Yimin Liu^1,#, Bin Liu^2,3,4,#, Huabin Gao¹, Jinlong Wang⁵, Jingya Duan¹, Xiaolan Huang¹, Yuexi Liu¹, Ying Huang¹, Wenjing Liao¹, Ruonan Li^1,*, Hua Linghu^1,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.069007 - 30 December 2025

Abstract Objectives: High-grade serous ovarian cancer (HGSOC), the most common subtype of epithelial ovarian cancer (EOC), exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis. Human epididymis protein 4 (HE4), a key diagnostic biomarker for ovarian cancer, is involved in fibrotic processes in several non-malignant diseases. Given the clinical significance of stromal fibrosis in HGSOC and the potential link between HE4 and fibrosis, this study aimed to investigate the role of HE4 in the formation of stromal fibrosis in HGSOC. Methods: A total of 126 patients with gynecological conditions were included and divided into… More > Graphic Abstract

Junwen Huo, Haicheng Liang, Weiye Dong, Xiaoming Du^*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-20, 2026, DOI:10.32604/cmc.2025.073285 - 09 December 2025

Abstract With the rapid advancement of electromagnetic launch technology, enhancing the structural stability and thermal resistance of armatures has become essential for improving the overall efficiency and reliability of railgun systems. Traditional aluminum alloy armatures often suffer from severe ablation, deformation, and uneven current distribution under high pulsed currents, which limit their performance and service life. To address these challenges, this study employs the Johnson–Cook constitutive model and the finite element method to develop armature models of aluminum matrix composites with varying heterogeneous graphene volume fractions. The temperature, stress, and strain of the armatures during operation… More >

Salahudin Robo^1,2, Triyanna Widiyaningtyas^1,*, Wahyu Sakti Gunawan Irianto¹

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-19, 2026, DOI:10.32604/cmc.2025.073011 - 09 December 2025

Abstract Recommendation systems are an integral and indispensable part of every digital platform, as they can suggest content or items to users based on their respective needs. Collaborative filtering is a technique often used in various studies, which produces recommendations by analyzing similarities between users and items based on their behavior. Although often used, traditional collaborative filtering techniques still face the main challenge of sparsity. Sparsity problems occur when the data in the system is sparse, meaning that only a portion of users provide feedback on some items, resulting in inaccurate recommendations generated by the system.… More >

Yi Cao¹, Kuo Zhang¹, Chengsheng Yuan^2,*, Linglong Zhu¹, Wentao Ge²

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-24, 2026, DOI:10.32604/cmc.2025.070158 - 09 December 2025

Abstract Generative steganography uses generative stego images to transmit secret message. It also effectively defends against statistical steganalysis. However, most existing methods focus primarily on matching the feature distribution of training data, often neglecting the sequential continuity between moves in the game. This oversight can result in unnatural patterns that deviate from real user behavior, thereby reducing the security of the hidden communication. To address this issue, we design a Gomoku agent based on the AlphaZero algorithm. The model engages in self-play to generate a sequence of plausible moves. These moves form the basis of the… More >

Hongyu Zhao^1,2, Shengsheng Wang^1,2,*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-25, 2026, DOI:10.32604/cmc.2025.068426 - 10 November 2025

Abstract Driven by advancements in mobile internet technology, images have become a crucial data medium. Ensuring the security of image information during transmission has thus emerged as an urgent challenge. This study proposes a novel image encryption algorithm specifically designed for grayscale image security. This research introduces a new Cantor diagonal matrix permutation method. The proposed permutation method uses row and column index sequences to control the Cantor diagonal matrix, where the row and column index sequences are generated by a spatiotemporal chaotic system named coupled map lattice (CML). The high initial value sensitivity of the… More >

Guo-Zhi Li¹, Hua-Ping Wang^1,2,*, Si-Kai Wang¹, Jing-Cheng Zhou¹, Ping Xiang^3,4,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 3165-3195, 2025, DOI:10.32604/cmes.2025.072750 - 23 December 2025

