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  • Open Access

    ARTICLE

    Impact of Social Determinants of Health on Self-Perceived Resilience: An Exploratory Study of Two Cohorts of Adults with Congenital Heart Disease

    Albert Osom1, Krysta S. Barton2, Katie Sexton3,4, Lyndia Brumback1, Joyce P. Yi-Frazier4, Abby R. Rosenberg5,6, Ruth Engelberg7, Jill M. Steiner8,*

    Congenital Heart Disease, Vol.19, No.1, pp. 33-48, 2024, DOI:10.32604/chd.2024.046656

    Abstract Social determinants of health (SDOH) affect quality of life. We investigated SDOH impacts on self-perceived resilience among people with adult congenital heart disease (ACHD). Secondary analysis of data from two complementary studies: a survey study conducted May 2021–June 2022 and a qualitative study conducted June 2020–August 2021. Resilience was assessed through CD-RISC10 score (range 0–40, higher scores reflect greater self-perceived resilience) and interview responses. Sociodemographic and SDOH (education, employment, living situation, monetary stability, financial dependency, area deprivation index) data were collected by healthcare record review and self-report. We used linear regression with robust standard errors to analyze survey data and… More > Graphic Abstract

    Impact of Social Determinants of Health on Self-Perceived Resilience: An Exploratory Study of Two Cohorts of Adults with Congenital Heart Disease

  • Open Access

    ARTICLE

    Fine-Tuned Extra Tree Classifier for Thermal Comfort Sensation Prediction

    Ahmad Almadhor1, Chitapong Wechtaisong2,*, Usman Tariq3, Natalia Kryvinska4,*, Abdullah Al Hejaili5, Uzma Ghulam Mohammad6, Mohana Alanazi7

    Computer Systems Science and Engineering, Vol.48, No.1, pp. 199-216, 2024, DOI:10.32604/csse.2023.039546

    Abstract Thermal comfort is an essential component of smart cities that helps to upgrade, analyze, and realize intelligent buildings. It strongly affects human psychological and physiological levels. Residents of buildings suffer stress because of poor thermal comfort. Buildings frequently use Heating, Ventilation, and Air Conditioning (HVAC) systems for temperature control. Better thermal states directly impact people’s productivity and health. This study revealed a human thermal comfort model that makes better predictions of thermal sensation by identifying essential features and employing a tuned Extra Tree classifier, MultiLayer Perceptron (MLP) and Naive Bayes (NB) models. The study employs the ASHRAE RP-884 standard dataset… More >

  • Open Access

    ORIGINAL RESEARCH

    Exploratory Study of Intolerance of Uncertainty and Its Cognitive Processes by the Stroop Task among Parents of a Childhood Cancer Survivor

    Etude exploratoire de l’intolérance à l’incertitude et de ses processus cognitifs par la tâche du Stroop chez les parents d’un enfant en rémission de cancer

    Marie Vander Haegen*, Anne-Marie Etienne

    Psycho-Oncologie, Vol.17, No.4, pp. 257-266, 2023, DOI:10.32604/po.2023.043340

    Abstract Introduction. No study has examined the relationship between the factor of intolerance of uncertainty and its effects on the cognitive processes among parents of a childhood cancer survivor. Intolerance of uncertainty is a central factor in generalized anxiety disorder; an anxiety disorder in which impaired processing of cognitive information in the form of cognitive biases is also observed. The aim of the study was to measure, via a classical Stroop test and an emotional Stroop test, the orientation of selective attention in relation to the uncertainty intolerance factor. Methods. 61 parents of a childhood cancer survivor (aged 4 to 6… More >

  • Open Access

    ARTICLE

    Evaluation of combined detection of nuclear factor erythroid 2-related factor 2 and glutathione peroxidase 4 in primary hepatic carcinoma and preliminary exploration of pathogenesis

