Jesús Rodrigo-Comino^1,*, María Teresa González-Moreno¹, Lucía Moreno-Cuenca¹, Laura Cambronero-Ruiz¹, Clemente Irigaray², Francisco Serrano Bernardo³, Víctor Hugo Durán Zuazo⁴, Jesús Fernández-Gálvez⁵, Andrés Caballero-Calvo⁵, Víctor Rodríguez-Galiano⁶

Revue Internationale de Géomatique, Vol.35, pp. 333-349, 2026, DOI:10.32604/rig.2026.081503 - 11 June 2026

Abstract Soil degradation in Mediterranean agricultural systems is strongly conditioned by topography, water redistribution and solar exposure, factors that can be effectively studied using very high-resolution remote sensing. This study evaluates the potential of Unmanned Aerial Vehicle (UAV)-derived geomorphometry combined with machine learning techniques to analyse the spatial variability of the Normalized Difference Vegetation Index (NDVI) as a surface spectral response under post-harvest conditions in a Mediterranean cereal field affected by soil degradation and gully erosion, located near Casabermeja (Málaga, southern Spain). High-resolution RGB and multispectral UAV data were used to generate a Digital Terrain Model… More >

Guoxu Ma, Yonglu Huang, Fan Gong, Jianke Wu, Yi Ding, Ziyang Zhang, Xiaoliang Li, Jian Gao, Tingting Dang, Bowen Zhang^*

BIOCELL, Vol.50, No.6, 2026, DOI:10.32604/biocell.2026.078402 - 09 June 2026

Abstract Objectives: Sciatic nerve injury (SNI) impairs quality of life, and Lycium barbarum polysaccharides (LBP) may exert therapeutic effects via regulating Schwann cell (SC) mitochondrial stability, though the mechanism remains unclear. The study aimed to elucidate the therapeutic mechanisms of LBP in mitigating sciatic nerve injury by protecting Schwann cells via the estrogen receptor 1 (ESR1)/thioredoxin 2 (Trx2) pathway. Methods: An in vitro SNI model was established by inducing RSC96 cells with H₂O₂. Cell counting kit-8 (CCK8) assay, enzyme-linked immunosorbent assay (ELISA), Western blot, reactive oxygen species (ROS) and adenosine triphosphate (ATP) quantification, and mitochondrial membrane potential (MMP) detection were… More >

Desirée Victoria-Montesinos^*, Pablo Barcina-Pérez^*, Ana María García-Muñoz

BIOCELL, Vol.50, No.6, 2026, DOI:10.32604/biocell.2026.077286 - 09 June 2026

Abstract Mitochondrial dysfunction is a central hallmark of metabolic, hepatic, cardiovascular, and neurodegenerative diseases. Dietary polyphenols modulate mitochondrial pathways, but their integrated effects remain poorly appreciated. This narrative review synthesizes preclinical and clinical evidence on four polyphenols (resveratrol, epigallocatechin-3-gallate, quercetin, and oleuropein) and examines their mechanisms in mitochondrial biogenesis, mtDNA protection, and mitophagy. Experimental studies indicate that these compounds activate conserved adaptive pathways, including sirtuin 1 (SIRT1) and peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α), AMP-activated protein kinase (AMPK), and PTEN-induced kinase 1 (PINK1) with Parkin, therapy enhancing mitochondrial biogenesis, reducing oxidative stress, and promoting More >

Moo Hyun Kim¹, Yongdae Yoon², Chang Wan Kim¹, Jun-Won Lee³, Bhupendra Regmi², Saher Fatima², Moon Young Kim^2,3, Soon Koo Baik^2,3, Pil Young Jung^1,*, Young Woo Eom^2,*

BIOCELL, Vol.50, No.6, 2026, DOI:10.32604/biocell.2026.076364 - 09 June 2026

Abstract Background: Although transforming growth factor-β (TGF-β) drives hepatic stellate cell activation and fibrogenesis, the mechanisms by which 12-O-tetradecanoylphorbol-13-acetate (TPA) modulates these processes in TGF-β1-activated hepatic stellate cells remain to be determined. Therefore, we investigated whether TPA alleviates fibrosis in TGF-β1-treated hepatic stellate cells and regulates both canonical and non-canonical pathways. Further, we assessed whether inhibitors of these pathways similarly affect proliferation and fibrosis in LX-2 cells. Methods: LX-2 hepatic stellate cells were used as the experimental model. Cells were treated with TPA, TGF-β, or TGF-β plus TPA, and Yes-associated protein (YAP) and protein kinase B (PKB;… More >

Junming Yan, Boran Xiong, Yingjie Zhu^*

BIOCELL, Vol.50, No.6, 2026, DOI:10.32604/biocell.2026.075319 - 09 June 2026

Abstract Objective: Neural stem cells (NSCs) are essential for replenishing nerve cells, providing neuroprotection, and repairing damaged brain function, while mitophagy is critical for maintaining NSCs’ homeostasis. The study investigated whether pyruvate kinase M2 (PKM2) regulates NSCs’ proliferation and differentiation by modulating mitophagy. Method: This study established a model of excessive autophagy in neural stem cell mitochondria induced by cobalt chloride (CoCl₂) and used plasmid transfection technology to knock down PKM2 expression, examining its effects on NSCs proliferation and differentiation. Additionally, potential mechanisms were explored by overexpressing phosphatase and tensin homolog-induced putative kinase 1 (PINK1) and adding the… More > Graphic Abstract

