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  • Open Access

    ARTICLE

    Emotion Exploration in Autistic Children as an Early Biomarker through R-CNN

    S. P. Abirami1,*, G. Kousalya1, R. Karthick2

    Intelligent Automation & Soft Computing, Vol.35, No.1, pp. 595-607, 2023, DOI:10.32604/iasc.2023.027562

    Abstract Autism Spectrum Disorder (ASD) is found to be a major concern among various occupational therapists. The foremost challenge of this neurodevelopmental disorder lies in the fact of analyzing and exploring various symptoms of the children at their early stage of development. Such early identification could prop up the therapists and clinicians to provide proper assistive support to make the children lead an independent life. Facial expressions and emotions perceived by the children could contribute to such early intervention of autism. In this regard, the paper implements in identifying basic facial expression and exploring their emotions upon a time-variant factor. The… More >

  • Open Access

    ARTICLE

    An Exploratory Investigation of Difficulties in Applying Functional Behavior Assessment and Implementing Behavioral Intervention Plans in ADHD Programs in Saudi Arabia

    Abdulrahman Abdullah Abaoud*

    International Journal of Mental Health Promotion, Vol.24, No.4, pp. 595-601, 2022, DOI:10.32604/ijmhp.2022.021286

    Abstract Functional behavior assessment (FBA) and behavioral intervention plans (BIPs) can be effective for students with attention deficit hyperactivity disorder (ADHD); however, teachers may face difficulties when implementing FBA procedures and, in turn, BIPs because of lack of time, insufficient training, and multiplicity of beliefs. Thus, it is important to identify the difficulties teachers may face and the obstacles that can deter them from implementing intervention plans. This is a worthwhile endeavor because nearly all classrooms will have students with behavioral problems who will benefit from specifically designed educational interventions. This study aimed to identify the difficulties in applying FBA and… More >

  • Open Access

    ARTICLE

    Two-Stage High-Efficiency Encryption Key Update Scheme for LoRaWAN Based IoT Environment

    Kun-Lin Tsai1,2,*, Li-Woei Chen3, Fang-Yie Leu4,5, Chuan-Tian Wu1

    CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 547-562, 2022, DOI:10.32604/cmc.2022.026557

    Abstract Secure data communication is an essential requirement for an Internet of Things (IoT) system. Especially in Industrial Internet of Things (IIoT) and Internet of Medical Things (IoMT) systems, when important data are hacked, it may induce property loss or life hazard. Even though many IoT-related communication protocols are equipped with secure policies, they still have some security weaknesses in their IoT systems. LoRaWAN is one of the low power wide-area network protocols, and it adopts Advanced Encryption Standard (AES) to provide message integrity and confidentiality. However, LoRaWAN's encryption key update scheme can be further improved. In this paper, a Two-stage… More >

  • Open Access

    ARTICLE

    Effect of Lycopus lucidus Turcz. supplementation on gut microflora and short chain fatty acid composition in Crj: CD-1 mice

    EUN NA1, SUN YOUNG LIM2,*

    BIOCELL, Vol.46, No.9, pp. 2101-2109, 2022, DOI:10.32604/biocell.2022.019807

    Abstract We investigated the diversity and composition of microflora in feces of Lycopus lucidus Turcz.-fed mice. In addition, we evaluated the production of major cytokines (Interleukin-6 and -10) which are related to inflammation and fatty acid composition of several tissues. 16S ribosomal DNA sequencing-based microbiome taxonomic profiling analysis was performed utilizing the EzBioCloud data base. Male mice fed on L. lucidus showed a significantly reduced number of lactic acid bacteria and coliform in the feces compared with the control group (p < 0.05). 16S rDNA sequencing analysis of fecal samples showed that L. lucidus supplementation decreased the community of harmful microflora… More >

  • Open Access

    ARTICLE

    Age-Related Alterations in DNA Methylation and APETALA2 (AP2) Levels in Herbaceous Peony (Paeonia lactiflora Pall.)

    Yanqing Wu1,2, Jiao Liu1, Yuhan Tang2, Daqiu Zhao2, Jun Tao1,2,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.9, pp. 2005-2016, 2022, DOI:10.32604/phyton.2022.021062

    Abstract The ornamental and commercial values of herbaceous peony (Paeonia lactiflora Pall.) are directly related to its flower pattern. However, the molecular mechanisms underlying the type formation of P. lactiflora flowers have not been studied in great detail. Previous studies identified, using integrated multipleomics analysis, revealed that APETALA2 (AP2) is an important candidate gene that modulates type formation of P. lactiflora flowers. To further reveal the expression mechanism of AP2 in P. lactiflora petals, we examined the profile of AP2 expression in the inner and outer petals of ‘ZiFengyu’ at various developmental stages using qRT-PCR and BSP+Miseq methylation analysis. Based on… More >

