QIAO ZHOU^2,3,4, JIAN LIU^1,2,*, LING XIN¹, YANYAN FANG^1,2, LEI WAN^1,2, DAN HUANG^1,2, JIANTING WEN^1,2

BIOCELL, Vol.47, No.7, pp. 1623-1643, 2023, DOI:10.32604/biocell.2023.028331

Abstract Objective: On the basis of data mining, systematic pharmacology, molecular docking, and experiment validation, the oxidative-inflammatory molecular targets of Coicis Semen in the therapy of osteoarthritis (OA) were explored. Methods: The association rule analysis was effectively applied to highlight the correlation between Coicis Semen and oxidative inflammation indices. The random walk model was subsequently used to evaluate the clinical efficacy of Coicis Semen. Network pharmacology was used to predict network targets. The binding affinity of the active ingredient in Coicis Semen to the key target of OA was also successfully predicted. Results: Coicis Semen showed a significant reduction in oxidative-inflammatory indicators… More >

F.C.C. Almeida^a , P.M. da Silva^b,c, M.N.C. Coelho Pinheiro^a,d,*

Frontiers in Heat and Mass Transfer, Vol.12, pp. 1-9, 2019, DOI:10.5098/hmt.12.16

Abstract In the last decades, polymeric systems were essayed and applied successfully as vehicles for transdermal delivery devices of active principles. Applications in contraception, pain control, and smoking cessation are already frequent. A crucial aspect in the development of new formulations is the maintenance of the therapeutic drug concentration range for long periods. Recognizing this topic as interesting and challenging, simple models to describe drug release from a transdermal device were developed with the purpose to perform a parametric sensitivity analysis. Assuming drug diffusion within the polymeric delivery system as the dominant mechanism the models were More >

Musaed Alrashidi^*

Computer Systems Science and Engineering, Vol.47, No.1, pp. 491-513, 2023, DOI:10.32604/csse.2023.038628

Abstract Statistical distributions are used to model wind speed, and the two-parameters Weibull distribution has proven its effectiveness at characterizing wind speed. Accurate estimation of Weibull parameters, the scale (c) and shape (k), is crucial in describing the actual wind speed data and evaluating the wind energy potential. Therefore, this study compares the most common conventional numerical (CN) estimation methods and the recent intelligent optimization algorithms (IOA) to show how precise estimation of c and k affects the wind energy resource assessments. In addition, this study conducts technical and economic feasibility studies for five sites in the northern… More >

Anne Ruas, Ha Pham, Laura Pinson

Revue Internationale de Géomatique, Vol.29, No.2, pp. 185-205, 2019, DOI:10.3166/rig.2019.00081

Abstract De nombreuses études et recherches visent à mieux connaitre les phénomènes de type pollution ou météo. Les champs de valeur représentant ces phénomènes peuvent être visualisés sur des outils de visualisation scientifiques qui ne disposent pas de la richesse de symbolisation propre aux SIGs, notamment pour le géoréférencement et pour la représentation des objets vectoriels décrivant l’espace support. La représentation sous forme raster sur SIG est possible mais limitée. Pourtant au niveau scientifique il est important de pouvoir co-visualiser les champs dans leur contexte géographique pour mieux les analyser et faire des hypothèses sur les… More >

D. Peyrat-Apicella, Y. Chemrouk

Psycho-Oncologie, Vol.16, No.4, pp. 381-387, 2022, DOI:10.3166/pson-2022-0214

Abstract Objectif : La récente loi Claeys-Leonetti de 2016 reconnaît le droit du patient à une sédation profonde et continue jusqu’au décès (SPCJD) si ce dernier en fait la demande. Au quotidien, comment les équipes soignantes s’approprient cette nouvelle possibilité et s’adaptent à ces situations de fin de vie spécifiques ?
Méthode : Nous avons mené des entretiens semi-directifs avec six soignants volontaires de chaque corps de métier (deux médecins, deux infirmier.ère.s et deux aides-soignantes) dans un service d’oncologie médicale et de radiothérapie. Les entretiens ont été analysés selon une méthode d’analyse de contenu thématique, afin de rendre… More >