Abstract Transportation structures such as composite pavements and railway foundations typically consist of multi-layered media designed to withstand high bearing capacity. A theoretical understanding of load transfer mechanisms in these multi-layer composites is essential, as it offers intuitive insights into parametric influences and facilitates enhanced structural performance. This paper employs an improved transfer matrix method to address the limitations of existing theoretical approaches for analyzing multi-layer composite structures. By establishing a two-dimensional composite pavement model, it investigates load transfer characteristics and validates the accuracy through finite element simulation. The proposed method offers a straightforward analytical approach… More >

Russel J. Reiter^1,*, Ramaswamy Sharma^2,*, Walter Manucha³, Walter Balduini⁴, Doris Loh⁵, Demetrios A. Spandidos⁶, Alejandro Romero⁷, Vasiliki E. Georgakopoulou⁸, Wei Zhu⁹

BIOCELL, Vol.49, No.11, pp. 2033-2067, 2025, DOI:10.32604/biocell.2025.067661 - 24 November 2025

Abstract The development of cancer cell resistance to conventional treatments continues to be a major obstacle in the successful treatment of tumors of many types. The discovery of a highly efficient direct and indirect free radical scavenger, melatonin, in the mitochondrial matrix may be a factor in determining both the occurrence of cancer cell drug insensitivity as well as radioresistance. This relates to two of the known hallmarks of cancer, i.e., exaggerated free radical generation in the mitochondria and the development of Warburg type metabolism (glycolysis). The hypothesis elaborated in this report assumes that the high… More >

Xinwei Li^*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.4, pp. 1-2, 2025, DOI:10.32604/icces.2025.010448

Abstract Advances in 3D printing have unlocked new opportunities for developing lattice structures tailored for enhanced sound absorption. This work explores methods to maximize sound absorption in microlattice designs by introducing heterogeneity, leveraging dual dissipation mechanisms, and reshaping cavity wall geometries. We present a multilayered Helmholtz resonance (MLHR) analytical model to predict and guide the design of broadband sound-absorbing lattices [1]. Through structural optimization, we demonstrate that heterogeneous microlattices with varying pore and cavity morphologies achieve broadband absorption [2–4], with experimentally validated absorption coefficients exceeding 0.75 across a wide frequency range from 1000 to 6300 Hz.
Beyond… More >

Salvatore Brischetto^*, Domenico Cesare, Tommaso Mondino

CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 4491-4518, 2025, DOI:10.32604/cmc.2025.068518 - 23 October 2025

Abstract A three-dimensional (3D) analytical formulation is proposed to put together magnetic, electric and elastic fields to analyze the vibration modes of simply-supported layered piezo-electro-magnetic plates. The present 3D model allows analyses for layered smart plates in both open-circuit and closed-circuit configurations. The second-order differential equations written in the mixed curvilinear reference system govern the magneto-electro-elastic free vibration problem for multilayered plates. This set consists of the 3D equations of motion and the 3D divergence equations for the magnetic induction and electric displacement. Navier harmonic forms in the planar directions and the exponential matrix method in… More >

Jia Liu, Yuwu Zhang^*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.2, pp. 1-1, 2025, DOI:10.32604/icces.2025.011553

Abstract The rigidity of the resin matrix is a critical factor affecting the impact resistance of composites [1]. However, the intrinsic relationship between resin matrix rigidity and ballistic performance remains insufficiently understood. To reveal the influence mechanisms of resin matrix rigidity on ballistic performance, this study compares the ballistic limits of PBO-140, PBO-200, Aramid III, and Aramid II fiber reinforced composites with resin matrices of different rigidities (epoxy resin, PX90, and PX30) through ballistic impact tests. The experimental results show that, the ballistic limit of composites with PX90 resin is higher than that of composites with… More >