S. D. Al-Sahafi^*

Chalcogenide Letters, Vol.23, No.5, 2026, DOI:10.32604/cl.2026.082364 - 02 June 2026

Abstract In this study, a lead-free double perovskite solar cell structure based on Cs₂BiAgI₆ was simulated and optimized to enhance photovoltaic performance. The device architecture follows the configuration: ITO/PCBM/C₆₀/Cs₂BiAgI₆/CdTe/Au. The thicknesses of the electron transport layer (ETL), absorber layer, and hole transport layer (HTL) are systematically optimized to evaluate their impact on key performance parameters. The results indicate that optimal performance is achieved with 600 nm thicknesses for all ETLs and HTL, and 2 μm for the Cs₂BiAgl₆ absorber. Under these conditions, the device exhibits a short-circuit current density of 23.23 mA/cm², an open-circuit voltage of 1.08 V, More >

Megabi Adane Yizengaw^1,*, Alehegn Atalay Birlie¹, Tamerat Tesfaye², Rajan Katrikan¹, Eldana Bizuneh Cheklie¹, Zelalem Girma¹

Journal of Renewable Materials, Vol.14, No.5, 2026, DOI:10.32604/jrm.2025.02025-0175 - 28 May 2026

Abstract Grape by-product of the wine industry, rich in polyphenols, tannins, lignin, and natural waxes, the chemical constituents grape skins 45%–55%, seeds 25%–35%, and stems or stalks 25%–35% weight of grape provide intrinsic cross-linking, mechanical reinforcement, antioxidant activity, and water resistance, closely replicating the effects of conventional vegetable tanning without using toxic chemicals. This review comprehensively examines current eco-friendly extraction methods to isolate bioactive compounds, as well as fiber modification techniques to improve polymer compatibility. Composite fabrication involves blending processed grape waste fibers with bio-based polymers and renewable plasticizers to produce materials exhibiting competitive tensile strength,… More >

Zhiying Lin¹, Boju Deng¹, Qianqian Zhang¹, Jingming Chen², Xinqiang Ye³, Yuling Lan¹, Jiuping Rao^1,*, Mizi Fan⁴, Weigang Zhao^1,*

Journal of Renewable Materials, Vol.14, No.5, 2026, DOI:10.32604/jrm.2025.02025-0096 - 28 May 2026

Abstract Bio-derived carbon cryogels have garnered significant interest as promising electrode materials for supercapacitors due to their high specific surface area (SSA), hierarchical porosity, and eco-friendly synthesis methods. In this study, a tannin-modified phenolic hydrogel was synthesized using a sustainable tannin–phenol precursor system and subsequently subjected to three distinct drying methods-freeze-drying (FD), supercritical drying (SCD), and ambient pressure drying (APD)-to systematically evaluate their influence on structural integrity, porosity, and electrochemical behavior. Among these, the sample obtained via freeze-drying (TPUF-FD) maintained the most intact porous network, minimizing structural collapse during sublimation of ice under vacuum. This preservation… More > Graphic Abstract

Xiaojian You¹, Zhen Sun¹, Lei Zhang¹, Weikun Qian¹, Cong Wang¹, Weigang Pang¹, Hongming Li¹, Yingshuang Cui¹, Chen Chen¹, Yue Wang¹, Xiao Wu^2,*

FDMP-Fluid Dynamics & Materials Processing, Vol.22, No.5, 2026, DOI:10.32604/fdmp.2026.081350 - 27 May 2026

Abstract Slug flow poses significant dynamic challenges in multiphase pipeline transport, particularly in complex offshore and Floating Liquefied Natural Gas systems, where conventional one- and two-dimensional models fail to capture the intricate three-dimensional interfacial topologies and transient liquid-film dynamics. To overcome this limitation, the present study develops a three-dimensional transient numerical model based on the coupled level-set and volume-of-fluid (CLSVOF) method within a large eddy simulation (LES) framework, and validates it against high-frequency measurements obtained from a double parallel conductance probe experimental platform. The proposed model successfully resolves phase velocity slip and interfacial morphological evolution, predicting More >

Xiaoshan Wang¹, Qiang Cui¹, Lei Pu^2,*

FDMP-Fluid Dynamics & Materials Processing, Vol.22, No.5, 2026, DOI:10.32604/fdmp.2026.081184 - 27 May 2026

Abstract The passability (transport behavior) of while-drilling lost circulation materials (LCMs) through directional tools is strongly influenced by material composition and particle characteristics. In this study, a coupled computational fluid dynamics–discrete element method (CFD–DEM) model is developed to systematically evaluate the effects of particle size distribution, concentration, morphology, and fiber inclusion on LCM transport behavior. Visualization experiments conducted using a transparent screen section demonstrate good agreement with the simulated pressure-drop evolution, supporting the validity of the model. The results reveal that increasing particle size from 1.2–1.6 mm to above 2.8 mm shifts the system from a More > Graphic Abstract