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  • Open Access

    PROCEEDINGS

    High-Temperature Fracture Behavior and Toughening Mechanisms of PIP-C/SiC Composites: An Integrated Experimental and Phase-Field Study

    Kunjie Wang, Chenghai Xu*, Xinliang Zhao, Songhe Meng

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.34, No.1, pp. 1-1, 2025, DOI:10.32604/icces.2025.011534

    Abstract Considering the high-temperature application environment and quasi-brittle characteristics, the high-temperature fracture toughness of C/SiC composites is of great significance for the safety application of components in service.
    In this work, the fracture toughness of PIP-C/SiC composites at 25–1600 ℃ in inert atmosphere was tested. The test results show that the fracture toughness and modes of C/SiC composites have significant temperature dependence and difference in in-plane and out-of-plane orientations. With the rising of temperature, the carrying capacity and KIC of C/SiC composites increase first and then decrease, and an inflection point occurs near the fabrication temperature.… More >

  • Open Access

    ARTICLE

    Numerical Simulation of Microscopic Seepage Mechanisms in Gas Reservoir Storage Systems

    Yulong Zhao1, Yang Luo1,*, Yuming Luo2, Yulai Pang2, Ruihan Zhang1, Zihan Zhao3

    FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.12, pp. 3073-3090, 2025, DOI:10.32604/fdmp.2025.070685 - 31 December 2025

    Abstract The development of underground gas storage (UGS) systems is vital for maintaining stability between energy supply and demand. This study explores the dynamic response mechanisms of carbonate reservoirs subjected to intense injection–production cycling during UGS operations. By integrating three-dimensional digital core technology with a coupled poro-mechanical model, we simulate the pore-scale behavior of a representative Huangcaoxia UGS carbonate core. The results demonstrate that fluid–solid coupling effects markedly amplify permeability reduction, far exceeding the influence of porosity variations alone. More significantly, gas production leads to a pronounced decline in permeability driven by rising effective stress, arising More >

  • Open Access

    ARTICLE

    Numerical Exploration on Load Transfer Characteristics and Optimization of Multi-Layer Composite Pavement Structures Based on Improved Transfer Matrix Method

    Guo-Zhi Li1, Hua-Ping Wang1,2,*, Si-Kai Wang1, Jing-Cheng Zhou1, Ping Xiang3,4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 3165-3195, 2025, DOI:10.32604/cmes.2025.072750 - 23 December 2025

    Abstract Transportation structures such as composite pavements and railway foundations typically consist of multi-layered media designed to withstand high bearing capacity. A theoretical understanding of load transfer mechanisms in these multi-layer composites is essential, as it offers intuitive insights into parametric influences and facilitates enhanced structural performance. This paper employs an improved transfer matrix method to address the limitations of existing theoretical approaches for analyzing multi-layer composite structures. By establishing a two-dimensional composite pavement model, it investigates load transfer characteristics and validates the accuracy through finite element simulation. The proposed method offers a straightforward analytical approach… More >

  • Open Access

    REVIEW

    Mechanistic Insights into the Role of Melatonin in Cancer Cell Chemoresistance

    Russel J. Reiter1,*, Ramaswamy Sharma2,*, Walter Manucha3, Walter Balduini4, Doris Loh5, Demetrios A. Spandidos6, Alejandro Romero7, Vasiliki E. Georgakopoulou8, Wei Zhu9

    BIOCELL, Vol.49, No.11, pp. 2033-2067, 2025, DOI:10.32604/biocell.2025.067661 - 24 November 2025

    Abstract The development of cancer cell resistance to conventional treatments continues to be a major obstacle in the successful treatment of tumors of many types. The discovery of a highly efficient direct and indirect free radical scavenger, melatonin, in the mitochondrial matrix may be a factor in determining both the occurrence of cancer cell drug insensitivity as well as radioresistance. This relates to two of the known hallmarks of cancer, i.e., exaggerated free radical generation in the mitochondria and the development of Warburg type metabolism (glycolysis). The hypothesis elaborated in this report assumes that the high… More >

  • Open Access

    PROCEEDINGS

    Maximizing Sound Absorption in 3D Printed Lattice Structures

    Xinwei Li*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.4, pp. 1-2, 2025, DOI:10.32604/icces.2025.010448

    Abstract Advances in 3D printing have unlocked new opportunities for developing lattice structures tailored for enhanced sound absorption. This work explores methods to maximize sound absorption in microlattice designs by introducing heterogeneity, leveraging dual dissipation mechanisms, and reshaping cavity wall geometries. We present a multilayered Helmholtz resonance (MLHR) analytical model to predict and guide the design of broadband sound-absorbing lattices [1]. Through structural optimization, we demonstrate that heterogeneous microlattices with varying pore and cavity morphologies achieve broadband absorption [2–4], with experimentally validated absorption coefficients exceeding 0.75 across a wide frequency range from 1000 to 6300 Hz.
    Beyond… More >