Tareq Alhmiedat^1,2,*, Ashraf M. Marei^1,2, Saleh Albelwi^1,2, Anas Bushnag², Wassim Messoudi², Abdelrahman Osman Elfaki^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.3, pp. 2321-2344, 2023, DOI:10.32604/cmes.2023.025641

Abstract Agricultural projects in different parts of the world depend on underground water wells. Recently, there have been many unfortunate incidents in which children have died in abandoned underground wells. Providing topographical information for these wells is a prerequisite to protecting people from the dangers of falling into them, especially since most of these wells become buried over time. Many solutions have been developed recently, most with the aim of exploring these well areas. However, these systems suffer from several limitations, including high complexity, large size, or inefficiency. This paper focuses on the development of a… More >

Biqian Cheng¹, Lulu Chen², Bo Yang^3,*

International Journal of Mental Health Promotion, Vol.25, No.4, pp. 595-611, 2023, DOI:10.32604/ijmhp.2023.027321

Abstract In order to explore the criminal psychological mechanism of burglars, this study adopts the qualitative research method of grounded theory to conduct in-depth interviews with 41 burglars in two prisons in Jiangxi Province, China. Nvivo 11.0 was used to code-construct and qualitatively analyze the interview content in order to refine the influencing factors and psychological evolution process of burglary behavior. The findings revealed that (1) burglary risk factors include burglary cognition, burglary motivation, burglary decision-making, delinquent peers, burglary opportunity, and incomplete reformation. (2) There are three stages in the psychological evolution process of burglars: cognitive More > Graphic Abstract

Pavel Trojovský^1,*, Mohammad Dehghani¹, Eva Trojovská¹, Eva Milkova²

CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.2, pp. 1527-1573, 2023, DOI:10.32604/cmes.2023.025908

Abstract In this paper, based on the concept of the NFL theorem, that there is no unique algorithm that has the best performance for all optimization problems, a new human-based metaheuristic algorithm called Language Education Optimization (LEO) is introduced, which is used to solve optimization problems. LEO is inspired by the foreign language education process in which a language teacher trains the students of language schools in the desired language skills and rules. LEO is mathematically modeled in three phases: (i) students selecting their teacher, (ii) students learning from each other, and (iii) individual practice, considering… More > Graphic Abstract

Saeed Ahmed Magsi^1,2,*, Mohd Haris Bin Md Khir¹, Illani Bt Mohd Nawi¹, Muath Al Hasan³, Zaka Ullah³, Fasih Ullah Khan⁴, Abdul Saboor⁵, Muhammad Aadil Siddiqui^1,2

CMC-Computers, Materials & Continua, Vol.75, No.1, pp. 845-862, 2023, DOI:10.32604/cmc.2023.033636

Abstract Long Range Wide Area Network (LoRaWAN) in the Internet of Things (IoT) domain has been the subject of interest for researchers. There is an increasing demand to localize these IoT devices using LoRaWAN due to the quickly growing number of IoT devices. LoRaWAN is well suited to support localization applications in IoTs due to its low power consumption and long range. Multiple approaches have been proposed to solve the localization problem using LoRaWAN. The Expected Signal Power (ESP) based trilateration algorithm has the significant potential for localization because ESP can identify the signal’s energy below… More >

Grégory Ninot^1,2,*, Estelle Guerdoux^1,2, François Carbonnel¹, Kerstin Faravel², Ludovic Ismael¹, Fanny Leenhardt², Béatrice Lognos¹, Caroline Perrier², Laurent Philibert², Boris Tronc¹, Marie Viala²

Oncologie, Vol.24, No.4, pp. 605-612, 2022, DOI:10.32604/oncologie.2022.024558

Abstract Une étude rétrospective observationnelle réalisée aux États-Unis montre une réduction de la survie de patients traités pour un cancer du sein, de la prostate, du poumon et colorectal en cas de déclaration d’usage de thérapies complémentaires (TC). Nous avons voulu vérifier ce résultat auprès d’une population française de 636 patients diagnostiqués des mêmes types de cancers et traités consécutivement par chimiothérapie orale dans un établissement hospitalier durant trois ans. Un entretien par un pharmacien en amont de l’administration d’une chimiothérapie orale a permis d’identifier les TC utilisées par les patients. Nous avons comparé la survie More >