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  • Open Access

    ARTICLE

    Design of Orthopedic Plates and Its Modification Based on Feature

    He Kunjin1,2, Zou Zeyu1, Zhang Rongli1

    Molecular & Cellular Biomechanics, Vol.12, No.4, pp. 265-286, 2015, DOI:10.32604/mcb.2015.012.263

    Abstract To quickly construct the orthopedic plates and to conveniently edit it, a novel method for designing the plates is put forward based on feature idea and parameterization. Firstly, attached to the existing or repaired bone model, the region of interest (ROI) is selected as the abutted surface of orthopedic plate, and the ROI is reconstructed to form a CAD surface. Secondly, the CAD surface is to be defined as a surface feature (SF) and then some semantic parameters are configured for it. Lastly, the plate body is constructed through thickening, and some higher parameters are defined for it so as… More >

  • Open Access

    ARTICLE

    Cytoplasmic Motion Induced by Cytoskeleton Stretching and Its Effect on Cell Mechanics

    T. Zhang*

    Molecular & Cellular Biomechanics, Vol.8, No.3, pp. 169-194, 2011, DOI:10.3970/mcb.2011.008.169

    Abstract Cytoplasmic motion assumed as a steady state laminar flow induced by cytoskeleton stretching in a cell is determined and its effect on the mechanical behavior of the cell under externally applied forces is demonstrated. Non-Newtonian fluid is assumed for the multiphase cytoplasmic fluid and the analytical velocity field around the macromolecular chain is obtained by solving the reduced nonlinear momentum equation using homotopy technique. The entropy generation by the fluid internal friction is calculated and incorporated into the entropic elasticity based 8-chain constitutive relations. Numerical examples showed strengthening behavior of cells in response to externally applied mechanical stimuli. The spatial… More >

  • Open Access

    ARTICLE

    Digital control circuitry of cancer cell and its apoptosis

    R. M. Ardito Marretta*, G. Barbaraci

    Molecular & Cellular Biomechanics, Vol.6, No.3, pp. 175-190, 2009, DOI:10.3970/mcb.2009.006.175

    Abstract This study, through a typical aerospace systems architecture, suggests an engineering design of a human cancer cell circuitry in which a digital optimal control matrix is assigned to repair the DNA damage level and/or to trigger its apoptosis.
    Here, the conceived machinery is proposed taking into account the state of the art in cancer investigation. However, it could be further generalized. The most recent studies on cancer pathologies give a predominant role to the oncosuppressor protein p53 and its antagonist, the oncogene Mdm2.
    Experimental and theoretical approaches are in agreement in deducing a “digital” response of the p53 when genomic… More >

  • Open Access

    ARTICLE

    Heterogeneous Memristive Models Design and Its Application in Information Security

    Shaojiang Zhong1, *

    CMC-Computers, Materials & Continua, Vol.60, No.2, pp. 465-479, 2019, DOI:10.32604/cmc.2019.05853

    Abstract Based on the three-dimensional classic Chua circuit, a nonlinear circuit containing two flux-control memristors is designed. Due to the difference in the design of the characteristic equation of the two magnetron memristors, their position form a symmetrical structure with respect to the capacitor. The existence of chaotic properties is proved by analyzing the stability of the system, including Lyapunov exponent, equilibrium point, eigenvalue, Poincare map, power spectrum, bifurcation diagram et al. Theoretical analysis and numerical calculation show that this heterogeneous memristive model is a hyperchaotic five-dimensional nonlinear dynamical system and has a strong chaotic behavior. Then, the memristive system is… More >

  • Open Access

    ARTICLE

    Knowledge Composition and Its Influence on New Product Development Performance in the Big Data Environment

    Chuanrong Wu1,*, Veronika Lee1, Mark E. McMurtrey2

    CMC-Computers, Materials & Continua, Vol.60, No.1, pp. 365-378, 2019, DOI:10.32604/cmc.2019.06949

    Abstract Product innovation is regarded as a primary means for enterprises to maintain their competitive advantage. Knowledge transfer is a major way that enterprises access knowledge from the external environment for new product innovation. Knowledge transfer may face the risk of infringement of the intellectual property rights of other enterprises and the termination of licensing agreements by the knowledge source. Enterprises must develop independent innovation knowledge at the same time they profit from knowledge transfers. Therefore, new product development by an enterprise usually consists of three types of new knowledge: big data knowledge transferred from big data knowledge providers, private knowledge… More >

  • Open Access

    ARTICLE

    The Algorithm of Chemical Species Analysis for Ab Intio Molecular Dynamics Simulations and Its Application