    JIE DUAN, AIDONG GU*, WEI CHEN, CHANGHAO CHEN, FANGNAN SONG, FAXI CHEN, FANGFANG JIANG, HUIWEN XING

    BIOCELL, Vol.47, No.12, pp. 2609-2615, 2023, DOI:10.32604/biocell.2023.042472

    Abstract Objective: This study aims to analyze the clinical significance and mechanism of nuclear factor erythroid 2-related factor 2 (NRF2) and glutathione peroxidase 4 (GPX4) in primary hepatic carcinoma (PHC). Methods: The expression of NRF2 and GPX4 in peripheral blood of patients with PHC was determined to analyze the diagnostic value of the two combined for PHC. The prognostic significance of NRF2 and GPX4 was evaluated by 3-year follow-up. Human liver epithelial cells THLE-2 and human hepatocellular carcinoma cells HepG2 were purchased, and the expression of NRF2 and GPX4 in the cells was determined. NRF2 and GPX4 aberrant expression vectors were… More > Graphic Abstract

    Evaluation of combined detection of nuclear factor erythroid 2-related factor 2 and glutathione peroxidase 4 in primary hepatic carcinoma and preliminary exploration of pathogenesis

  • Open Access

    ARTICLE

    A New Exploration of Artificially Induced Spalted Wood of Two Fungi: Hypoxylon and Sistotrema

    Yan Yan, Junpeng Dong, Haibo Hu, Susu Yang, Lin Liu, Lei Qin*

    Journal of Renewable Materials, Vol.11, No.11, pp. 3907-3916, 2023, DOI:10.32604/jrm.2023.028099

    Abstract One strain of Hypoxylon sp. CXM-3 and one strain of Sistotrema brinkmannii CXM-4 were inoculated onto sterilized cherry, poplar, birch, and basswood sheets in a certain shape and incubated at constant temperature and humidity for 4, 8, 12, and 16 weeks, respectively, to analyze whether the grain pattern formed by the zone lines was consistent with the predetermined pattern. The results showed that the zone lines of CXM-3 of Hypoxylon were free, delicate, and soft, with brown lines and black staining, mostly accompanied by black and brown dots, facets, and clusters, while the zone lines of CXM-4 of Sistotrema brinkmanniiMore > Graphic Abstract

    A New Exploration of Artificially Induced Spalted Wood of Two Fungi: <i>Hypoxylon</i> and <i>Sistotrema</i>

  • Open Access

    ARTICLE

    An Effective Runge-Kutta Optimizer Based on Adaptive Population Size and Search Step Size

    Ala Kana, Imtiaz Ahmad*

    CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 3443-3464, 2023, DOI:10.32604/cmc.2023.040775

    Abstract A newly proposed competent population-based optimization algorithm called RUN, which uses the principle of slope variations calculated by applying the Runge Kutta method as the key search mechanism, has gained wider interest in solving optimization problems. However, in high-dimensional problems, the search capabilities, convergence speed, and runtime of RUN deteriorate. This work aims at filling this gap by proposing an improved variant of the RUN algorithm called the Adaptive-RUN. Population size plays a vital role in both runtime efficiency and optimization effectiveness of metaheuristic algorithms. Unlike the original RUN where population size is fixed throughout the search process, Adaptive-RUN automatically… More >

  • Open Access

    REVIEW

    Molecular dynamics-driven exploration of peptides targeting SARS-CoV-2, with special attention on ACE2, S protein, Mpro, and PLpro: A review

    MOHAMAD ZULKEFLEE SABRI1, JOANNA BOJARSKA2, FAI-CHU WONG3,4, TSUN-THAI CHAI3,4,*

    BIOCELL, Vol.47, No.8, pp. 1727-1742, 2023, DOI:10.32604/biocell.2023.029272

    Abstract Molecular dynamics (MD) simulation is a computational technique that analyzes the movement of a system of particles over a given period. MD can provide detailed information about the fluctuations and conformational changes of biomolecules at the atomic level over time. In recent years, MD has been widely applied to the discovery of peptides and peptide-like molecules that may serve as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibitors. This review summarizes recent advances in such explorations, focusing on four protein targets: angiotensin-converting enzyme 2 (ACE2), spike protein (S protein), main protease (Mpro), and papain-like protease (PLpro). These four proteins are… More > Graphic Abstract

