Yan Wu¹, Xuerui An¹, Haofan Lv¹, Zhiqiang Zhao¹, Wei Liu^1,2,*, Chunpeng Wan^1,3,*

Phyton-International Journal of Experimental Botany, Vol.94, No.1, pp. 199-207, 2025, DOI:10.32604/phyton.2025.059581 - 24 January 2025

Abstract A novel pair of oleanane nor-triterpenes, with compound 1 featuring a unique 18α-H structure, was isolated from mastic, and this compound represents a noteworthy new entity not previously reported in the literature. The absolute configurations of their structures were further determined using a combination of different analytical methods such as NMR, high-resolution mass spectrometry (HR-MS), ultraviolet (UV), infrared (IR) and single-crystal X-ray diffraction (SXRD). The compound actively mitigated inflammations by efficiently quenching nitric oxide (NO) synthesis within an ex vivo system using lipopolysaccharide activated murine macrophage RAW264.7 cells. Moreover, compound 1 exhibit a better IC₅₀ concentration of More >

Simon Martinez¹, Jürgen Lenz¹, Hans Schindler^1,2, Willi Wendler¹, Stefan Rues³, Karl Schweizerhof^1,*, Sophia Terebesi², Nikolaos Nikitas Giannakopoulos², Marc Schmitter²

CMES-Computer Modeling in Engineering & Sciences, Vol.129, No.3, pp. 1259-1281, 2021, DOI:10.32604/cmes.2021.017422 - 25 November 2021

Abstract The occlusal design plays a decisive role in the fabrication of dental restorations. Dentists and dental technicians depend on mechanical simulations of mandibular movement that are as accurate as possible, in particular, to produce interference-free yet chewing-efficient dental restorations. For this, kinetic data must be available, i.e., movements and deformations under the influence of forces and stresses. In the present study, so-called functional data were collected from healthy volunteers to provide consistent information for proper kinetics. For the latter purpose, biting and chewing forces, electrical muscle activity and jaw movements were registered synchronously, and individual More >

N.Kringos¹, A.Scarpas¹, A.P.S. Selvadurai²

CMES-Computer Modeling in Engineering & Sciences, Vol.28, No.3, pp. 147-160, 2008, DOI:10.3970/cmes.2008.028.147

Abstract This paper presents a numerical approach for the modeling of water flow induced mastic erosion from a permeable asphalt mix and is part of an ongoing effort to model moisture-induced damage in asphalt mixes. Due to the complex composite structure of asphalt mixtures, moisture can infiltrate in various ways into the components and have an adverse effect on its mechanical performance. Depending on the gradation of the asphalt aggregates and the mixing procedure, asphalt structures with a variable permeability may result. Open-graded asphalt mixes are designed with a high interconnected air void content to serve More >