    Zhiyi Han1, Yugai Huang2,3, Xiaoqiang Xie1, Ying Mei1, Bin Gu1,*

    CMC-Computers, Materials & Continua, Vol.59, No.3, pp. 995-1003, 2019, DOI:10.32604/cmc.2019.02181

    Abstract In ab initio molecular dynamics (AIMD) simulations of chemical reactions, it is important but difficult to identify the chemical species in the trajectory automatically and quickly. In this paper, based on the chemical graph theory, an algorithm for molecular species identification, according to the molecular coordinates and empirical bond length database, is presented. As an example, the chemical species in condensed glycine at room temperature are investigated with our algorithm in detail. The chemical species, including canonical and zwitterionic glycine, their protonated and de-protonated states, and the free protons, are all identified, counted and recorded correctly. Potential applications and further… More >

  • Open Access

    ARTICLE

    Transient Response in Cross-Ply Laminated Cylinders and Its Application to Reconstruction of Elastic Constants

    X. Han1,2,3, G. R. Liu1,2, G. Y. Li 1

    CMC-Computers, Materials & Continua, Vol.1, No.1, pp. 39-50, 2004, DOI:10.3970/cmc.2004.001.039

    Abstract An efficient hybrid numerical method is presented for investigating transient response of cross-ply laminated axisymmetric cylinders subjected to an impact load. In this hybrid numerical method, the laminated cylinder is divided into layered cylindrical elements in the thickness direction. The Hamilton principle is used to develop governing equations of the structure. The displacement response is determined by employing the Fourier transformations and the modal analysis. Numerical examples for analyzing transient waves have been provided in axisymmetric laminated cylindrical structures, both for thin cylindrical shells and thick cylinders.
    A computational inverse technique is also presented for reconstructing elastic constants of… More >

  • Open Access

    ARTICLE

    Surface Electric Gibbs Free Energy and Its Effect on the Electromechanical Behavior of Nano-Dielectrics

    Ying Xu1, Shengping Shen1,2

    CMC-Computers, Materials & Continua, Vol.28, No.1, pp. 81-96, 2012, DOI:10.3970/cmc.2012.028.081

    Abstract This paper considers the surface effect through the surface and bulk electric Gibbs free energy. The analytical expressions are derived for the effective elastic, dielectric and piezoelectric modulus for nano-structural elements in electromechanical coupling problems. Numerical examples for PZT are given to illustrate the size effects on the electromechanical properties of nano-particles, nano-wires and nano-films quantitatively. The solution shows that the electromechanical properties of piezoelectric nano-material are size-dependent but the size effects on the elastic property and dielectric property are different. More >

  • Open Access

    ARTICLE

    FEM Modeling of the Interface Strength and Its Effect on the Deformation Behaviour of Aluminum Cenosphere Syntactic Foam

    Raghvendra Khedle1, D.P.Mondal2, S.N.Verma1, Sanjay Panthi2

    CMC-Computers, Materials & Continua, Vol.27, No.3, pp. 211-230, 2012, DOI:10.3970/cmc.2011.027.211

    Abstract The interface in aluminum cenosphere syntactic foam (ACSF) is modeled using FEM to study its deformation behaviour as a function of interface characteristics such as interface stiffness and thickness. The interface is modeled as a thin layer of object. The effective modulus and stress of ACSF examined when it contain 50% cenosphere by volume. In this study, the shell wall thickness of cenosphere is fixed at 1µm. The width of the interface varies from 0.2% to 0.6% of cenosphere volume fraction. The interface strength and modulus varies in the range of 10 to 50% of the matrix alloy. The values… More >

  • Open Access

    ARTICLE

    A Modified Prandtl-Ishlinskii Model and its Applications to Inverse Control of Piezoelectric Actuators

    J. H. Qiu1,2, H. Jiang1, H. L. Ji1, N. Hu3

    CMC-Computers, Materials & Continua, Vol.26, No.1, pp. 1-18, 2011, DOI:10.3970/cmc.2011.026.001

    Abstract Piezoelectric actuators based motion-producing devices are widely used in precision machining, deformable mirrors, micropumps and piezoelectric injection systems. However, because of their hysteresis nonlinear property, the piezoelectric actuators can not provide absolutely precise displacements. To solve this problem, researchers applied inverse control method to compensate the nonlinearity of piezoelectric actuators, and the inverse models are mainly based on traditional hysteresis models such as the Preiasch model or Prandtl-Ishlinskii model. In this paper, a new approach for inverse control of piezoelectric actuators is presented. The new method utilize a modified Prandtl-Ishlinskii model which is based on a combination of two asymmetric… More >

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