  • Open Access

    ARTICLE

    Magneto-Electro-Elastic 3D Coupling in Free Vibrations of Layered Plates

    Salvatore Brischetto*, Domenico Cesare, Tommaso Mondino

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 4491-4518, 2025, DOI:10.32604/cmc.2025.068518 - 23 October 2025

    Abstract A three-dimensional (3D) analytical formulation is proposed to put together magnetic, electric and elastic fields to analyze the vibration modes of simply-supported layered piezo-electro-magnetic plates. The present 3D model allows analyses for layered smart plates in both open-circuit and closed-circuit configurations. The second-order differential equations written in the mixed curvilinear reference system govern the magneto-electro-elastic free vibration problem for multilayered plates. This set consists of the 3D equations of motion and the 3D divergence equations for the magnetic induction and electric displacement. Navier harmonic forms in the planar directions and the exponential matrix method in… More >

  • Open Access

    PROCEEDINGS

    Influence of Resin Matrix Rigidity on the Ballistic Performance of PBO and Aramid Fiber Reinforced Composites

    Jia Liu, Yuwu Zhang*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.2, pp. 1-1, 2025, DOI:10.32604/icces.2025.011553

    Abstract The rigidity of the resin matrix is a critical factor affecting the impact resistance of composites [1]. However, the intrinsic relationship between resin matrix rigidity and ballistic performance remains insufficiently understood. To reveal the influence mechanisms of resin matrix rigidity on ballistic performance, this study compares the ballistic limits of PBO-140, PBO-200, Aramid III, and Aramid II fiber reinforced composites with resin matrices of different rigidities (epoxy resin, PX90, and PX30) through ballistic impact tests. The experimental results show that, the ballistic limit of composites with PX90 resin is higher than that of composites with… More >

  • Open Access

    ARTICLE

    An Intelligent Zero Trust Architecture Model for Mitigating Authentication Threats and Vulnerabilities in Cloud-Based Services

    Victor Otieno Mony*, Anselemo Peters Ikoha, Roselida O. Maroko

    Journal of Cyber Security, Vol.7, pp. 395-415, 2025, DOI:10.32604/jcs.2025.070952 - 30 September 2025

    Abstract The widespread adoption of Cloud-Based Services has significantly increased the surface area for cyber threats, particularly targeting authentication mechanisms, which remain among the most vulnerable components of cloud security. This study aimed to address these challenges by developing and evaluating an Intelligent Zero Trust Architecture model tailored to mitigate authentication-related threats in Cloud-Based Services environments. Data was sourced from public repositories, including Kaggle and the National Institute for Standards and Technology MITRE Corporation’s Adversarial Tactics, Techniques, & Common Knowledge (ATT&CK) framework. The study utilized two trust signals: Behavioral targeting system users and Contextual targeting system… More >

  • Open Access

    ARTICLE

    Genome-Wide Gene Expression Profiling in Human Adipose-Derived Mesenchymal Stem Cells

    Sae Hee Cheon1, Sung-Whan Kim2,3,*

    BIOCELL, Vol.49, No.9, pp. 1697-1710, 2025, DOI:10.32604/biocell.2025.068743 - 25 September 2025

    Abstract Objectives: Despite the considerable regenerative capacity exhibited by adipose-derived mesenchymal stem cells (ASCs), their genetic and molecular mechanisms remain incompletely understood. Methods: In this study, we analyzed the global gene expression profile of adipose-derived mesenchymal stem cells (ASCs) using microarray analysis and compared it with stromal vascular fraction (SVF) cells. Results: Microarray analysis revealed that ASCs express elevated levels of genes related to the extracellular matrix (ECM; extracellular matrix) and collagen, which are critical components of tissue remodeling and wound healing. Additionally, genes associated with cell growth, differentiation, motility, and plasticity were highly expressed. When compared… More >

  • Open Access

    ARTICLE

    3D Exact Magneto-Electro-Elastic Static Analysis of Multilayered Plates

    Salvatore Brischetto*, Domenico Cesare, Tommaso Mondino

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.1, pp. 643-668, 2025, DOI:10.32604/cmes.2025.066313 - 31 July 2025

    Abstract This study proposes a three-dimensional (3D) coupled magneto-electro-elastic problem for the static analysis of multilayered plates embedding piezomagnetic and piezoelectric layers by considering both sensor and actuator configurations. The 3D governing equations for the magneto-electro-elastic static behavior of plates are explicitly show that are made by the three 3D equilibrium equations, the 3D divergence equation for magnetic induction, and the 3D divergence equation for the electric displacement. The proposed solution involves the exponential matrix in the thickness direction and primary variables’ harmonic forms in the in-plane ones. A closed-form solution is performed considering simply-supported boundary… More >

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