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  • Open Access

    ARTICLE

    miR-200b-3p accelerates progression of pituitary adenomas by negatively regulating expression of RECK

    XIAOXI WANG1, YANFEI JIA2, QIANG LI2, QIANG YANG2, YINGFENG LIU1, BEIFENG WEI1, XIANG NIU1, YINJIE ZHANG1, XIAODONG LUO2, ZIYU ZHAO1,*, PENG WANG1,*

    Oncology Research, Vol.32, No.5, pp. 933-941, 2024, DOI:10.32604/or.2023.042581

    Abstract MicroRNA (miR)-200b-3p has been associated with many tumors, but its involvement in pituitary adenoma is unclear. This study investigated the molecular mechanism underlying miR-200b-3p regulation in pituitary adenomas to provide a theoretical basis for treatment. Bioinformatics was used to analyze pituitary adenoma-related genes and screen new targets related to RECK and miRNA. As well, the relationship between miR-200b-3p and RECK protein was verified using a double-luciferase reporter gene assay. The expression of miR-200b-3p in clinical samples was analyzed by in situ hybridization. Transfection of the miR-200b-3p inhibitor and small interfering-RECK (si-RECK) was verified by qPCR. GH3 cell viability and proliferation… More >

  • Open Access

    ARTICLE

    Matrix Assisted Laser Desorption Ionization Time of Flight (MALDI-TOF)-Mass Spectrometry and 13C-NMR-Identified New Compounds in Paraberlinia bifoliolata (Ekop-Beli) Bark Tannins

    Liliane Nga1, Benoit Ndiwe1,2, Achille Bernard Biwolé1, Antonio Pizzi3,*, Jean Jalin Eyinga Biwole1, Joseph Zobo Mfomo1

    Journal of Renewable Materials, Vol.12, No.3, pp. 553-568, 2024, DOI:10.32604/jrm.2023.046568

    Abstract Extracts of plant origin, particularly tannins, are attracting growing interest for the sustainable development of materials in the industrial sector. The discovery of new tannins is therefore necessary. The aim of this work was to contribute to the understanding of the properties of Paraberlinia bifoliolata tannin by Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectroscopy MALDI-TOF/MS and Carbon 13 Nuclear Magnetic Resonance (13C NMR). The chemical composition of tannin extracted from Paraberlinia bifoliolata bark was determined, as was the mechanical strength of the resin hardened with Acacia nilotica extracts. Yield by successive water extraction was 35%. MALDI-TOF/MS analysis… More >

  • Open Access

    REVIEW

    Overview of Jute Fibre as Thermoplastic Matrix Polymer Reinforcement

    Tezara Cionita1,*, Mohammad Hazim Mohamad Hamdan2, Januar Parlaungan Siregar3,4,*, Deni Fajar Fitriyana5, Ramli Junid6, Wong Ling Shing7, Jamiluddin Jaafar8, Agustinus Purna Irawan9, Teuku Rihayat10, Rifky Ismail11, Athanasius Priharyoto Bayuseno11, Emilianus Jehadus12

    Journal of Renewable Materials, Vol.12, No.3, pp. 457-483, 2024, DOI:10.32604/jrm.2024.045814

    Abstract Recent decades have seen a substantial increase in interest in research on natural fibres that is aligned with sustainable development goals (SDGs). Due to their renewable resources and biodegradability, natural fiber-reinforced composites have been investigated as a sustainable alternative to synthetic materials to reduce the usage of hazardous waste and environmental pollution. Among the natural fibre, jute fibre obtained from a bast plant has an increasing trend in the application, especially as a reinforcement material. Numerous research works have been performed on jute fibre with regard to reinforced thermoset and thermoplastic composites. Nevertheless, current demands on sustainable materials have required… More >

  • Open Access

    ARTICLE

    NFT Security Matrix: Towards Modeling NFT Ecosystem Threat

    Peng Liao1, Chaoge Liu2, Jie Yin1,3,*, Zhi Wang2, Xiang Cui2

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3255-3285, 2024, DOI:10.32604/cmes.2024.043855

    Abstract Digital assets have boomed over the past few years with the emergence of Non-fungible Tokens (NFTs). To be specific, the total trading volume of digital assets reached an astounding $55.5 billion in 2022. Nevertheless, numerous security concerns have been raised by the rapid expansion of the NFT ecosystem. NFT holders are exposed to a plethora of scams and traps, putting their digital assets at risk of being lost. However, academic research on NFT security is scarce, and the security issues have aroused rare attention. In this study, the NFT ecological process is comprehensively explored. This process falls into five different… More >

  • Open Access

    ARTICLE

    Placenta-derived mesenchymal stem cells attenuate secondary brain injury after controlled cortical impact in rats by inhibiting matrix metalloproteinases

    PING YANG1,2,3, YUANXIANG LAN1,2, ZHONG ZENG1,2, YAN WANG1,2, HECHUN XIA1,2,*

    BIOCELL, Vol.48, No.1, pp. 149-162, 2024, DOI:10.32604/biocell.2023.042367

    Abstract Background: As a form of biological therapy, placenta-derived mesenchymal stem cells (PDMSCs) exhibit considerable promise in addressing the complex pathological processes of traumaticbrain injury (TBI) due to their multi-target and multi-pathway mode of action. Material & Methods: This study investigates the protective mechanisms and benefits of PDMSCs in mitigating the effects of controlled cortical impact (CCI) in rats and glutamate-induced oxidative stress injury in HT22 cells in vitro. Our primary objective is to provide evidence supporting the clinical application of PDMSCs. Results: In the in vivo arm of our investigation, we observed a swift elevation of matrix metalloproteinase-9 (MMP-9) in… More > Graphic Abstract