    Molecular dynamics-driven exploration of peptides targeting SARS-CoV-2, with special attention on ACE2, S protein, M<sup>pro</sup>, and PL<sup>pro</sup>: A review

  • Open Access

    ARTICLE

    Physicochemical Properties of Combustion Ashes of Some Trees (Urban Pruning) Present in the Neotropical Region

    John Freddy Gelves-Díaz1,*, Ludovic Dorkis2, Richard Monroy-Sepúlveda1, Sandra Rozo-Rincón1, Yebrail Alexis Romero-Arcos1

    Journal of Renewable Materials, Vol.11, No.10, pp. 3769-3787, 2023, DOI:10.32604/jrm.2023.029270

    Abstract Secondary lignocellulosic biomass has proved to be useful as an energy source through its oxidation by means of combustion processes. In accordance with the above, in this paper, we wanted to study the ash from urban pruning residues that are generated in cities in the Neotropics. Species such as Licania tomentosa, Azadirachta indica, Ficus benjamina, Terminalia catappa, Leucaena leucocephala, Prosopis juliflora and Pithecellobium dulce were selected because they have been previously studied and showed potential for thermal energy generation. These materials were calcined in an oxidizing atmosphere and characterized by X-ray diffraction and fluorescence, scanning electron microscopy with microchemistry, BET… More > Graphic Abstract

    Physicochemical Properties of Combustion Ashes of Some Trees (Urban Pruning) Present in the Neotropical Region

  • Open Access

    ARTICLE

    Urban Plant Biomass Residues from the Neotropics and Their Potential for Thermal Energy Generation

    John Freddy Gelves Díaz1,*, Ludovic Dorkis2, Richard Monroy-Sepúlveda1, Sandra Rozo-Rincón1, Gabriel de Jesús Camargo Vargas3

    Journal of Renewable Materials, Vol.11, No.9, pp. 3547-3566, 2023, DOI:10.32604/jrm.2023.029267

    Abstract The material associated with tree pruning in a city in the Colombian neotropics was characterized in order to determine its energy potential. The species studied for their relevance in the territory were Prosopis juliflora, Licania tomentosa, Terminalia catappa, Azadirachta indica, Pithecellobium dulce, Ficus benjamina and Leucaena leucocephala. Moisture content, bulk density, hygroscopic response, elemental chemical analysis, proximal analysis, calorific value, ease of ignition and combustion, thermogravimetric and heat flow analysis, steam generation capacity, and qualitative analysis of gases (mass spectrometry) were determined. The results that were obtained show high initial moisture contents that vary between 37% and 67% and a… More > Graphic Abstract

    Urban Plant Biomass Residues from the Neotropics and Their Potential for Thermal Energy Generation

  • Open Access

    ARTICLE

    Schooling of Students with Cancer and the Role of Teachers: an Exploratory Study in French-Speaking Switzerland

    Scolarité des élèves atteints de cancer et rôle des enseignants : une étude exploratoire en Suisse romande

    M. Diezi, C. Fawer Caputo, F. Naef

    Psycho-Oncologie, Vol.17, No.2, pp. 65-70, 2023, DOI:10.3166/pson-2022-0234

    Abstract Although rare, a diagnosis of a childhood cancer often has a major impact not only on the sick child, his or her family, and friends but also on his or her school environment. Absenteeism secondary to treatment, side effects, and the various cognitive problems that the disease can cause may lead to school dropouts. However, reintegration into a life that is as normal as possible is desirable and contributes to the child’s emotional stability. It requires the collaboration of many people, including teachers, who play an essential role in this path back to normality. Various studies have shown that the… More >

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