Francisco Javier Ruperti-Repilado^1,#,*, Magalie Ladouceur^2,#, Pastora Gallego³, Laura Dos⁴, Joaquin Rueda Soriano⁵, Berto Bouma⁶, Harald Gabriel⁷, Markus Schwerzmann¹, Judith Bouchardy^8,9, Daniel Tobler^10,#, Matthias Greutmann^11,#

Congenital Heart Disease, Vol.15, No.5, pp. 309-338, 2020, DOI:10.32604/CHD.2020.012599

Abstract Background: Long-term outcomes in adults with prior arterial switch operation (ASO) have not yet been well defined. The aim of this study is to elucidate incidence and predictors of adverse cardiac outcomes in a prospectively followed cohort of adults after their ASO. Methods: The comprehensive longterm follow up of adults with ASO is a project within the European collaboration for prospective outcome research in congenital heart disease (EPOCH). It is designed as a prospective, international multicenter cohort study. Consecutive patients (age ≥ 16 years) with prior ASO will be included at 11 European tertiary care centers. Participants will be followed… More >

MARÍA ELISA MILLÁN¹, MARÍA FERNANDA MARRA¹, LEONARDO ANDRÉS SALVARREDI^1,2,3, EMILIO FERNANDO LIZARRAGA^4,*, LUIS ALBERTO LOPEZ^1,*

BIOCELL, Vol.44, No.3, pp. 293-299, 2020, DOI:10.32604/biocell.2020.012342

Abstract The ajenjo, Artemisia mendozana DC. var. mendozana (Asteraceae), grows in the Andean foothills of Mendoza and San Juan, Argentina, and is used as a medicinal plant for its antispasmodic and antifungal properties. The aim of this work was to obtain fractions of a chloroform extract of ajenjo leaves and to evaluate the in vitro effects on proliferation, viability and clonogenicity of B16-F0 melanoma cells. Using a silica gel chromatography column, 120 fractions were collected and grouped according to the chromatographic profile in 9 main fractions (F1–F9). Their major compounds identified were: terpenes (F1), terpenes and sesquiterpene lactones (F2–F3), sesquiterpenes (F4–F6)… More >

Yinghua Zhang^1,2, Jian Liu¹, Yunfeng Peng¹, Yanfang Dong², Changming Zhao^3,*

CMES-Computer Modeling in Engineering & Sciences, Vol.125, No.1, pp. 239-257, 2020, DOI:10.32604/cmes.2020.010778

Abstract Aiming for ultra-reliable low-latency wireless communications required in industrial internet of things (IIoT) applications, this paper studies a simple cognitive radio non-orthogonal multiple access (CR-NOMA) downlink system. This system consists of two secondary users (SUs) dynamically interfered by the primary user (PU), and its performance is characterized by the outage probability of the SU communications. This outage probability is calculated under two conditions where, a) the transmission of PU starts after the channel state information (CSI) is acquired, so the base station (BS) is oblivious of the interference, and b) when the BS is aware of the PU interference, and… More >

Naveed Rabbani^1,*, Sarah Hofman DeYoung², Ronald L. Gibson², Jeffrey Conwell¹, Jason F. Deen¹

Congenital Heart Disease, Vol.15, No.4, pp. 197-201, 2020, DOI:10.32604/CHD.2020.011527

Abstract Persistent left superior vena cava (PLSVC) is a relatively common congenital venous anomaly that typically drains into the coronary sinus without hemodynamic significance. Rarely a PLSVC drains directly into the left atrium, forming a right-to-left shunt that can result in hypoxemia and potential paradoxical embolism. We present the case of a 2-year-old medically complex child on chronic mechanical ventilation with eventual diagnosis of episodic hypoxemia due to a PLSVC draining into the left atrium with position-dependent venous flow. The lesion was identified with contrast echocardiography and cardiac MRI. Subsequent occlusion with a vascular plug resulted in resolution of the child’s… More >

Alejandro R. Peirone^1,*, Alejandro E. Contreras², Carolina Carrizo², Mailén Konicoff², Raúl O. Cayre³

Congenital Heart Disease, Vol.15, No.4, pp. 267-274, 2020, DOI:10.32604/CHD.2020.013199