    Placenta-derived mesenchymal stem cells attenuate secondary brain injury after controlled cortical impact in rats by inhibiting matrix metalloproteinases

  • Open Access

    ARTICLE

    Multi-Branch Fault Line Location Method Based on Time Difference Matrix Fitting

    Hua Leng1, Silin He2, Jian Qiu3, Feng Liu4,*, Xinfei Huang4, Jiran Zhu2

    Energy Engineering, Vol.121, No.1, pp. 77-94, 2024, DOI:10.32604/ee.2023.028340

    Abstract The distribution network exhibits complex structural characteristics, which makes fault localization a challenging task. Especially when a branch of the multi-branch distribution network fails, the traditional multi-branch fault location algorithm makes it difficult to meet the demands of high-precision fault localization in the multi-branch distribution network system. In this paper, the multi-branch mainline is decomposed into single branch lines, transforming the complex multi-branch fault location problem into a double-ended fault location problem. Based on the different transmission characteristics of the fault-traveling wave in fault lines and non-fault lines, the endpoint reference time difference matrix S and the fault time difference… More >

  • Open Access

    ARTICLE

    On Factorization of N-Qubit Pure States and Complete Entanglement Analysis of 3-Qubit Pure States Containing Exactly Two Terms and Three Terms

    Dhananjay P. Mehendale1,*, Madhav R. Modak2

    Journal of Quantum Computing, Vol.5, pp. 15-24, 2023, DOI:10.32604/jqc.2023.043370

    Abstract A multi-qubit pure quantum state is called separable when it can be factored as the tensor product of 1-qubit pure quantum states. Factorizing a general multi-qubit pure quantum state into the tensor product of its factors (pure states containing a smaller number of qubits) can be a challenging task, especially for highly entangled states. A new criterion based on the proportionality of the rows of certain associated matrices for the existence of certain factorization and a factorization algorithm that follows from this criterion for systematically extracting all the factors is developed in this paper. 3-qubit pure states play a crucial… More >

  • Open Access

    ARTICLE

    Multidomain Correlation-Based Multidimensional CSI Tensor Generation for Device-Free Wi-Fi Sensing

    Liufeng Du1,*, Shaoru Shang1, Linghua Zhang2, Chong Li1, Jianing Yang3, Xiyan Tian1

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.2, pp. 1749-1767, 2024, DOI:10.32604/cmes.2023.030144

    Abstract Due to the fine-grained communication scenarios characterization and stability, Wi-Fi channel state information (CSI) has been increasingly applied to indoor sensing tasks recently. Although spatial variations are explicitly reflected in CSI measurements, the representation differences caused by small contextual changes are easily submerged in the fluctuations of multipath effects, especially in device-free Wi-Fi sensing. Most existing data solutions cannot fully exploit the temporal, spatial, and frequency information carried by CSI, which results in insufficient sensing resolution for indoor scenario changes. As a result, the well-liked machine learning (ML)-based CSI sensing models still struggling with stable performance. This paper formulates a… More >

  • Open Access

    ARTICLE

    Construction of a Computational Scheme for the Fuzzy HIV/AIDS Epidemic Model with a Nonlinear Saturated Incidence Rate

    Muhammad Shoaib Arif1,2,*, Kamaleldin Abodayeh1, Yasir Nawaz2

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.2, pp. 1405-1425, 2024, DOI:10.32604/cmes.2023.028946

    Abstract This work aimed to construct an epidemic model with fuzzy parameters. Since the classical epidemic model does not elaborate on the successful interaction of susceptible and infective people, the constructed fuzzy epidemic model discusses the more detailed versions of the interactions between infective and susceptible people. The next-generation matrix approach is employed to find the reproduction number of a deterministic model. The sensitivity analysis and local stability analysis of the system are also provided. For solving the fuzzy epidemic model, a numerical scheme is constructed which consists of three time levels. The numerical scheme has an advantage over the existing… More >

  • Open Access

    ARTICLE

    Coordinate-Parametric Matrix Model Inspired Square-Conjoint Pattern in Cross Woven for Conventional Bamboo Mat

    Ye Fu1, Liwen Deng1,*, Jinbo Hu2,3,*, Ti Li3, Shanshan Chang2

    Journal of Renewable Materials, Vol.11, No.12, pp. 4025-4038, 2023, DOI:10.32604/jrm.2023.028454

    Abstract In the study, it is proposed that a coordinate-parametric matrix model is performed to a square-conjoint pattern of cross woven (SCPCW) in the bamboo mat. The patterns of SCPCW are firstly detected according to the perspective of configuration, which is divided into the basic-monomer shape and the basic combination shape. Secondly, the compositions of design patterns in SCPCW are analyzed to attain the trend of curve shape. Based on the coordinate-parametric matrix model, the specimens of SCPCW are subsequently accomplished to elaborate the woven logic of bamboo mats. The digital innovation of SCPCW, defined by a mathematical resolution, is implemented… More > Graphic Abstract

    Coordinate-Parametric Matrix Model Inspired Square-Conjoint Pattern in Cross Woven for Conventional Bamboo Mat

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