic markers for prostate cancer and investigate their mechanisms of action. Methods: Cell culture, Cell… More >