Abstract A 43-year-old woman with a past medical history of aortic coarctation surgically repaired at the age of 3 years using an end-to-end anastomosis, presented with 2 years complain of increasing dyspnea and fatigue with exercise associated to frequent palpitations. During extensive work-up, she was found to have a partial anomalous pulmonary venous connection (PAPVC) with “dual drainage” represented by a communication between the right pulmonary veins draining into the left atrium and the innominate vein via an anomalous vein due to a persistence of early connections between the sinus of the right pulmonary veins and the cardinal veins system in… More >

Haoliang Zhang^1,*, Xiaowei Xing², Yang Liu¹, Shuangli Li¹, Weiyuan Li³

Oncologie, Vol.22, No.2, pp. 107-116, 2020, DOI:10.32604/oncologie.2020.012494

Abstract Lung cancer is the leading cause of death in cancer patients. Based on a modular and comprehensive analysis method, it is intended to identify their common pathogenesis. We downloaded data and analyzed differences in lung adenocarcinoma samples, lung squamous cell carcinoma samples, and normal samples. Co-expression analysis, enrichment analysis, and hypergeometric testing were used to predict transcription factors, ncRNAs, and retrospective target genes. We get 4596 differentially expressed genes in common differences in high multiples and clustered into 14 modules dysfunction. The 14 genes (including DOK2, COL5A1, and TSPAN8) have the highest connectivity in the dysfunction module and are identified… More >

Jianzhong Li¹, DexiangMei¹, Dong Deng¹, Imran Khan², Peerapong Uthansakul^{3, *}

CMC-Computers, Materials & Continua, Vol.65, No.2, pp. 1571-1590, 2020, DOI:10.32604/cmc.2020.011822

Abstract Non-orthogonal multiple access (NOMA) is one of the key 5G technology which can improve spectrum efficiency and increase the number of user connections by utilizing the resources in a non-orthogonal manner. NOMA allows multiple terminals to share the same resource unit at the same time. The receiver usually needs to configure successive interference cancellation (SIC). The receiver eliminates co-channel interference (CCI) between users and it can significantly improve the system throughput. In order to meet the demands of users and improve fairness among them, this paper proposes a new power allocation scheme. The objective is to maximize user fairness by… More >

Jianfeng Guan^*, Jiawei Li, Zhongbai Jiang

Intelligent Automation & Soft Computing, Vol.25, No.1, pp. 131-141, 2019, DOI:10.31209/2018.100000050

Abstract The traditional web anomaly detection systems face the challenges derived from the constantly evolving of the web malicious attacks, which therefore result in high false positive rate, poor adaptability, easy over-fitting, and high time complexity. Due to these limitations, we need a new anomaly detection system to satisfy the requirements of enterprise-level anomaly detection. There are lots of anomaly detection systems designed for different application domains. However, as for web anomaly detection, it has to describe the network accessing behaviours characters from as many dimensions as possible to improve the performance. In this paper we design and implement a Multidimensional… More >

Hao Dang^*

Oncologie, Vol.22, No.1, pp. 35-42, 2020, DOI:10.32604/oncologie.2020.012485

Abstract This study aimed to explore the expression and diagnostic performance of miR-586 and miR-493 in patients with osteosarcoma. We enrolled 63 patients with osteosarcoma treated between May 2016 and May 2019 as the experimental group and 55 healthy volunteers who underwent physical examination during the same period as the control group. We detected miR-586 and miR-493 expression in serum, normal bone tissue, and tumor samples. We also evaluated the relationship between clinical indicators and the miR-586 and miR-493 expression levels. The correlation between the serum and osteosarcoma tissue expression of miR-586 and miR-493 was examined by Pearson analysis. Furthermore, the… More >

Jingjing He^1,2, Lingyi Zhang², Dan Guo³, Xingwen Han⁴, Hui Zhang⁵, Liang Wang², Youcheng Zhang^1,*

Oncologie, Vol.22, No.1, pp. 1-12, 2020, DOI:10.32604/oncologie.2020.012436

Abstract Hepatocellular carcinoma (HCC) ranks the sixth place of most common cancers. Meanwhile, it is the tertiary mortality cause of cancer. There is no effective therapeutic method to prevent and treat the liver cancer. Sinomenine is a kind of Chinese traditional medicine herbal, it is reported that it can inhibit the viability of several cancer cells. The study is to explore whether sinomenine is also able to inhibit the cell viability of HCC and its potential mechanism. The IC50 of sinomenine in BEL-7402 cells was 5.351 mmol/L, and the IC50 of sinomenine in SMMC-7721 cells was 6.204 mmol/L. The gene expression… More >