  • Open Access

    ARTICLE

    Effect of Paclobutrazol Application on Plant Growth and Flower Quality in Herbaceous Peony

    Yanqing Wu1,2, Jiao Liu1, Daqiu Zhao2, Jun Tao1,2,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.9, pp. 2017-2032, 2022, DOI:10.32604/phyton.2022.020643

    Abstract Herbaceous peony (Paeonia lactiflora Pall.) is an important ornamental plant worldwide. In its natural state, P. lactiflora often manifests traits like rapidly elongating internodal growth, loose plant types, and soft inflorescence stems. However, very little has been known about the measures for controlling these traits. This study investigated the effect of applying paclobutrazol (PBZ) on the plant growth and flower quality in P. lactiflora. The results indicated that PBZ application reduced the plant height (8.05%), plant crown width (14.72%), and leaf area (10.90%), but increased the leaf thickness (18.18%) and stem diameter (over 11%) in P. lactiflora. Meanwhile, PBZ application… More >

  • Open Access

    ARTICLE

    Changes in Florets’ Vertical Direction within Inflorescence Affects Pollinator Behavior, and Fitness in Trifolium repens

    Qinzheng Hou#, Wenjuan Shao#, Nurbiye Ehmet#, Taihong Wang, Yifan Xu, Kun Sun*

    Phyton-International Journal of Experimental Botany, Vol.91, No.8, pp. 1617-1628, 2022, DOI:10.32604/phyton.2022.020768

    Abstract Ecological interactions between flowers and pollinators greatly affect the reproductive success. To facilitate these interactions, many flowers are known to display their attractive qualities, such as scent emission, flower rewards and floral vertical direction, in a rhythmic fashion. However, less is known about how plants regulate the relationship between these flower traits to adapt to pollinator visiting behavior and increase reproduction success. Here we investigated the adaptive significance of the flower bending from erect to downward in Trifolium repens. We observed the flowering dynamic characteristics (changes of vertical direction of florets, flowering number, pollen grain numbers, pollen viability and stigma… More >

  • Open Access

    ARTICLE

    Exploration of Combinational Therapeutic Strategies for HCC Based on TCGA HCC Database

    Dong Yan1,#, Chunxiao Li2,#, Yantong Zhou2, Xue Yan1, Weihua Zhi1, Haili Qian2,*, Yue Han1,*

    Oncologie, Vol.24, No.1, pp. 101-111, 2022, DOI:10.32604/oncologie.2022.020357

    Abstract Hepatocellular carcinoma (HCC) is one of the most deadly types of cancer. Sorafenib is currently the only available first-line molecular targeted drug approved by the FDA for HCC. However, primary and secondary resistance is often encountered with treatment with sorafenib. Genomic alterations found in HCC represent potential targets to develop new drugs or new combinational strategies against this type of cancer. Here we analyzed genomic alterations from the TCGA database of HCC samples and the corresponding targeted drugs available to the clinic to identify candidate drugs that might hold promise when used in combination with sorafenib. Our results revealed that… More >

  • Open Access

    ARTICLE

    Optimized LSTM with Dimensionality Reduction Based Gene Expression Data Classification

    S. Jacophine Susmi*

    Intelligent Automation & Soft Computing, Vol.33, No.2, pp. 1139-1152, 2022, DOI:10.32604/iasc.2022.023865

    Abstract The classification of cancer subtypes is substantial for the diagnosis and treatment of cancer. However, the gene expression data used for cancer subtype classification are high dimensional in nature and small in sample size. In this paper, an efficient dimensionality reduction with optimized long short term memory, algorithm (OLSTM) is used for gene expression data classification. The main three stages of the proposed method are explicitly pre-processing, dimensional reduction, and gene expression data classification. In the pre-processing method, the missing values and redundant values are removed for high-quality data. Following, the dimensional reduction is done by orthogonal locality preserving projections… More >

  • Open Access

    ARTICLE

    Efficient Heuristic for Optimal MILP-LoRa Adaptive Resource Allocation for Aquaculture

    M. Iniyan Arasu1,*, S. Subha Rani1, G. Raswin Geoffery2

    Intelligent Automation & Soft Computing, Vol.33, No.2, pp. 729-742, 2022, DOI:10.32604/iasc.2022.021973

    Abstract LoRa is well-known for its extensive communication range, inexpensive efficiency, and reduced or less power consumption in end devices. End-device energy consumption in LoRa networks is ludicrous because some end-devices use massive dissemination variables to reach the remote doorway. Furthermore, the batteries in these end devices deplete very quickly, reducing network life significantly. To address this issue, an optimal mixed-integer linear programming long-range technique (OMILP-LoRa) was used in this study. The primary goal of this research is to enable adaptive resource allocation using the unique OMILP-LoRa protocol. The ACCURATE heuristic and the OMILP model for LoRaWAN resource allocation are presented… More >

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